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General Information
Symbol
Dmel\TbhUAS.cMa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Monastirioti
FlyBase ID
FBal0152163
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-Tβh
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of a 3.0kb EcoRI fragment containing the Tbh cDNA.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference
External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

The courtship conditioning defects seen in TbhnM18 males are rescued by expression of TbhScer\UAS.cMa under the control of Scer\GAL4Tdc2.PC.

Expression of TbhScer\UAS.cMa under the control of Scer\GAL4C57 rescues the increase locomotion elicited by food deprivation and the concurrent increase in neuromuscular junction synaptopods.

Expression of TbhScer\UAS.cMa in octopaminergic neurons under the control of Scer\GAL4Tdc2.PC rescues the drop in type II boutons and terminal branches seen in TbhnM18 mutant third instar larval neuromuscular junctions.

Expression of TbhScer\UAS.cMa under the control of Scer\GAL4Tdc2.PC reduces the aggression deficiency that is seen in TbhnM18 males; fighting latency is shortened and the frequencies of both lunging and high-intensity fighting (holding, boxing and tussling) are increased in the rescued flies in an aggression assay. Expression of TbhScer\UAS.cMa under the control of Scer\GAL4Tdc2.PC also effectively rescues the aggression phenotype of TbhnM18 females.

Expression of TbhScer\UAS.cMa under the control of either Scer\GAL4Tdc1.PC, Scer\GAL4c309, Scer\GAL4MJ286 or Scer\GAL4Cha.7.4 fails to rescue the reduced aggression phenotypes of TbhnM18 males.

Expression of TbhScer\UAS.cMa under the control of Scer\GAL4Tdc2.PC in the presence of the Scer\GAL80Cha.PK repressor (which inhibits Scer\GAL4 in the Cha expression domain) rescues the reduced aggression phenotypes of TbhnM18 males.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
TbhScer\UAS.cMa
TbhUAS.cMa
Name Synonyms
Saccharomyces cerevisiae UAS construct of Monastirioti
Secondary FlyBase IDs
    References (6)