FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Gene: Dmel\ab
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General Information
Symbol
Dmel\ab
Species
D. melanogaster
Name
abrupt
Annotation Symbol
CG43860
Feature Type
FlyBase ID
FBgn0264442
Gene Model Status
Stock Availability
Gene Summary
abrupt (ab) encodes a transcription factor that negatively regulates ecdysone signaling, as it binds to the product of tai. It regulates animal survival, organogenesis and multiple tissue morphogenesis, epithelial cell fate, cellular sexual identity, neuron differentiation and neuronal identity switch, cell migration, oncogenesis and germline differentiation. In many cell types, the product of ab is post-transcriptionally repressed by the steroid-induced miRNA let-7. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
Also Known As

clueless, clu

Key Links
Genomic Location
Cytogenetic map
Sequence location
Recombination map
2-44
RefSeq locus
NT_033779 REGION:11210678..11261080
Sequence
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
Function
Gene Ontology (GO) Annotations (11 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
non-traceable author statement
Biological Process (9 terms)
Terms Based on Experimental Evidence (6 terms)
CV Term
Evidence
References
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
traceable author statement
non-traceable author statement
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in nucleus
inferred from biological aspect of ancestor with PANTHER:PTN001135010
located_in nucleus
non-traceable author statement
Protein Family (UniProt)
-
Summaries
Gene Snapshot
abrupt (ab) encodes a transcription factor that negatively regulates ecdysone signaling, as it binds to the product of tai. It regulates animal survival, organogenesis and multiple tissue morphogenesis, epithelial cell fate, cellular sexual identity, neuron differentiation and neuronal identity switch, cell migration, oncogenesis and germline differentiation. In many cell types, the product of ab is post-transcriptionally repressed by the steroid-induced miRNA let-7. [Date last reviewed: 2019-03-07]
Gene Group (FlyBase)
C2H2 ZINC FINGER TRANSCRIPTION FACTORS -
Zinc finger C2H2 transcription factors are sequence-specific DNA binding proteins that regulate transcription. They possess DNA-binding domains that are formed from repeated Cys2His2 zinc finger motifs. (Adapted from PMID:1835093, FBrf0220103 and FBrf0155739).
Protein Function (UniProtKB)
Expression is vital for development; may be involved in transcriptional regulation. In embryos, muscle specific expression is required for segmental nerve b (SNb) motoneuron target recognition within ventral longitudinal muscles. Has a role in establishing and maintaining embryonic muscle attachments, adult sensory cell formation (macrochaetae) and morphogenesis of adult appendages (legs, antenna aristae and male external genitalia). Has a role in the morphogenesis of the class I dendritic neurons: selective expression of ab in class I da neurons plays a pivotal role in forming dendritic arbors, which are characteristic of the class I cells. The development of more complex arbors of class II-IV neurons depends on the absence of ab.
(UniProt, Q24174)
Phenotypic Description (Red Book; Lindsley and Zimm 1992)
ab: abrupt
thumb
ab: abrupt
Edith M. Wallace, unpublished.
Vein L5 usually stops after posterior crossvein. Scutellar bristles usually fewer. Wing effect probably acts during contraction period (Waddington). Overlaps wild type. Expression more severe in females than in males and when pupal stage takes place at 20 than at 25. TSP during the first 10% of pupal stage. (Thompson, Bruni, Carbonaro, and Russo, 1988, DIS 67: 86). RK2.
ab2
Vein L5 does not reach margin. Scutellar bristles always fewer than wild type. Hairs parted down midline of thorax and abdomen. Supra-alar bristles sometimes absent. Coxae tend to be thickened. Males sterile and have rotated genitalia. ab/ab2 resembles ab/ab but has a stronger bristle effect. RK2.
Summary (Interactive Fly)

transcription factor - zinc finger BTB domain - controls the specificity of neuromuscular connections - negative regulator of ecdysone signaling - post-transcriptionally repressed by the steroid-induced miRNA let-7

Gene Model and Products
Number of Transcripts
5
Number of Unique Polypeptides
3

Please see the JBrowse view of Dmel\ab for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q24174)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
Comments on Gene Model

Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters.

