FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term presynaptic active zone ID (Ontology) GO:0048786 (Gene Ontology)
Definition A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.[ PubMed:3152289 ]
Also Known As"pre-synaptic active zone" ; "presynaptic specialization"
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Annotations
Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Genes (FBgn)GO_CELLULAR_COMPONENT
Insertions (FBti)EXPRESSION_STAGE_TISSUE_POSITION
Constructs (FBtp)PHENOTYPE_MANIFEST_IN
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 presynaptic active zone (all annotations which use CV term, excluding "NOT" statements)
     colocalizes_with | presynaptic active zone       --
      --       --
     is_active_in | presynaptic active zone       --
      --       --
     located_in | presynaptic active zone       --
      --       --
     presynaptic active zone | adult stage
      --       --
     presynaptic active zone | adult stage | decreased number
      --       --
     presynaptic active zone | cell autonomous | larval stage | somatic clone
      --       --       --
     presynaptic active zone | decreased number
      --       --       --
     presynaptic active zone | decreased number | larval stage
      --       --
     presynaptic active zone | decreased number | third instar larval stage
      --       --
     presynaptic active zone | ectopic | pharate adult stage
      --       --
     presynaptic active zone | increased number
      --       --
     presynaptic active zone | increased number | larval stage
      --       --
     presynaptic active zone | increased number | pupal stage
      --       --       --
     presynaptic active zone | increased number | third instar larval stage
      --       --
     presynaptic active zone | larval stage
      --       --
     presynaptic active zone | somatic clone
      --       --       --
     presynaptic active zone | third instar larval stage
      --       --
Spanning Tree (Parents/Children)
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Vocabulary search 
cellular_component
 |__cellular anatomical structure__
synapse                            |
 |__presynapse_____________________|
cellular anatomical structure      |
 |__presynapse_____________________|
                                   presynaptic active zone  107 rec.
                                    |__presynaptic active zone cytoplasmic component 14 rec.
                                    |   |__cytoskeleton of presynaptic active zone(+) 13 rec.
                                    |__presynaptic active zone dense projection
                                    |__presynaptic active zone membrane 6 rec.
                                    |   |__extrinsic component of presynaptic active zone membrane
                                    |__presynaptic grid
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Is a cellular anatomical structure
Part of presynapse
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Synonyms
  • "pre-synaptic active zone" EXACT
    "pre-synaptic active zone component" NARROW
    "presynaptic specialization" EXACT
Secondary IDs
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NIF_Subcellular:sao792027222