FlyBase Allele Report: Scer\GAL4[C57]

General Information

Symbol

Scer\GAL4^C57

Species

S. cerevisiae

Name

FlyBase ID

FBal0117655

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GawB}C57

Carried in Construct

Also Known As

C57-GAL4, BG57-GAL4, C57, c57 gal4, BG57, Gal4-C57

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Budnik et al., 1996)

Progenitor genotype

Associated Insertion(s)

P{GawB}C57

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GawB}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

somatic muscle cell

(Packard et al., 2002)

larval somatic muscle cell

(Gorczyca et al., 2007)

electron microscopy

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

somatic muscle cell

(Wolfgang et al., 2004)

Additional Information

Statement

Reference

Drives expression in larval body wall muscles.

(FlyBase Curators, 2017)

Marker for

somatic muscle cell

(Wolfgang et al., 2004, Packard et al., 2002)

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal behavior | larval stage, with LamC^R564P.UAS

(Mohar et al., 2025)

abnormal heat stress response, with Hsap\TOR1A^ΔE.UAS

(Lee et al., 2009)

abnormal heat stress response, with Hsap\TOR1A^ΔFY.UAS

(Lee et al., 2009)

abnormal locomotor behavior | adult stage | progressive, with Torsin^RNAi.UAS.WIZ

(Nguyen et al., 2016)

abnormal locomotor behavior | heat sensitive, with Hsap\TOR1A^ΔE.UAS

(Koh et al., 2004)

abnormal locomotor behavior | larval stage, with LamC^G489V.UAS

(Dialynas et al., 2015)

abnormal locomotor behavior | larval stage, with LamC^M553R.UAS

(Dialynas et al., 2015)

abnormal locomotor behavior | larval stage, with LamC^N496I.UAS

(Dialynas et al., 2015)

abnormal locomotor behavior | larval stage, with LamC^V528P.UAS

(Dialynas et al., 2015)

abnormal locomotor behavior | larval stage, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2015)

abnormal locomotor behavior | larval stage, with Sod1^GD7385

(Peng et al., 2019)

abnormal locomotor behavior | larval stage, with Sod2^HMS00499

(Peng et al., 2019)

abnormal locomotor behavior | larval stage, with Tbce^RNAi.UAS.cJa

(Jin et al., 2009)

abnormal locomotor behavior | larval stage, with Tbce^UAS.cJa

(Jin et al., 2009)

abnormal locomotor behavior | third instar larval stage, with cbc^HMC06558

(Schmidt et al., 2022)

abnormal locomotor behavior | third instar larval stage, with LamC^G489V.UAS

(Dialynas et al., 2012)

abnormal locomotor behavior | third instar larval stage, with LamC^M553R.UAS

(Dialynas et al., 2012)

abnormal locomotor behavior | third instar larval stage, with LamC^N496I.UAS

(Dialynas et al., 2012)

abnormal locomotor behavior | third instar larval stage, with LamC^V528P.UAS

(Dialynas et al., 2012)

abnormal locomotor behavior | third instar larval stage, with Rh50^GD3847

(Lecompte et al., 2020)

abnormal neuroanatomy, with Arp2^GD14716

(Nahm et al., 2010)

abnormal neuroanatomy, with Arp3^GD12273

(Nahm et al., 2010)

abnormal neuroanatomy, with BacA\p35^UAS.cHa

(Liu et al., 2010)

abnormal neuroanatomy, with Cdc42^KK108698

(Nahm et al., 2010)

abnormal neuroanatomy, with Cip4^NIG.15015R

(Nahm et al., 2010)

abnormal neuroanatomy, with Diap1^{UAS.Tag:MYC.cBa}

(Liu et al., 2010)

abnormal neuroanatomy, with fz2^{C.UAS.NLS.Tag:MYC}

(Ataman et al., 2006)

abnormal neuroanatomy, with gbb^UAS.GFP

(Nahm et al., 2010)

abnormal neuroanatomy, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Mozer and Sandstrom, 2012)

abnormal neuroanatomy, with Scer\UBP2^UAS.cDa

(Liu et al., 2010)

abnormal neuroanatomy, with WASp^GD1559

(Nahm et al., 2010)

abnormal neuroanatomy | larval stage, with Adcy1^GD3358

(Tsai et al., 2012)

abnormal neuroanatomy | larval stage, with Adcy1^KK109441

(Tsai et al., 2012)

abnormal neuroanatomy | larval stage, with atl^R192Q.UAS

(Lee et al., 2009)

abnormal neuroanatomy | larval stage, with baz^GD1384

(Ramachandran et al., 2009)

abnormal neuroanatomy | larval stage, with baz^RNAi.cRa.UAS

(Ramachandran et al., 2009)

abnormal neuroanatomy | larval stage, with Madm^GD7155, Scer\GAL4^elav-C155

(Mushtaq et al., 2022)

abnormal neuroanatomy | larval stage, with Pten^dj189

(Ramachandran et al., 2009)

abnormal neuroanatomy | larval stage, with Pten^{RNAi.Exel.UAS}

(Ramachandran et al., 2009)

abnormal neuroanatomy | larval stage, with Sac1^GD2238

(Forrest et al., 2013)

abnormal neuroanatomy | larval stage, with Tbce^RNAi.UAS.cJa

(Jin et al., 2009)

abnormal neuroanatomy | larval stage, with Tbce^UAS.cJa

(Jin et al., 2009)

abnormal neuroanatomy | larval stage, with Torsin^RNAi.UAS.WIZ

(Nguyen et al., 2016)

abnormal neuroanatomy | larval stage, with Torsin^UAS.cKa

(Nguyen et al., 2016)

abnormal neuroanatomy | larval stage, with Vap33^GD3990

(Forrest et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Alk::Hsap\NPM1^UAS.act

(Rohrbough et al., 2013)

abnormal neuroanatomy | third instar larval stage, with gbb^UAS.GFP

(Nahm et al., 2010)

abnormal neuroanatomy | third instar larval stage, with Kat60^UAS.cMa

(Mao et al., 2014)

abnormal neuroanatomy | third instar larval stage, with LanA^9-32, LanA^GD6022

(Tsai et al., 2012)

abnormal neuroanatomy | third instar larval stage, with LanA^C01-190

(Tsai et al., 2012)

abnormal neuroanatomy | third instar larval stage, with Mad^GD4121

(Fuentes-Medel et al., 2012)

abnormal neuroanatomy | third instar larval stage, with nanos^{αTub84B.3'UTR.UAS}

(Menon et al., 2009)

abnormal neuroanatomy | third instar larval stage, with Nlg2^UAS.cSa

(Chen et al., 2012)

abnormal neuroanatomy | third instar larval stage, with put^GD49

(Fuentes-Medel et al., 2012)

abnormal neuroanatomy | third instar larval stage, with put^KK102676

(Fuentes-Medel et al., 2012)

abnormal neuroanatomy | third instar larval stage, with Torsin^E177Q.UAS

(Jokhi et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Torsin^KK107949

(Jokhi et al., 2013)

abnormal neuroanatomy | third instar larval stage, with Torsin^ΔE.UAS

(Jokhi et al., 2013)

abnormal neurophysiology, with Csp^GD10571, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC

