GAL4, G4, Gal
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Scer\GAL4 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Scer\GAL4 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Scer\GAL4 driving the expression of the toxin ricin A is a simple and efficient method of targetted cell ablation. Scer\GAL4 mediated ablation has been used to kill the interface glia that prefigure and then overlie the longitudinal axon tracts of the embryonic nerve cord. Ablation of these cells laeds to the misrouting, thinning or elimination of the longitudinal axon tracts, the glial cells are required for the formation of the longitudinal connectives.
A method that uses Cbβ\DT-A, the Scer\FLP1 recognition target sequences and the Scer\GAL4-Scer\UAS activation system can be used to ablate specific neurons in the embryo and to examine the consequences.