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Reference
Citation
Grieder, N.C., Charlafti, I., Kloter, U., Jäckle, H., Schäfer, U., Gehring, W.J. (2007). Misexpression screen in Drosophila melanogaster aiming to reveal novel factors involved in formation of body parts.  Genetics 175(4): 1707--1718.
FlyBase ID
FBrf0200458
Publication Type
Research paper
Abstract

To identify novel factors that lead a fly imaginal disc to adopt its developmental fate, we carried out a modular dominant misexpression screen in imaginal discs. We have identified two factors that appear to change the fate of the respective body structure and appear to lead to the transformation of a body part. In one mutant line, notum tissue, normally derived from wing imaginal tissue, formed close to the site of the sternopleural bristles, which are leg disc derivatives. In the other line, the arista is transformed into a tubular structure, resembling an abnormal leg. We found that ectopic expression of abrupt was responsible for this potential transformation of the arista.

PubMed ID
PubMed Central ID
PMC1855120 (PMC) (EuropePMC)
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Secondary IDs
  • FBrf0193839
Language of Publication
English
Additional Languages of Abstract
Parent Publication
Publication Type
Journal
Abbreviation
Genetics
Title
Genetics
Publication Year
1916-
ISBN/ISSN
0016-6731
Data From Reference
Alleles (101)
Genes (107)
Natural transposons (1)
Insertions (94)
Experimental Tools (1)
Transgenic Constructs (9)