(Brusich et al., 2015)

abnormal neurophysiology, with GluRIIC^RNAi.UAS.cBa

(Brusich et al., 2015)

abnormal neurophysiology, with GluRIIC^RNAi.UAS.cBa, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC

(Brusich et al., 2015)

abnormal neurophysiology, with Hsap\APP^{Aβ42.UAS.Tag:SS(rPENK)}

(Chiang et al., 2009)

abnormal neurophysiology, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Mozer and Sandstrom, 2012)

abnormal neurophysiology, with Scer\GAL4^elav-C155, Scer\GAL4^sca.PC, cac^KK101478

(Brusich et al., 2015)

abnormal neurophysiology | larval stage, with aPKC^RNAi.cRa.UAS

(Ramachandran et al., 2009)

abnormal neurophysiology | larval stage, with baz^815-8, baz^RNAi.cRa.UAS

(Ramachandran et al., 2009)

abnormal neurophysiology | larval stage, with DCAF12^UAS.cPa

(Patrón et al., 2019)

abnormal neurophysiology | larval stage, with Madm^GD7155, Scer\GAL4^elav-C155

(Mushtaq et al., 2022)

abnormal neurophysiology | larval stage, with Pi3K68D^AH1, Pi3K68D^UAS.EGFP

(Hauswirth et al., 2018)

abnormal neurophysiology | larval stage, with Pi3K68D^HMS01296, Scer\GAL4^sca.PU

(Hauswirth et al., 2018)

abnormal neurophysiology | larval stage, with Pi3K68D^UAS.EGFP

(Hauswirth et al., 2018)

abnormal neurophysiology | larval stage, with Pten^{RNAi.Exel.UAS}, Pten^dj189

(Ramachandran et al., 2009)

abnormal neurophysiology | larval stage, with Rab11^GD11761

(Hauswirth et al., 2018)

abnormal neurophysiology | third instar larval stage, with Csk^UAS.YFP, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC

(Spring et al., 2016)

abnormal neurophysiology | third instar larval stage, with GluRIIC^RNAi.UAS.cBa, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC

(Spring et al., 2016)

abnormal neurophysiology | third instar larval stage, with mir-289^UAS.mCherry

(Kuklin et al., 2017)

abnormal size | larval stage, with DCAF12^UAS.cPa

(Patrón et al., 2019)

abnormal size | larval stage, with LamC^R564P.UAS

(Walker et al., 2023)

abnormal size | third instar larval stage, with koi^{UAS.PA.Tag:V5}

(Tan et al., 2018)

decreased rate of larval locomotory behavior, with LamC^G489V.UAS

(Shaw et al., 2022)

decreased rate of larval locomotory behavior, with LamC^K521Q.UAS

(Shaw et al., 2022)

decreased rate of larval locomotory behavior, with LamC^R237P.UAS

(Shaw et al., 2022)

decreased rate of larval locomotory behavior, with LamC^R564P.UAS

(Mohar et al., 2025, Walker et al., 2023)

decreased rate of larval locomotory behavior, with LamC^ΔK47.UAS

(Shaw et al., 2022)

decreased rate of larval locomotory behavior, with Msp300^HMS00632

(Shaw et al., 2022)

decreased size | larval stage, with Cul4^KK101901

(Patrón et al., 2019)

decreased size | larval stage, with LamC^R564P.UAS

(Mohar et al., 2025)

lethal, with cora^GD1405

(Gardiol and St Johnston, 2014)

lethal, with Hsap\SMN1^UAS.cMa

(Borg and Cauchi, 2013)

lethal, with LamC^R564P.UAS

(Walker et al., 2023)

lethal, with Pi3K68D^UAS.EGFP

(Hauswirth et al., 2018)

lethal - all die before end of first instar larval stage, with EcR^{B1-ΔC655.F645A.UAS}

(Liu et al., 2010)

lethal - all die before end of P-stage, with LamC^K521Q.UAS

(Shaw et al., 2022)

lethal - all die before end of P-stage, with LamC^R205W.UAS

(Shaw et al., 2022)

lethal - all die before end of P-stage, with LamC^R237P.UAS

(Shaw et al., 2022)

lethal - all die before end of P-stage, with LamC^S37L.UAS

(Shaw et al., 2022)

lethal - all die before end of P-stage, with LamC^ΔK47.UAS

(Shaw et al., 2022)

lethal - all die before end of P-stage, with Madm^GD7155, Scer\GAL4^elav-C155

(Mushtaq et al., 2022)

majority die during P-stage, with cbc^HMC06558

(Schmidt et al., 2022)

partially lethal, with koi^{UAS.PA.Tag:V5}

(Tan et al., 2018)

partially lethal | heat sensitive, with Gem3^ΔN.UAS

(Cauchi et al., 2008)

partially lethal - majority die, with bor^R534W.UAS

(Harel et al., 2016)

partially lethal - majority die, with cbc^HMC06558

(Schmidt et al., 2022)

partially lethal - majority die, with LamC^G489V.UAS

(Shaw et al., 2022, Dialynas et al., 2012)

partially lethal - majority die, with LamC^K521W.UAS

(Walker et al., 2023)

partially lethal - majority die, with LamC^L74R.UAS

(Shaw et al., 2022)

partially lethal - majority die, with LamC^M553R.UAS

(Dialynas et al., 2012)

partially lethal - majority die, with LamC^N496I.UAS

(Dialynas et al., 2012)

partially lethal - majority die, with LamC^R564P.UAS

(Mohar et al., 2025, Shaw et al., 2022)

partially lethal - majority die, with LamC^V528P.UAS

(Dialynas et al., 2012)

partially lethal - majority die, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

short lived, with Torsin^RNAi.UAS.WIZ

(Nguyen et al., 2016)

some die during first instar larval stage, with EcR^{B1-ΔC655.F645A.UAS}

(Liu et al., 2010)

some die during P-stage, with LamC^G489V.UAS

(Dialynas et al., 2015)

some die during P-stage, with LamC^K521W.UAS

(Walker et al., 2023)

some die during P-stage, with LamC^M553R.UAS

(Dialynas et al., 2015)

some die during P-stage, with LamC^N496I.UAS

(Dialynas et al., 2015)

some die during P-stage, with LamC^R564P.UAS

(Mohar et al., 2025, Walker et al., 2023)

some die during P-stage, with LamC^V528P.UAS

(Dialynas et al., 2015)

some die during P-stage, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2015)

viable, with bor^WT.UAS

(Harel et al., 2016)

viable, with COX5B^GD6659

(Kemppainen et al., 2014)

viable, with COX6B^GD13061

(Kemppainen et al., 2014)

viable, with Gem3^GD17221

(Borg and Cauchi, 2013)

viable, with LamC^UAS.cSa

(Walker et al., 2023, Shaw et al., 2022, Dialynas et al., 2012, Dialynas et al., 2010)

viable, with LamC^ΔN.UAS

(Shaw et al., 2022)

viable, with Madm^GD7155

(Mushtaq et al., 2022)

viable, with rig^NIG.11171R

(Borg and Cauchi, 2013)

viable, with Syx18^UAS.cGa

(Gorczyca et al., 2007)

