FlyBase Allele Report: Dmel\dbo[UAS.GFP]

General Information

Symbol

Dmel\dbo^UAS.GFP

Species

D. melanogaster

Name

FlyBase ID

FBal0323172

Feature type

allele

Associated gene

Dmel\dbo

Associated Insertion(s)

Carried in Construct

P{UAS-GFP-dbo}

Key Links

Transgenic product class

wild_type

(Wang et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Wang et al., 2016)

Mutagen

in vitro construct

(Wang et al., 2016)

Progenitor genotype

Carried in construct

P{UAS-GFP-dbo}

Cytology

Description

UASt regulatory sequences drive expression of full-length dbo tagged with GFP.

(Wang et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dbo

Tagged with

GFP

green fluorescent protein

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

dbo^UAS.GFP/Scer\GAL4^C57 rescues dbo^c04604/dbo^henji-1

(Wang et al., 2016)

dbo^UAS.GFP/Scer\GAL4^C57 rescues dbo^henji-1

(Wang et al., 2016)

Fails to rescue

Scer\GAL4^elav.PU/dbo^UAS.GFP fails to rescue dbo^c04604/dbo^henji-1

(Wang et al., 2016)

Scer\GAL4^elav.PU/dbo^UAS.GFP fails to rescue dbo^henji-1

(Wang et al., 2016)

Comments

Expression of dbo^{Scer\UAS.T:Avic\GFP} under the control of Scer\GAL4^C57 (but not Scer\GAL4^elav.PU) rescues the increased number of satellite boutons seen in dbo^henji-1/dbo^henji-1 mutant larval neuromuscular junctions, and rescues the increased mEJP amplitude observed in dbo^henji-1/dbo^henji-1 and dbo^henji-1/dbo^c04604 mutant larval neuromuscular junctions.

(Wang et al., 2016)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

dbo^{Scer\UAS.T:Avic\GFP}

dbo^UAS.GFP

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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