FlyBase Allele Report: Scer\GAL4[Fer2.2359]

General Information

Symbol

Scer\GAL4^Fer2.2359

Species

S. cerevisiae

Name

FlyBase ID

FBal0299747

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{Fer2-GAL4.2359}

Also Known As

Fer2-GAL4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Bou Dib et al., 2014)

Progenitor genotype

Carried in construct

P{Fer2-GAL4.2359}

Cytology

Description

2359bp of Fer2 sequences from directly upstream of the translation initiation codon are fused upstream of a GAL4 driver.

(Bou Dib et al., 2014)

Allele components

Component

Use(s)

Regulatory region(s)

Fer2

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal neuroanatomy, with Fer2^RNAi.UAS.5

(Bou Dib et al., 2014)

abnormal neuroanatomy | adult stage, with B4^UAS.cSa

(Miozzo et al., 2022)

abnormal neuroanatomy | adult stage, with CG4998^GL00497

(Miozzo et al., 2022)

abnormal neuroanatomy | adult stage, with ftz-f1^α.UAS.cBa

(Miozzo et al., 2022)

abnormal neuroanatomy | adult stage, with Gucy2d^GS9223

(Miozzo et al., 2022)

abnormal neuroanatomy | adult stage, with osa^UAS.cCa

(Miozzo et al., 2022)

abnormal neuroanatomy | adult stage, with Snoo^s-236

(Miozzo et al., 2022)

abnormal neuroanatomy | adult stage | progressive, with Lrrk^I1915T.UAS

(Miozzo et al., 2022)

abnormal neuroanatomy | adult stage | progressive, with Lrrk^UAS.cIa

(Miozzo et al., 2022)

decreased cell number | adult stage, with B4^UAS.cSa

(Miozzo et al., 2022)

decreased cell number | adult stage, with CG4998^GL00497

(Miozzo et al., 2022)

decreased cell number | adult stage, with foxo^GD4348

(Tas et al., 2018)

decreased cell number | adult stage, with ftz-f1^α.UAS.cBa

(Miozzo et al., 2022)

decreased cell number | adult stage, with Gucy2d^GS9223

(Miozzo et al., 2022)

decreased cell number | adult stage, with osa^UAS.cCa

(Miozzo et al., 2022)

decreased cell number | adult stage, with Snoo^s-236

(Miozzo et al., 2022)

decreased cell number | adult stage | progressive, with Lrrk^I1915T.UAS

(Miozzo et al., 2022)

decreased cell number | adult stage | progressive, with Lrrk^UAS.cIa

(Miozzo et al., 2022)

Phenotype Manifest In

adult dopaminergic PAM neuron, with Fer2^RNAi.UAS.5

(Bou Dib et al., 2014)

adult dopaminergic PAM neuron | adult stage, with foxo^GD4348

(Tas et al., 2018)

adult dopaminergic PAM neuron | adult stage | decreased number, with B4^UAS.cSa

(Miozzo et al., 2022)

adult dopaminergic PAM neuron | adult stage | decreased number, with CG4998^GL00497

(Miozzo et al., 2022)

adult dopaminergic PAM neuron | adult stage | decreased number, with ftz-f1^α.UAS.cBa

(Miozzo et al., 2022)

adult dopaminergic PAM neuron | adult stage | decreased number, with Gucy2d^GS9223

(Miozzo et al., 2022)

adult dopaminergic PAM neuron | adult stage | decreased number, with Lrrk^I1915T.UAS

(Miozzo et al., 2022)

adult dopaminergic PAM neuron | adult stage | decreased number, with Lrrk^UAS.cIa

(Miozzo et al., 2022)

adult dopaminergic PAM neuron | adult stage | decreased number, with osa^UAS.cCa

(Miozzo et al., 2022)

adult dopaminergic PAM neuron | adult stage | decreased number, with Snoo^s-236

(Miozzo et al., 2022)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Lrrk^I1915T.UAS, Scer\GAL4^Fer2.2359 has decreased cell number | adult stage | progressive phenotype, enhanceable by Fer2^MB09480/Fer2^MB09480

(Miozzo et al., 2022)

Lrrk^I1915T.UAS, Scer\GAL4^Fer2.2359 has abnormal neuroanatomy | adult stage | progressive phenotype, enhanceable by Fer2^MB09480/Fer2^MB09480

(Miozzo et al., 2022)