viable, with Tbce^RNAi.UAS.cJa

(Jin et al., 2009)

visible, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

Phenotype Manifest In

actin cytoskeleton | larval stage, with LamC^G489V.UAS

(Dialynas et al., 2015)

actin cytoskeleton | larval stage, with LamC^M553R.UAS

(Dialynas et al., 2015)

actin cytoskeleton | larval stage, with LamC^N496I.UAS

(Dialynas et al., 2015)

actin cytoskeleton | larval stage, with LamC^V528P.UAS

(Dialynas et al., 2015)

actin cytoskeleton | larval stage, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2015)

bouton, with Arp2^GD14716

(Nahm et al., 2010)

bouton, with Arp3^GD12273

(Nahm et al., 2010)

bouton, with Cdc42^KK108698

(Nahm et al., 2010)

bouton, with Cip4^NIG.15015R

(Nahm et al., 2010)

bouton, with fz2^{C.UAS.NLS.Tag:MYC}

(Ataman et al., 2006)

bouton, with fz2^UAS.cCa

(Packard et al., 2002)

bouton, with Grip^RNAi.UAS

(Ataman et al., 2006)

bouton, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Mozer and Sandstrom, 2012)

bouton | third instar larval stage, with Mad^GD4121

(Fuentes-Medel et al., 2012)

bouton | third instar larval stage, with put^GD49

(Fuentes-Medel et al., 2012)

bouton | third instar larval stage, with put^KK102676

(Fuentes-Medel et al., 2012)

cytoplasmic microtubule | third instar larval stage, with Hsap\MAPT^V337M.UAS

(Mao et al., 2017)

cytoplasmic microtubule | third instar larval stage | conditional, with HDAC6^UAS.cDa

(Mao et al., 2017)

embryonic/larval hypodermal muscle | larval stage, with klar^JF02944

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with koi^HMS02172

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^G489V.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^K521Q.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^L74R.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^R205W.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^R237P.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^R564P.UAS

(Mohar et al., 2025, Walker et al., 2023, Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^S37L.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^ΔK47.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with LamC^ΔN.UAS

(Shaw et al., 2022)

embryonic/larval hypodermal muscle | larval stage, with Msp300^HMS00632

(Shaw et al., 2022)

embryonic/larval hypodermal muscle cell | larval stage, with LamC^G489V.UAS

(Dialynas et al., 2015)

embryonic/larval hypodermal muscle cell | larval stage, with LamC^K521W.UAS

(Walker et al., 2023)

embryonic/larval hypodermal muscle cell | larval stage, with LamC^M553R.UAS

(Dialynas et al., 2015)

embryonic/larval hypodermal muscle cell | larval stage, with LamC^N496I.UAS

(Dialynas et al., 2015)

embryonic/larval hypodermal muscle cell | larval stage, with LamC^V528P.UAS

(Dialynas et al., 2015)

embryonic/larval hypodermal muscle cell | larval stage, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2015)

embryonic/larval hypodermal muscle cell | third instar larval stage, with koi^{UAS.PA.Tag:V5}

(Tan et al., 2018)

embryonic/larval neuromuscular junction, with baz^GD1384

(Ramachandran et al., 2009)

embryonic/larval neuromuscular junction, with baz^RNAi.cRa.UAS

(Ramachandran et al., 2009)

embryonic/larval neuromuscular junction, with Syx18^UAS.cGa

(Gorczyca et al., 2007)

embryonic/larval neuromuscular junction, with Tbce^RNAi.UAS.cJa

(Jin et al., 2009)

embryonic/larval neuromuscular junction, with Tbce^UAS.cJa

(Jin et al., 2009)

embryonic/larval neuromuscular junction | larval stage, with DCAF12^UAS.cPa

(Patrón et al., 2019)

embryonic/larval neuromuscular junction | larval stage, with Madm^GD7155, Scer\GAL4^elav-C155

(Mushtaq et al., 2022)

embryonic/larval neuromuscular junction | larval stage, with Pi3K68D^AH1, Pi3K68D^UAS.EGFP

(Hauswirth et al., 2018)

embryonic/larval neuromuscular junction | larval stage, with Pi3K68D^HMS01296, Scer\GAL4^sca.PU

(Hauswirth et al., 2018)

embryonic/larval neuromuscular junction | larval stage, with Pi3K68D^UAS.EGFP

(Hauswirth et al., 2018)

embryonic/larval neuromuscular junction | larval stage, with Rab11^GD11761

(Hauswirth et al., 2018)

embryonic/larval neuromuscular junction | third instar larval stage, with Alk::Hsap\NPM1^UAS.act

(Rohrbough et al., 2013)

embryonic/larval neuromuscular junction | third instar larval stage, with Csk^UAS.YFP, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC

(Spring et al., 2016)

embryonic/larval neuromuscular junction | third instar larval stage, with GluRIIC^RNAi.UAS.cBa, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC

(Spring et al., 2016)

embryonic/larval neuromuscular junction | third instar larval stage, with Mad^GD4121

(Fuentes-Medel et al., 2012)

embryonic/larval neuromuscular junction | third instar larval stage, with nanos^{αTub84B.3'UTR.UAS}

(Menon et al., 2009)

embryonic/larval neuromuscular junction | third instar larval stage, with Nlg2^UAS.cSa

(Chen et al., 2012)

embryonic/larval neuromuscular junction | third instar larval stage, with put^GD49

(Fuentes-Medel et al., 2012)

embryonic/larval neuromuscular junction | third instar larval stage, with put^KK102676

(Fuentes-Medel et al., 2012)

endoplasmic reticulum, with Vap33^T48I.UAS

(Chen et al., 2010)

ISN innervated muscle cell of A1-7 | larval stage, with Sod1^GD7385

(Peng et al., 2019)

larval muscle cell, with DCAF12^UAS.cPa

(Patrón et al., 2019)

larval somatic muscle, with Cul4^KK101901

(Patrón et al., 2019)

larval somatic muscle, with DCAF12^UAS.cPa

(Patrón et al., 2019)

larval somatic muscle | larval stage, with Nuak^E197K.UAS

(Zhao et al., 2023)

larval somatic muscle | larval stage, with Nuak^JF02162

(Zhao et al., 2023)

larval somatic muscle | larval stage, with Nuak^K99R.UAS

(Zhao et al., 2023)

larval somatic muscle | larval stage, with Nuak^T226A.UAS

(Zhao et al., 2023)

larval somatic muscle cell, with atl^UAS.cLa

(Lee et al., 2009)

larval somatic muscle cell, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

larval somatic muscle cell, with Pi3K68D^{KDΔ21.UAS.mCherry}

(Hauswirth et al., 2018)

larval somatic muscle cell, with Pi3K68D^UAS.EGFP

(Hauswirth et al., 2018)

larval somatic muscle cell | larval stage, with nsl1^NIG.4699R

(Lone et al., 2010)

larval somatic muscle cell | third instar larval stage, with bor^R534W.UAS

(Harel et al., 2016)

larval somatic muscle cell | third instar larval stage, with bor^WT.UAS

(Harel et al., 2016)

larval somatic muscle cell | third instar larval stage, with Hsap\MAPT^V337M.UAS

(Mao et al., 2017)

larval somatic muscle cell | third instar larval stage, with TER94^A229E.UAS

(Johnson et al., 2015)

larval somatic muscle cell | third instar larval stage, with TER94^GD9777

(Johnson et al., 2015)

larval somatic muscle cell | third instar larval stage, with TER94^R152H.UAS

(Johnson et al., 2015)

larval somatic muscle cell | third instar larval stage, with TER94^R188Q.UAS

(Johnson et al., 2015)

larval somatic muscle cell | third instar larval stage | conditional, with HDAC6^UAS.cDa

