Expression of Sod2Scer\UAS.cMa under the control of Scer\GAL4da.PU suppresses the age-dependent loss of rhabdomeres and partially suppresses the age-dependent locomotor defect seen in YME1Ldel homozygotes.
The larval locomotor deficit, very low adult eclosion rate as well as the mitochondrial morphology defects in adult indirect flight muscles (enlarged clustered mitochondria) characteristic for animals expressing cluGD13926 under the control of Scer\GAL4Mef2.PR cannot be suppressed by co-expression of Sod2Scer\UAS.cMa.
Expression of Sod2Scer\UAS.cMa suppresses the heart tube hypocontraction and increase in mitochondrial reactive oxygen species (ROS) seen when parkHMS01651 is expressed under the control of Scer\GAL4tin.CΔ4.
Expression of Sod2Scer\UAS.cMa suppresses the heart tube hypocontraction and increase in mitochondrial reactive oxygen species (ROS) seen when parkHMS01800 is expressed under the control of Scer\GAL4tin.CΔ4.
Co-expression of SodScer\UAS.cWa and Sod2Scer\UAS.cMa in cardiomyocytes and nonmyocytic pericardial cells, under the control of Scer\GAL4Hand.PA, which results in a significant increase in the level of physiological reactive oxygen species, has no significant effects on any major aspects of heart function, including heart rhythm or heart tube dimensions.
Expression of Sod2Scer\UAS.cMa strongly suppresses the hemocyte overproliferation seen in third instar larvae when Hsap\RUNX1::Hsap\RUNX1T1Scer\UAS.cSa is expressed under the control of Scer\GAL4Hml.Δ.