Gene model reviewed during 5.48

Gene model reviewed during 5.45

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
FBtr0332558
5164
904
FBtr0332557
4840
894
FBtr0332560
4888
894
FBtr0332561
4269
899
FBtr0332562
4490
894
Additional Transcript Data and Comments
Reported size (kB)

5.1 (northern blot)

Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
FBpp0304816
95.1
904
6.28
FBpp0304815
94.0
894
6.17
FBpp0304818
94.0
894
6.17
FBpp0304819
97.3
899
7.23
FBpp0304820
94.0
894
6.17
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

894 aa isoforms: ab-PB, ab-PD, ab-PF
Additional Polypeptide Data and Comments
Reported size (kDa)

904, 894 (aa)

Comments
External Data
Crossreferences
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\ab using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.91

Transcript Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data

ab is expressed in all the cells of the ventral midline starting in stage 9. The only other site of nervous system expression is the stomatogastric nervous system and its precursors. Epidermal expression begins in stage 11 in a pattern of stripes and is uniform by stage 12. ab is expressed in all 30 embryonic abdominal muscles with the highest concentrations in the ventral longitudinal, ventral oblique, and segmental border muscles. ab is also expressed in all imaginal discs.

Marker for
Subcellular Localization
CV Term
Polypeptide Expression
No Assay Recorded
Stage
Tissue/Position (including subcellular localization)
Reference
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Descriptive Data

ab is widely expressed in somatic and germline cells during oogenesis. During stage S9, the accumulation of protein in the nucleus decreases specifically in border cells. The ab antibody also stains the apical surfaces of follicle cells, the oocyte cortex, and ring canals.

ab is expressed in all the cells of the ventral midline starting in stage 9. The only other site of nervous system expression is the stomatogastric nervous system and its precursors. Epidermal expression begins in stage 11 in a pattern of stripes and is uniform by stage 12. ab is expressed in all 30 embryonic abdominal muscles with the highest concentrations in the ventral longitudinal, ventral oblique, and segmental border muscles. ab is also expressed in all imaginal discs.

Marker for
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
Expression Deduced from Reporters
Reporter: P{A92}abBL97
Stage
Tissue/Position (including subcellular localization)
Reference
Reporter: P{lwB}ab94
Stage
Tissue/Position (including subcellular localization)
Reference
Stage
Tissue/Position (including subcellular localization)
Reference
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\ab in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Images
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 42 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 19 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of ab
Transgenic constructs containing regulatory region of ab
Aberrations (Deficiencies and Duplications) ( 7 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
Sterility
Allele
Other Phenotypes
Allele
Phenotype manifest in
Allele
autophagic vacuole & larval fat body | somatic clone | cell autonomous
leg (with ab1)
leg (with ab1D)
leg (with ab60M)
leg (with abG9)
lysosome & larval fat body | somatic clone | cell autonomous
macrochaeta & wing
macrochaeta & wing (with ab1)
macrochaeta & wing (with ab1D)
macrochaeta & wing (with ab60M)
macrochaeta & wing (with abG9)
microchaeta & abdomen
microchaeta & thorax
mitochondrion & larval fat body | somatic clone | cell autonomous
Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (44)
3 of 14
Yes
No
2 of 14
No
Yes
2 of 14
No
Yes
2 of 14
No
Yes
2 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1  
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
No
1  
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (25)
2 of 14
Yes
No
2 of 14
Yes
Yes
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
Yes
Mus musculus (laboratory mouse) (20)
2 of 14
Yes
Yes
2 of 14
Yes
Yes
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (27)
2 of 13
Yes
Yes
2 of 13
Yes
Yes
2 of 13
Yes
Yes
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
No
1 of 13
No
Yes
1 of 13
No
Yes
1 of 13
No
No
Danio rerio (Zebrafish) (35)
2 of 14
Yes
Yes
2 of 14
Yes
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
No
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
1 of 14
No
Yes
Caenorhabditis elegans (Nematode, roundworm) (6)
1 of 14
Yes
No
1 of 14
Yes
No
1 of 14
Yes
Yes
1 of 14
Yes
No
1 of 14
Yes
No
1 of 14
Yes
No
Anopheles gambiae (African malaria mosquito) (48)
6 of 12
Yes
Yes
Arabidopsis thaliana (thale-cress) (1)
1 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (0)
Schizosaccharomyces pombe (Fission yeast) (0)
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:ab. Refer to their site for version information.
Paralogs
Paralogs (via DIOPT v9.1)
Drosophila melanogaster (Fruit fly) (38)
7 of 13
7 of 13
7 of 13
7 of 13
6 of 13
6 of 13
6 of 13
6 of 13
6 of 13
6 of 13
6 of 13
6 of 13
6 of 13
6 of 13
6 of 13
5 of 13
5 of 13
5 of 13
5 of 13
5 of 13
4 of 13
4 of 13
3 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
1 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Allele
Disease
Evidence
References
Potential Models Based on Orthology ( 0 )
Human Ortholog
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 1 )
Allele
Disease
Interaction
References
Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
Homo sapiens (Human)
Gene name
Score
OMIM
OMIM Phenotype
DO term
Complementation?
Transgene?
Functional Complementation Data
Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
Interactions
Summary of Physical Interactions
Summary of Genetic Interactions
Interaction Browsers