(Mao et al., 2017)

leg, with LamC^M553R.UAS

(Dialynas et al., 2012)

leg, with LamC^N496I.UAS

(Dialynas et al., 2012)

leg, with LamC^V528P.UAS

(Dialynas et al., 2012)

leg disc, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

lysosome | third instar larval stage, with TER94^A229E.UAS

(Johnson et al., 2015)

lysosome | third instar larval stage, with TER94^GD9777

(Johnson et al., 2015)

lysosome | third instar larval stage, with TER94^R152H.UAS

(Johnson et al., 2015)

lysosome | third instar larval stage, with TER94^R188Q.UAS

(Johnson et al., 2015)

metathoracic femur, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

metathoracic metatarsus, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

metathoracic tarsal segment, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

metathoracic tibia, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2010)

microtubule, with Hsap\MAPT^UAS.cWa

(Xiong et al., 2013)

microtubule, with Hsap\MAPT^V337M.UAS

(Xiong et al., 2013)

microtubule, with Kat60^UAS.cMa

(Mao et al., 2014)

microtubule, with spas^UAS.cTa

(Mao et al., 2014, Jin et al., 2009)

microtubule, with Tbce^RNAi.UAS.cJa

(Jin et al., 2009)

microtubule, with Tbce^UAS.cJa

(Jin et al., 2009)

microtubule & embryonic/larval somatic muscle, with atl^R192Q.UAS

(Lee et al., 2009)

microtubule & embryonic/larval somatic muscle, with atl^UAS.cLa

(Lee et al., 2009)

microtubule | larval stage, with klar^JF02944

(Shaw et al., 2022)

microtubule | larval stage, with koi^HMS02172

(Shaw et al., 2022)

microtubule | larval stage, with LamC^K521Q.UAS

(Shaw et al., 2022)

microtubule | larval stage, with LamC^ΔK47.UAS

(Shaw et al., 2022)

microtubule | larval stage, with Msp300^HMS00632

(Shaw et al., 2022)

microtubule | third instar larval stage, with koi^{UAS.PA.Tag:V5}

(Tan et al., 2018)

mitochondrion & bouton, with fz2^UAS.cCa

(Packard et al., 2002)

mitochondrion | third instar larval stage, with bor^R534W.UAS

(Harel et al., 2016)

mitochondrion | third instar larval stage, with bor^WT.UAS

(Harel et al., 2016)

mitochondrion | third instar larval stage, with TER94^GD9777

(Johnson et al., 2015)

neuromuscular junction, with Arp2^GD14716

(Nahm et al., 2010)

neuromuscular junction, with Arp3^GD12273

(Nahm et al., 2010)

neuromuscular junction, with Cdc42^KK108698

(Nahm et al., 2010)

neuromuscular junction, with Cip4^NIG.15015R

(Nahm et al., 2010)

neuromuscular junction, with fz2^{C.UAS.NLS.Tag:MYC}

(Ataman et al., 2006)

neuromuscular junction, with fz2^UAS.cCa

(Packard et al., 2002)

neuromuscular junction, with WASp^GD1559

(Nahm et al., 2010)

neuromuscular junction | third instar larval stage, with LanA^9-32, LanA^GD6022

(Tsai et al., 2012)

neuromuscular junction | third instar larval stage, with LanA^C01-190

(Tsai et al., 2012)

NMJ bouton, with atl^R192Q.UAS

(Lee et al., 2009)

NMJ bouton, with baz^GD1384

(Ramachandran et al., 2009)

NMJ bouton, with baz^RNAi.cRa.UAS

(Ramachandran et al., 2009)

NMJ bouton, with gbb^UAS.GFP

(Nahm et al., 2010)

NMJ bouton, with Hsap\TOR1A^ΔE.UAS

(Koh et al., 2004)

NMJ bouton, with Pten^{RNAi.Exel.UAS}

(Ramachandran et al., 2009)

NMJ bouton, with Pten^{RNAi.Exel.UAS}, Pten^dj189

(Ramachandran et al., 2009)

NMJ bouton, with Syx18^UAS.cGa

(Gorczyca et al., 2007)

NMJ bouton, with Tbce^RNAi.UAS.cJa

(Jin et al., 2009)

NMJ bouton, with Tbce^UAS.cJa

(Jin et al., 2009)

NMJ bouton, with WASp^GD1559

(Nahm et al., 2010)

NMJ bouton | increased number | larval stage, with DCAF12^UAS.cPa

(Patrón et al., 2019)

NMJ bouton | increased number | third instar larval stage, with rols^HMC04426

(Guo et al., 2019)

NMJ bouton | increased number | third instar larval stage, with rols^HMJ22326

(Guo et al., 2019)

NMJ bouton | larval stage, with Adcy1^GD3358

(Tsai et al., 2012)

NMJ bouton | larval stage, with Adcy1^KK109441

(Tsai et al., 2012)

NMJ bouton | larval stage, with Sac1^GD2238

(Forrest et al., 2013)

NMJ bouton | larval stage, with Vap33^GD3990

(Forrest et al., 2013)

NMJ bouton | third instar larval stage, with gbb^UAS.GFP

(Nahm et al., 2010)

NMJ bouton | third instar larval stage, with Kat60^UAS.cMa

(Mao et al., 2014)

NMJ bouton | third instar larval stage, with Nlg2^UAS.cSa

(Chen et al., 2012)

NMJ bouton | third instar larval stage, with Torsin^E177Q.UAS

(Jokhi et al., 2013)

NMJ bouton | third instar larval stage, with Torsin^KK107949

(Jokhi et al., 2013)

