p38bΔ45 homozygous mutants do not display defects in locomotor behaviour.
Young p38bΔ45 mutants do not display defects in circadian behaviour.
Aged p38bΔ45 mutants display increased arrhythmicity and a modest but significant increase in tau of 24.9h compared with controls.
Mutant larvae show an increase in maximum bouton diameter at the neuromuscular junction compared to controls. Mutant larvae show a mild defect in axonal transport.
The ability of injured axons to sprout after injury is normal in mutant larvae.
Homozygous p38bΔ45 mutants have significantly reduced lifespans compared to controls, although no change in lifespan is seen in heterozygotes. 3 day old p38bΔ45 females occasionally exhibit aberrant walking behaviour and 1-2 day old flies are significantly more sensitive to heat shock and hydrogen peroxide-induced oxidative stress compared to controls.