Please look at the allele data for full details of the genetic interactions
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
Starting gene(s)
Interaction type
Interacting gene(s)
Reference
External Data
Linkouts
DroID - A comprehensive database of gene and protein interactions.
MIST (genetic) - An integrated Molecular Interaction Database
MIST (protein-protein) - An integrated Molecular Interaction Database
Pathways
Signaling Pathways (FlyBase)
Metabolic Pathways
FlyBase
External Links
External Data
Linkouts
Class of Gene
Genomic Location and Detailed Mapping Data
Chromosome (arm)
2L
Recombination map
2-44
Cytogenetic map
Sequence location
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
32E1-32E2
Limits computationally determined from genome sequence between P{PZ}l(2)0400804008&P{PZ}cmet04431 and P{PZ}salm03602
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
32E1-32E2
Limits computationally determined from genome sequence between P{PZ}l(2)0400804008&P{PZ}cmet04431 and P{PZ}salm03602
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Stocks and Reagents
Stocks (49)
Genomic Clones (37)
cDNA Clones (82)
 

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced
BDGP DGC clones
Other clones
    Drosophila Genomics Resource Center cDNA clones

    For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

    cDNA Clones, End Sequenced (ESTs)
    BDGP DGC clones
    RNAi and Array Information
    Linkouts
    Antibody Information
    Laboratory Generated Antibodies
     

    polyclonal

    Commercially Available Antibodies
     
    Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
    Cell Line Information
    Publicly Available Cell Lines
     
      Other Stable Cell Lines
       
        Other Comments

        ab is a repressor of ecdysone signalling and border follicle cell migration.

        dsRNA has been made from templates generated with primers directed against this gene. ab RNAi causes an increase in dendrite arborization of ddaD and ddaE neurons. There is an increase in the number and length of lateral branches, which results in an expansion of the coverage field, most noticeably along the anteroposterior (AP) axis. In addition to these defects,ab RNAi also causes frequent cell death, defects in muscle, alterations in the number of MD neurons, defects in dendrite morphogenesis and reproducible defects in da dendrite development.

        New annotation (CG32830) in release 3 of the genome annotation.

        P-element excision and γ ray induced lethal mutations of the enhancer trap BL97 fail to complement ab.

        ab encodes a BTB-zinc finger regulatory protein that controls the specificity of neuromuscular connections.

        Loss of vein mutations cause suppression of rhohs.PSt ectopic vein phenotype and enhancement of the rhove-1 loss of vein phenotype.

        Identification: Mutations affecting neuromuscular connectivity, using an antibody to Fas2.

        Mutations in ab affect individual longitudinal veins: vein specific effects.

        kni, tg, tt, ab, cv, cv-2, cv-c and cv-d belong to the radius incompletus phenotypic group within the 'lack-of-vein' mutant class. Loss-of-function alleles at these loci remove stretches of veins in two or more longitudinal veins. Double mutants of this group have additive phenotypes suggesting the genes are vein-specific, and small lanceolate wings. Therefore involved in whole vein-region specification rather than vein differentiation. ab alleles may have pleiotropic effects on leg development or be embryonic lethal.