NMJ bouton | third instar larval stage, with Torsin^ΔE.UAS

(Jokhi et al., 2013)

nucleus, with LamC^ΔN.UAS.cSa

(Zwerger et al., 2013, Dialynas et al., 2010)

nucleus, with Vap33^UAS.cPa

(Sanhueza et al., 2014)

nucleus, with Vap33^V260I.UAS

(Sanhueza et al., 2014)

nucleus | larval stage, with DCAF12^UAS.cPa

(Patrón et al., 2019)

nucleus | larval stage, with LamC^G489V.UAS

(Dialynas et al., 2015)

nucleus | larval stage, with LamC^K521W.UAS

(Walker et al., 2023)

nucleus | larval stage, with LamC^M553R.UAS

(Dialynas et al., 2015)

nucleus | larval stage, with LamC^N496I.UAS

(Dialynas et al., 2015)

nucleus | larval stage, with LamC^V528P.UAS

(Dialynas et al., 2015)

nucleus | larval stage, with LamC^ΔN.UAS.cSa

(Dialynas et al., 2015)

nucleus | third instar larval stage, with koi^{UAS.PA.Tag:V5}

(Tan et al., 2018)

postsynaptic membrane, with fz2^UAS.cCa

(Packard et al., 2002)

pupa, with LamC^M553R.UAS

(Dialynas et al., 2012)

pupa, with LamC^N496I.UAS

(Dialynas et al., 2012)

pupa, with LamC^V528P.UAS

(Dialynas et al., 2012)

somatic muscle cell, with Vap33^UAS.cPa

(Sanhueza et al., 2014)

somatic muscle cell, with Vap33^V260I.UAS

(Sanhueza et al., 2014)

subsynaptic reticulum | ectopic, with Syx18^UAS.cGa

(Gorczyca et al., 2007)

synapse, with Arp2^GD14716

(Nahm et al., 2010)

synapse, with Arp3^GD12273

(Nahm et al., 2010)

synapse, with BacA\p35^UAS.cHa

(Liu et al., 2010)

synapse, with Diap1^{UAS.Tag:MYC.cBa}

(Liu et al., 2010)

synapse, with Pi3K92E^{D954A.UAS.Tag:MYC}

(Mozer and Sandstrom, 2012)

synapse, with Scer\UBP2^UAS.cDa

(Liu et al., 2010)

synapse, with Vap33^UAS.cPa

(Sanhueza et al., 2014)

synapse, with Vap33^V260I.UAS

(Sanhueza et al., 2014)

synapse | larval stage, with Madm^GD7155, Scer\GAL4^elav-C155

(Mushtaq et al., 2022)

t-bar, with fz2^UAS.cCa

(Packard et al., 2002)

type I bouton | larval stage, with Torsin^RNAi.UAS.WIZ

(Nguyen et al., 2016)

type I bouton | larval stage, with Torsin^UAS.cKa

(Nguyen et al., 2016)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

LamC^R564P.UAS, Scer\GAL4^C57 has increased mortality during development phenotype, enhanceable by Dad^P455R

(Mohar et al., 2025)

LamC^R564P.UAS, Scer\GAL4^C57 has decreased rate of larval locomotory behavior phenotype, enhanceable by Dad^P455R

(Mohar et al., 2025)

Scer\GAL4^C57, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC, cac^KK101478 has abnormal neurophysiology phenotype, enhanceable by GluRIIC^RNAi.UAS.cBa, Scer\GAL4^C57, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC

(Brusich et al., 2015)

NOT Enhanced by

Statement

Reference

DCAF12^UAS.cPa, Scer\GAL4^C57 has abnormal size | larval stage phenotype, non-enhanceable by pic^EY01408

(Patrón et al., 2019)

Suppressed by

Statement

Reference

LamC^R564P.UAS, Scer\GAL4^C57 has decreased rate of larval locomotory behavior phenotype, suppressible | partially by Dad^UAS.cTa, Scer\GAL4^C57

(Mohar et al., 2025)

LamC^R564P.UAS, Scer\GAL4^C57 has abnormal behavior | larval stage phenotype, suppressible by Dad^UAS.cTa, Scer\GAL4^C57

(Mohar et al., 2025)

LamC^R564P.UAS, Scer\GAL4^C57 has decreased size | larval stage phenotype, suppressible | partially by Dad^UAS.cTa, Scer\GAL4^C57

(Mohar et al., 2025)

DCAF12^UAS.cPa, Scer\GAL4^C57 has abnormal neurophysiology | larval stage phenotype, suppressible | partially by Cul4[+]/Cul4^11L

(Patrón et al., 2019)

Kat60^UAS.cMa, Scer\GAL4^C57 has abnormal neuroanatomy | third instar larval stage phenotype, suppressible by HDAC6^UAS.cDa, Scer\GAL4^C57

(Mao et al., 2014)

Cip4^NIG.15015R, Scer\GAL4^C57 has abnormal neuroanatomy phenotype, suppressible by wit^A12/wit[+]

(Nahm et al., 2010)

Scer\GAL4^C57, WASp^GD1559 has abnormal neuroanatomy phenotype, suppressible by wit^A12/wit[+]

(Nahm et al., 2010)

NOT suppressed by

Statement

Reference

DCAF12^UAS.cPa, Scer\GAL4^C57 has abnormal size | larval stage phenotype, non-suppressible by pic^EY01408

(Patrón et al., 2019)

Enhancer of

Statement

Reference

Scer\GAL4^C57/LamC^R564P.UAS is an enhancer of decreased rate of larval locomotory behavior phenotype of Dad^P455R

(Mohar et al., 2025)

Mp^{ES.UAS.Tag:SS(wg)}/Scer\GAL4^C57 is an enhancer of abnormal neurophysiology | larval stage phenotype of Pi3K68D^AH1

(Hauswirth et al., 2018)

Scer\GAL4^sca.PC, GluRIIC^RNAi.UAS.cBa, Scer\GAL4^elav-C155, Scer\GAL4^C57 is an enhancer of abnormal neurophysiology phenotype of Scer\GAL4^C57, Scer\GAL4^elav-C155, Scer\GAL4^sca.PC, cac^KK101478

(Brusich et al., 2015)

NOT Enhancer of

Statement

Reference

gsb^491.RNAi.UAS/Scer\GAL4^C57 is a non-enhancer of abnormal neurophysiology phenotype of GluRIIA^SP16

(Marie et al., 2010)

Cip4^NIG.15015R/Scer\GAL4^C57 is a non-enhancer of abnormal neuroanatomy phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

WASp^GD1559/Scer\GAL4^C57 is a non-enhancer of abnormal neuroanatomy phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

Scer\GAL4^C57/Eph^DN.UAS is a non-enhancer of abnormal neurophysiology | third instar larval stage | recessive phenotype of GluRIIA^SP16

(Frank et al., 2009)

Suppressor of

Statement

Reference

Dad^UAS.cTa, Scer\GAL4^C57 is a suppressor | partially of decreased rate of larval locomotory behavior phenotype of LamC^R564P.UAS, Scer\GAL4^C57

(Mohar et al., 2025)

Dad^UAS.cTa, Scer\GAL4^C57 is a suppressor of abnormal behavior | larval stage phenotype of LamC^R564P.UAS, Scer\GAL4^C57

(Mohar et al., 2025)

Dad^UAS.cTa, Scer\GAL4^C57 is a suppressor | partially of decreased size | larval stage phenotype of LamC^R564P.UAS, Scer\GAL4^C57

(Mohar et al., 2025)

tsr^S3A.UAS.EGFP/Scer\GAL4^C57 is a suppressor of abnormal neurophysiology | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^S3E.UAS.EGFP/Scer\GAL4^C57 is a suppressor | partially of abnormal neurophysiology | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^S3A.UAS.EGFP/Scer\GAL4^C57 is a suppressor of decreased rate of larval locomotory behavior phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^UAS.EGFP/Scer\GAL4^C57 is a suppressor of decreased rate of larval locomotory behavior phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^UAS.EGFP/Scer\GAL4^C57 is a suppressor of abnormal neurophysiology | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^S3A.UAS.EGFP/Scer\GAL4^C57 is a suppressor | partially of abnormal neuroanatomy | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^UAS.EGFP/Scer\GAL4^C57 is a suppressor | partially of abnormal neuroanatomy | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