Lrrk^UAS.cIa, Scer\GAL4^Fer2.2359 has abnormal neuroanatomy | adult stage | progressive phenotype, enhanceable by Fer2^MB09480/Fer2^MB09480

(Miozzo et al., 2022)

Lrrk^UAS.cIa, Scer\GAL4^Fer2.2359 has decreased cell number | adult stage | progressive phenotype, enhanceable by Fer2^MB09480/Fer2^MB09480

(Miozzo et al., 2022)

Enhancer of

Statement

Reference

Lrrk^UAS.cIa/Scer\GAL4^Fer2.2359 is an enhancer of abnormal neuroanatomy | adult stage | progressive phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Lrrk^UAS.cIa/Scer\GAL4^Fer2.2359 is an enhancer of decreased cell number | adult stage | progressive phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Scer\GAL4^Fer2.2359/Lrrk^I1915T.UAS is an enhancer of abnormal neuroanatomy | adult stage | progressive phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Scer\GAL4^Fer2.2359/Lrrk^I1915T.UAS is an enhancer of decreased cell number | adult stage | progressive phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Fer2^RNAi.UAS.5/Scer\GAL4^Fer2.2359 is an enhancer of decreased cell number | adult stage | recessive | progressive phenotype of foxo^Δ94

(Tas et al., 2018)

Suppressor of

Statement

Reference

Sod2^UAS.cMa/Scer\GAL4^Fer2.2359 is a suppressor | partially of abnormal neuroanatomy | adult stage | progressive phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Sod2^UAS.cMa/Scer\GAL4^Fer2.2359 is a suppressor | partially of decreased cell number | adult stage | progressive phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Fer2^UAS.Tag:FLAG/Scer\GAL4^Fer2.2359 is a suppressor of decreased cell number | recessive | adult stage | progressive phenotype of foxo^Δ94

(Tas et al., 2018)

Scer\GAL4^Fer2.2359/Cele\hlh-13^UAS.cDa is a suppressor | partially of abnormal neuroanatomy phenotype of Fer2^e03248

(Bou Dib et al., 2014)

Phenotype Manifest In

Enhanced by

Statement

Reference

Lrrk^I1915T.UAS, Scer\GAL4^Fer2.2359 has adult dopaminergic PAM neuron | adult stage | decreased number phenotype, enhanceable by Fer2^MB09480/Fer2^MB09480

(Miozzo et al., 2022)

Lrrk^UAS.cIa, Scer\GAL4^Fer2.2359 has adult dopaminergic PAM neuron | adult stage | decreased number phenotype, enhanceable by Fer2^MB09480/Fer2^MB09480

(Miozzo et al., 2022)

Enhancer of

Statement

Reference

Scer\GAL4^Fer2.2359/Lrrk^I1915T.UAS is an enhancer of adult dopaminergic PAM neuron | adult stage | decreased number phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Lrrk^UAS.cIa/Scer\GAL4^Fer2.2359 is an enhancer of adult dopaminergic PAM neuron | adult stage | decreased number phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Fer2^RNAi.UAS.5/Scer\GAL4^Fer2.2359 is an enhancer of adult dopaminergic PAM neuron | adult stage | progressive phenotype of foxo^Δ94

(Tas et al., 2018)

Suppressor of

Statement

Reference

Sod2^UAS.cMa/Scer\GAL4^Fer2.2359 is a suppressor | partially of adult dopaminergic PAM neuron | adult stage | decreased number phenotype of Fer2^MB09480

(Miozzo et al., 2022)

Fer2^UAS.Tag:FLAG/Scer\GAL4^Fer2.2359 is a suppressor of adult dopaminergic PAM neuron | adult stage | progressive phenotype of foxo^Δ94

(Tas et al., 2018)

Scer\GAL4^Fer2.2359/Cele\hlh-13^UAS.cDa is a suppressor | partially of adult dopaminergic PAM neuron phenotype of Fer2^e03248

(Bou Dib et al., 2014)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Fer2^UAS.Tag:FLAG/Scer\GAL4^Fer2.2359 rescues Fer2^MB09480

(Bou Dib et al., 2014)

Partially rescues

Fer2^UAS.Tag:FLAG/Scer\GAL4^Fer2.2359 partially rescues Fer2^e03248

(Bou Dib et al., 2014)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^Fer2.2359

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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