        Loss of function is lethal, with effects on connectivity of segmental nerves; hypomorphic alleles affect the development of wing veins, especially wing vein L5, with effects in coxa, male genitalia and bristles.

        Relationship to Other Genes
        Source for database merge of

        Source for merge of: ab B2149

        Source for merge of: ab CG32830

        Additional comments

        Annotations CG4807 and CG32830 merged as CG43860 in release 5.45 of the genome annotation. Merge supported by second tier modENCODE RNA-seq junction (FBrf0217580).

        Nomenclature History
        Source for database identify of

        Source for identity of: ab CG4807

        Nomenclature comments
        Etymology
        Synonyms and Secondary IDs (13)
        Reported As
        Symbol Synonym
        B2149
        CG32830
        ab
        (Jang et al., 2024, Kwon et al., 2024, Zhang et al., 2024, Floc'hlay et al., 2023, Titlow et al., 2023, Deshpande et al., 2022, National Institute of Genetics Fly Stocks, 2022-, DeAngelis et al., 2021, Ing-Simmons et al., 2021, Ma et al., 2021, Winbush and Singh, 2021, Xie et al., 2021, Chougule et al., 2020, Yoong et al., 2020, Shih et al., 2019, Shokri et al., 2019, Simoes da Silva et al., 2019, Bischof et al., 2018, Croset et al., 2018, Kittelmann et al., 2018, Aw et al., 2017, Karaiskos et al., 2017, Simoes da Silva et al., 2017, Transgenic RNAi Project members, 2017-, Preger-Ben Noon et al., 2016, Ravisankar et al., 2016, Diao et al., 2015, Nadimpalli et al., 2015, Sanhueza et al., 2015, Schertel et al., 2015, Yalgin et al., 2015, Bagley et al., 2014, Curtis et al., 2013, Djiane et al., 2013, Sen et al., 2013, FlyBase Genome Annotators, 2012, Japanese National Institute of Genetics, 2012.5.21, Kucherenko et al., 2012, Spokony and White, 2012.5.22, Tan et al., 2012, König et al., 2011, Pilgram et al., 2011, Cunha et al., 2010, Arsham and Neufeld, 2009, Long et al., 2009, Caygill and Johnston, 2008, Caygill and Johnston, 2008, Christensen and Cook, 2008.4.15, Cook et al., 2008, Franciscovich et al., 2008, Christensen and Cook, 2007.10.29, Grieder et al., 2007, Hattori et al., 2007, Komiyama and Luo, 2007, Minidorff et al., 2007, Quinones-Coello, 2007, Spokony and Restifo, 2007, Zeitlinger et al., 2007, Christensen and Cook, 2006.12.5, Cook, 2006.6.12, Crews and Brenman, 2006, Dorner et al., 2006, Kim et al., 2006, Molnar et al., 2006, Zhang et al., 2006, Burgler and Macdonald, 2005, Stark et al., 2005, Brodsky et al., 2004, Li et al., 2004, Sugimura et al., 2004)
        l(2)k02807
        ptd
        Secondary FlyBase IDs
        • FBgn0259750
        • FBgn0259599
        • FBgn0000011
        • FBgn0013436
        • FBgn0022233
        • FBgn0052830
        Datasets (0)
        Study focus (0)
        Experimental Role
        Project
        Project Type
        Title
        Study result (0)
        Result
        Result Type
        Title
        External Crossreferences and Linkouts ( 66 )
        Sequence Crossreferences
        NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
        GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
        RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
        UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
        UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information
        UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
        Other crossreferences
        AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
        BDGP expression data - Patterns of gene expression in Drosophila embryogenesis
        DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
        EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
        FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
        KEGG Genes - Molecular building blocks of life in the genomic space.
        MARRVEL_MODEL - MARRVEL (model organism gene)
        Linkouts
        Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
        DroID - A comprehensive database of gene and protein interactions.
        Developmental Studies Hybridoma Bank - Monoclonal antibodies for use in research
        Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
        FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
        FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
        Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
        iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
        Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution
        MIST (genetic) - An integrated Molecular Interaction Database
        MIST (protein-protein) - An integrated Molecular Interaction Database
        References (205)