Hsap\SOD1^UAS.cWa/Scer\GAL4^C57 is a suppressor of abnormal neurophysiology | larval stage phenotype of Eaat1^hypo

(Peng et al., 2019)

Hsap\SOD1^UAS.cWa/Scer\GAL4^C57 is a suppressor | partially of abnormal locomotor behavior | larval stage phenotype of Eaat1^hypo

(Peng et al., 2019)

Hsap\SOD1^UAS.cWa/Scer\GAL4^C57 is a suppressor of abnormal neuroanatomy | larval stage phenotype of Eaat1^hypo

(Peng et al., 2019)

HDAC6^UAS.cDa, Scer\GAL4^C57 is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Kat60^UAS.cMa, Scer\GAL4^C57

(Mao et al., 2014)

LanA^C01-190/Scer\GAL4^C57 is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of Sh²¹, eag¹

(Tsai et al., 2012)

LanA^C01-190/Scer\GAL4^C57 is a suppressor of abnormal neuroanatomy | third instar larval stage | heat sensitive phenotype of para^ts1

(Tsai et al., 2012)

Hsap\ELP3^UAS.cMa/Scer\GAL4^C57 is a suppressor of abnormal neurophysiology | third instar larval stage phenotype of Elp3^Δ3/Elp3^Δ4

(Miśkiewicz et al., 2011)

gbb^UAS.GFP/Scer\GAL4^C57 is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of RhoGAP92B¹/RhoGAP92B²

(Nahm et al., 2010)

Rac1^N17.UAS/Scer\GAL4^C57 is a suppressor of abnormal neuroanatomy | larval stage phenotype of Vps35^EY14200/Df(2R)ED3952

(Korolchuk et al., 2007)

NOT Suppressor of

Statement

Reference

tsr^S3E.UAS.EGFP/Scer\GAL4^C57 is a non-suppressor of decreased rate of larval locomotory behavior phenotype of Nlg2^KO70

(Sun et al., 2023)

gsb^491.RNAi.UAS/Scer\GAL4^C57 is a non-suppressor of abnormal neurophysiology phenotype of GluRIIA^SP16

(Marie et al., 2010)

Cip4^NIG.15015R/Scer\GAL4^C57 is a non-suppressor of abnormal neuroanatomy phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

WASp^GD1559/Scer\GAL4^C57 is a non-suppressor of abnormal neuroanatomy phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

Scer\GAL4^C57/Eph^DN.UAS is a non-suppressor of abnormal neurophysiology | recessive | third instar larval stage phenotype of GluRIIA^SP16

(Frank et al., 2009)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

DCAF12^UAS.cPa, Scer\GAL4^C57 has NMJ bouton | larval stage | increased number phenotype, non-enhanceable by pic^EY01408

(Patrón et al., 2019)

DCAF12^UAS.cPa, Scer\GAL4^C57 has larval somatic muscle phenotype, non-enhanceable by pic^EY01408

(Patrón et al., 2019)

Suppressed by

Statement

Reference

LamC^R564P.UAS, Scer\GAL4^C57 has embryonic/larval hypodermal muscle | larval stage phenotype, suppressible | partially by Dad^UAS.cTa, Scer\GAL4^C57

(Mohar et al., 2025)

DCAF12^UAS.cPa, Scer\GAL4^C57 has NMJ bouton | increased number | larval stage phenotype, suppressible by Cul4^11L

(Patrón et al., 2019)

DCAF12^UAS.cPa, Scer\GAL4^C57 has larval somatic muscle phenotype, suppressible | partially by Cul4^11L

(Patrón et al., 2019)

DCAF12^UAS.cPa, Scer\GAL4^C57 has embryonic/larval neuromuscular junction phenotype, suppressible | partially by Cul4[+]/Cul4^11L

(Patrón et al., 2019)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has larval somatic muscle cell | third instar larval stage phenotype, suppressible by αTub84B^K40Q/αTub84B^K40Q

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has cytoplasmic microtubule | third instar larval stage phenotype, suppressible by αTub84B^K40Q/αTub84B^K40Q

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has larval somatic muscle cell | third instar larval stage phenotype, suppressible | partially by αTub84B^K40R/αTub84B^K40R

(Mao et al., 2017)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has cytoplasmic microtubule | third instar larval stage phenotype, suppressible | partially by αTub84B^K40R/αTub84B^K40R

(Mao et al., 2017)

Scer\GAL4^C57, TER94^GD9777 has larval somatic muscle cell | third instar larval stage phenotype, suppressible by Hsap\VCP^UAS.cCa, Scer\GAL4^C57

(Johnson et al., 2015)

Scer\GAL4^C57, TER94^GD9777 has lysosome | third instar larval stage phenotype, suppressible by Hsap\VCP^UAS.cCa, Scer\GAL4^C57

(Johnson et al., 2015)

Kat60^UAS.cMa, Scer\GAL4^C57 has NMJ bouton | third instar larval stage phenotype, suppressible by HDAC6^UAS.cDa, Scer\GAL4^C57

(Mao et al., 2014)

Kat60^UAS.cMa, Scer\GAL4^C57 has microtubule phenotype, suppressible by HDAC6^UAS.cDa, Scer\GAL4^C57

(Mao et al., 2014)

Hsap\MAPT^UAS.cWa, Scer\GAL4^C57 has microtubule phenotype, suppressible by HDAC6^KO

(Xiong et al., 2013)

Hsap\MAPT^UAS.cWa, Scer\GAL4^C57 has microtubule phenotype, suppressible by Df(1)ED7294/HDAC6^KO

(Xiong et al., 2013)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has microtubule phenotype, suppressible by HDAC6^KO

(Xiong et al., 2013)

Hsap\MAPT^V337M.UAS, Scer\GAL4^C57 has microtubule phenotype, suppressible by Df(1)ED7294/HDAC6^KO

(Xiong et al., 2013)

Cip4^NIG.15015R, Scer\GAL4^C57 has neuromuscular junction phenotype, suppressible by wit^A12/wit[+]

(Nahm et al., 2010)

Cip4^NIG.15015R, Scer\GAL4^C57 has bouton phenotype, suppressible by wit^A12/wit[+]

(Nahm et al., 2010)

Scer\GAL4^C57, WASp^GD1559 has neuromuscular junction phenotype, suppressible by wit^A12/wit[+]

(Nahm et al., 2010)

Scer\GAL4^C57, WASp^GD1559 has bouton phenotype, suppressible by wit^A12/wit[+]

(Nahm et al., 2010)

Scer\GAL4^C57, Tbce^UAS.cJa has microtubule phenotype, suppressible | partially by Scer\GAL4^C57

(Jin et al., 2009)

Scer\GAL4^C57, atl^UAS.cLa has larval somatic muscle cell phenotype, suppressible by spas^5.75/spas^5.75

(Lee et al., 2009)

NOT suppressed by

Statement

Reference

DCAF12^UAS.cPa, Scer\GAL4^C57 has nucleus | larval stage phenotype, non-suppressible by Cul4^11L

(Patrón et al., 2019)

