FlyBase Allele Report: Dmel\ND-30[HMC02929]

General Information

Symbol

Dmel\ND-30^HMC02929

Species

D. melanogaster

Name

FlyBase ID

FBal0292201

Feature type

allele

Associated gene

Dmel\ND-30

Associated Insertion(s)

Carried in Construct

P{TRiP.HMC02929}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2010.12.1)

Mutagen

in vitro construct

(Ni et al., 2010.12.1)

Progenitor genotype

Carried in construct

P{TRiP.HMC02929}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2010.12.1)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMC02929

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates Parkinson's disease 6

modeled by Pink1^B9

(Fan et al., 2024)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal larval locomotory behavior, with Scer\GAL4^C57

(Mallik et al., 2025)

decreased size | larval stage, with Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

Phenotype Manifest In

axon | larval stage, with Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

larval ventral nerve cord, with Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

mitochondrion | decreased number | larval stage, with Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

motor neuron | larval stage, with Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

ND-30^HMC02929, Scer\GAL4^Toll-6-D42 has decreased size phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

Phenotype Manifest In

Suppressed by

Statement

Reference

ND-30^HMC02929, Scer\GAL4^Toll-6-D42 has mitochondrion | larval stage | decreased number phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

ND-30^HMC02929, Scer\GAL4^Toll-6-D42 has axon | larval stage phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

ND-30^HMC02929, Scer\GAL4^Toll-6-D42 has motor neuron | larval stage phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

ND-30^HMC02929, Scer\GAL4^Toll-6-D42 has larval ventral nerve cord phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^Toll-6-D42

(Mallik et al., 2025)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

44535

y¹ v¹; P{TRiP.HMC02929}attP40

NIG-Fly

HMC02929

y¹ v¹; P{TRiP.HMC02929}attP40

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ND-30^HMC02929

NDUFS3^HMC02929

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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