DCAF12^UAS.cPa, Scer\GAL4^C57 has NMJ bouton | increased number | larval stage phenotype, non-suppressible by pic^EY01408

(Patrón et al., 2019)

DCAF12^UAS.cPa, Scer\GAL4^C57 has larval somatic muscle phenotype, non-suppressible by pic^EY01408

(Patrón et al., 2019)

DCAF12^UAS.cPa, Scer\GAL4^C57 has larval muscle cell phenotype, non-suppressible by Cul4^11L

(Patrón et al., 2019)

Scer\GAL4^C57, spas^UAS.cTa has microtubule phenotype, non-suppressible by HDAC6^KO

(Mao et al., 2014)

Scer\GAL4^C57, spas^UAS.cTa has microtubule phenotype, non-suppressible by HDAC6^UAS.cDa, Scer\GAL4^C57

(Mao et al., 2014)

Scer\GAL4^C57, Syx18^UAS.cGa has subsynaptic reticulum | ectopic phenotype, non-suppressible by dlg1⁷

(Gorczyca et al., 2007)

Enhancer of

Statement

Reference

Mp^{ES.UAS.Tag:SS(wg)}/Scer\GAL4^C57 is an enhancer of embryonic/larval neuromuscular junction | larval stage phenotype of Pi3K68D^AH1

(Hauswirth et al., 2018)

NOT Enhancer of

Statement

Reference

gsb^491.RNAi.UAS/Scer\GAL4^C57 is a non-enhancer of neuromuscular junction phenotype of GluRIIA^SP16

(Marie et al., 2010)

Cip4^NIG.15015R/Scer\GAL4^C57 is a non-enhancer of synapse phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

Cip4^NIG.15015R/Scer\GAL4^C57 is a non-enhancer of neuromuscular junction phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

WASp^GD1559/Scer\GAL4^C57 is a non-enhancer of synapse phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

WASp^GD1559/Scer\GAL4^C57 is a non-enhancer of neuromuscular junction phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

Scer\GAL4^C57/Eph^DN.UAS is a non-enhancer of embryonic/larval neuromuscular junction phenotype of GluRIIA^SP16

(Frank et al., 2009)

Suppressor of

Statement

Reference

Dad^UAS.cTa, Scer\GAL4^C57 is a suppressor | partially of embryonic/larval hypodermal muscle | larval stage phenotype of LamC^R564P.UAS, Scer\GAL4^C57

(Mohar et al., 2025)

tsr^UAS.EGFP/Scer\GAL4^C57 is a suppressor | partially of NMJ bouton | larval stage | decreased number phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^S3A.UAS.EGFP/Scer\GAL4^C57 is a suppressor | partially of filamentous actin | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^S3A.UAS.EGFP/Scer\GAL4^C57 is a suppressor of NMJ bouton | larval stage | decreased number phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^S3A.UAS.EGFP/Scer\GAL4^C57 is a suppressor | partially of embryonic/larval neuromuscular junction | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^UAS.EGFP/Scer\GAL4^C57 is a suppressor | partially of embryonic/larval neuromuscular junction | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

Hsap\SOD1^UAS.cWa/Scer\GAL4^C57 is a suppressor of embryonic/larval neuromuscular junction | larval stage phenotype of Eaat1^hypo

(Peng et al., 2019)

Hsap\SOD1^UAS.cWa/Scer\GAL4^C57 is a suppressor of NMJ bouton | increased number | larval stage phenotype of Eaat1^hypo

(Peng et al., 2019)

Hsap\VCP^UAS.cCa, Scer\GAL4^C57 is a suppressor of larval somatic muscle cell | third instar larval stage phenotype of Scer\GAL4^C57, TER94^GD9777

(Johnson et al., 2015)

Hsap\VCP^UAS.cCa, Scer\GAL4^C57 is a suppressor of lysosome | third instar larval stage phenotype of Scer\GAL4^C57, TER94^GD9777

(Johnson et al., 2015)

HDAC6^UAS.cDa, Scer\GAL4^C57 is a suppressor of NMJ bouton | third instar larval stage phenotype of Kat60^UAS.cMa, Scer\GAL4^C57

(Mao et al., 2014)

HDAC6^UAS.cDa, Scer\GAL4^C57 is a suppressor of microtubule phenotype of Kat60^UAS.cMa, Scer\GAL4^C57

(Mao et al., 2014)

LanA^C01-190/Scer\GAL4^C57 is a suppressor of neuromuscular junction | third instar larval stage phenotype of Sh²¹, eag¹

(Tsai et al., 2012)

LanA^C01-190/Scer\GAL4^C57 is a suppressor of neuromuscular junction | third instar larval stage | heat sensitive phenotype of para^ts1

(Tsai et al., 2012)

gbb^UAS.GFP/Scer\GAL4^C57 is a suppressor of NMJ bouton | third instar larval stage phenotype of RhoGAP92B¹/RhoGAP92B²

(Nahm et al., 2010)

Scer\GAL4^C57 is a suppressor | partially of microtubule phenotype of Scer\GAL4^C57, Tbce^UAS.cJa

(Jin et al., 2009)

Rac1^N17.UAS/Scer\GAL4^C57 is a suppressor of NMJ bouton phenotype of Vps35^EY14200/Df(2R)ED3952

(Korolchuk et al., 2007)

Fas2^UAS.cAa/Scer\GAL4^C57 is a suppressor of NMJ bouton phenotype of Appl^d

(Ashley et al., 2005)

NOT Suppressor of

Statement

Reference

tsr^UAS.EGFP/Scer\GAL4^C57 is a non-suppressor of filamentous actin | larval stage phenotype of Nlg2^KO70

(Sun et al., 2023)

tsr^S3E.UAS.EGFP/Scer\GAL4^C57 is a non-suppressor of NMJ bouton | larval stage | decreased number phenotype of Nlg2^KO70

(Sun et al., 2023)

HDAC6^UAS.cDa, Scer\GAL4^C57 is a non-suppressor of microtubule phenotype of Scer\GAL4^C57, spas^UAS.cTa

(Mao et al., 2014)

gsb^491.RNAi.UAS/Scer\GAL4^C57 is a non-suppressor of neuromuscular junction phenotype of GluRIIA^SP16

(Marie et al., 2010)

Cip4^NIG.15015R/Scer\GAL4^C57 is a non-suppressor of synapse phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

Cip4^NIG.15015R/Scer\GAL4^C57 is a non-suppressor of neuromuscular junction phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

WASp^GD1559/Scer\GAL4^C57 is a non-suppressor of synapse phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

WASp^GD1559/Scer\GAL4^C57 is a non-suppressor of neuromuscular junction phenotype of wit^B11/wit^A12

(Nahm et al., 2010)

Scer\GAL4^C57/Eph^DN.UAS is a non-suppressor of embryonic/larval neuromuscular junction phenotype of GluRIIA^SP16

(Frank et al., 2009)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

rols^LA00796/Scer\GAL4^C57 rescues rols^HMC04426

(Guo et al., 2019)

rols^LA00796/Scer\GAL4^C57 rescues rols^HMJ22326

(Guo et al., 2019)

dbo^UAS.GFP/Scer\GAL4^C57 rescues dbo^c04604/dbo^henji-1

(Wang et al., 2016)

dbo^UAS.GFP/Scer\GAL4^C57 rescues dbo^henji-1

(Wang et al., 2016)

Past1^UAS.EGFP/Scer\GAL4^C57 rescues Past1^110-1/Past1^60-4

(Koles et al., 2015)

HDAC6^UAS.cDa/Scer\GAL4^C57 rescues HDAC6^KO

(Xiong et al., 2013)

Scer\GAL4^C57/HDAC6^H237A.UAS rescues HDAC6^KO

(Xiong et al., 2013)

Tbh^UAS.cMa/Scer\GAL4^C57 rescues Tbh^nM18

(Koon et al., 2011)

Nlg2^UAS.cSa/Scer\GAL4^C57 rescues Nlg2^GD962

(Sun et al., 2011)

nsl1^UAS.Tag:HA/Scer\GAL4^C57 rescues nsl1^NIG.4699R

(Lone et al., 2010)

RhoGAP92B^UAS.cNa/Scer\GAL4^C57 rescues RhoGAP92B¹/RhoGAP92B²

(Nahm et al., 2010)

Scer\GAL4^C57/Cip4^UAS.N.Tag:HA rescues Df(3L)ED4342/Cip4¹

(Nahm et al., 2010)

Cip4^{L145D.UAS.Tag:HA}/Scer\GAL4^C57 rescues Df(3L)ED4342/Cip4¹

(Nahm et al., 2010)

Gem3^UAS.cCa/Scer\GAL4^C57 rescues Gem3^ΔN.UAS

(Cauchi et al., 2008)

Scer\GAL4^elav.PLu/Scer\GAL4^C57, Vps35^EY14200 rescues Vps35^EY14200/Df(2R)ED3952

(Korolchuk et al., 2007)

Nsf2^UAS.cGa/Scer\GAL4^C57 rescues Nsf2¹⁵

(Golby et al., 2001)

Partially rescues

Abp1^UAS.cKa/Scer\GAL4^C57 partially rescues Df(3L)Exel6119/Abp1^KO

(Koch et al., 2014)

Sdhaf3^UAS.cNa/Scer\GAL4^C57 partially rescues Sdhaf3^null

(Na et al., 2014)

HDAC6^H664A.UAS/Scer\GAL4^C57 partially rescues HDAC6^KO

(Xiong et al., 2013)

Pdk1^UAS.Tag:FLAG/Scer\GAL4^C57 partially rescues Pdk1³³

(Cheng et al., 2011)

Scer\GAL4^RapGAP1-OK6, veli^UAS.Tag:FLAG, Scer\GAL4^C57 partially rescues veli⁶⁶

(Bachmann et al., 2010)

RhoGAP92B^R287A.UAS/Scer\GAL4^C57 partially rescues RhoGAP92B¹/RhoGAP92B²

(Nahm et al., 2010)

RhoGAP92B^{ΔBAR.UAS.GFP}/Scer\GAL4^C57 partially rescues RhoGAP92B¹/RhoGAP92B²

(Nahm et al., 2010)

twf^UAS.cWa/Scer\GAL4^C57 partially rescues twf¹¹⁰

(Wang et al., 2010)

atl^UAS.cLa/Scer\GAL4^C57 partially rescues Df(3R)Exel7357/atl²

(Lee et al., 2009)

Syx18^UAS.cGa/Scer\GAL4^C57 partially rescues Syx18^ex6

(Gorczyca et al., 2007)

Scer\GAL4^C57, Vps35^EY14200 partially rescues Vps35^EY14200/Df(2R)ED3952

(Korolchuk et al., 2007)

Gαs^UAS.cCa/Scer\GAL4^C57 partially rescues Gαs^B19

(Wolfgang et al., 2004)

dlg1^UAS.cBa/Scer\GAL4^C57 partially rescues dlg1¹⁴

(Budnik et al., 1996)

Fails to rescue

Rap1^UAS.Tag:MYC/Scer\GAL4^C57 fails to rescue Rap1^rvB1/Df(3L)ED4287

(Kim et al., 2024)

Arc1^UAS.cMb/Scer\GAL4^C57 fails to rescue Arc1^E8

(Keith et al., 2021)

DCAF12^UAS.cPa/Scer\GAL4^C57 fails to rescue DCAF12^Δ51

(Patrón et al., 2019)

egh^UAS.Tag:MYC/Scer\GAL4^C57 fails to rescue egh⁷

(Huang et al., 2018)

ari-1^UAS.cFa/Scer\GAL4^C57 fails to rescue ari-1^A

(Tan et al., 2018)

ari-1^UAS.cFa/Scer\GAL4^C57 fails to rescue ari-1^B

(Tan et al., 2018)

ari-1^UAS.cFa/Scer\GAL4^C57 fails to rescue ari-1^D

(Tan et al., 2018)

Tusp^UAS.cYa/Scer\GAL4^C57 fails to rescue Df(3R)Tusp-D

(Yoon et al., 2017)

Scer\GAL4^C57/Nlg4^UAS.cZa fails to rescue Nlg4^KO10

(Zhang et al., 2017)

spartin^UAS.Tag:HA/Scer\GAL4^C57 fails to rescue spartin¹/Df(3R)110

(Nahm et al., 2013)

HDAC6^{H237A.H664A.UAS}/Scer\GAL4^C57 fails to rescue HDAC6^KO

(Xiong et al., 2013)

Nlg2^UAS.cSa/Scer\GAL4^C57 fails to rescue Nlg2^CL2

(Chen et al., 2012)

Nlg2^UAS.cSa/Scer\GAL4^C57 fails to rescue Nlg2^KO70

(Chen et al., 2012)

Scer\GAL4^C57/Nf1^UAS.CFP fails to rescue Nf1^E2

(Tsai et al., 2012)

S6k^UAS.cCa/Scer\GAL4^C57 fails to rescue Df(3L)CH18/S6k^l-1

(Cheng et al., 2011)

Scer\GAL4^C57, sky^d03436 fails to rescue sky¹/sky^d03436

(Uytterhoeven et al., 2011)

Scer\GAL4^C57, sky^d03436 fails to rescue sky^d03436/sky²

(Uytterhoeven et al., 2011)

Cip4^{L436S.UAS.Tag:HA}/Scer\GAL4^C57 fails to rescue Df(3L)ED4342/Cip4¹

(Nahm et al., 2010)

Scer\GAL4^C57/Cip4^{W603K.UAS.Tag:HA} fails to rescue Df(3L)ED4342/Cip4¹

(Nahm et al., 2010)

nwk^UAS.cCa/Scer\GAL4^C57 fails to rescue nwk²

(Coyle et al., 2004)

comt^UAS.cGa/Scer\GAL4^C57 fails to rescue comt^clp

(Golby et al., 2001)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

32556

w^*; P{UAS-wah.HA}7; P{GawB}C57

52001

w^*; P{UAS-mito-HA-GFP.AP}2; P{GawB}C57/T(2;3)TSTL, CyO: TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

GAL4^BG57

Scer\GAL4^BG57

Scer\GAL4^C57

Name Synonyms

Secondary FlyBase IDs

FBal0058812

References (160)

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