FlyBase Allele Report: Scer\GAL4[21-7]

General Information

Symbol

Scer\GAL4^21-7

Species

S. cerevisiae

Name

FlyBase ID

FBal0246937

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

P{GAL4}21-7

Carried in Construct

Also Known As

21-7-GAL4, Gal4^21-7, MD-Gal4, GAL4²¹⁷, 21-7

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Associated Insertion(s)

P{GAL4}21-7

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{GAL4}

enhancer trap

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

multidendritic neuron

(Cheng et al., 2010)

third instar larval stage

larval dorsal multidendritic neuron ddaE

(Hattori et al., 2013)

larval dorsal multidendritic neuron ddaC

(Hattori et al., 2013)

Additional Information

Statement

Reference

Drives expression in multidendritic neurons.

(FlyBase Curators, 2017)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal heat stress response, with TrpA1^GD2375

(Neely et al., 2011)

abnormal locomotor behavior | third instar larval stage | heat sensitive, with shi^1.UAS

(Song et al., 2007)

abnormal neuroanatomy, with ab^{UAS.Tag:Dam,Tag:MYC}

(Hattori et al., 2013)

abnormal neuroanatomy, with AGO1^HMC03509

(Lee et al., 2015)

abnormal neuroanatomy, with kn^{UAS.Tag:Dam,Tag:MYC}

(Hattori et al., 2013)

abnormal neuroanatomy, with mys^GD15002

(Han et al., 2012)

abnormal neuroanatomy, with Ret^JF01968

(Soba et al., 2015)

abnormal neuroanatomy, with Ret^KK107206

(Soba et al., 2015)

abnormal neuroanatomy, with trc^KK109419

(Lee et al., 2015)

abnormal neuroanatomy | somatic clone, with kn^UAS.cMa

(Ye et al., 2011)

abnormal neuroanatomy | third instar larval stage, with PlexB^GD3150

(Meltzer et al., 2016)

abnormal neuroanatomy | third instar larval stage, with PlexB^GD14473

(Meltzer et al., 2016)

abnormal neuroanatomy | third instar larval stage, with Ret^{TKΔ.UAS.Tag:V5}

(Hoyer et al., 2018)

abnormal neuroanatomy | third instar larval stage, with Ret^UAS.Tag:V5

(Hoyer et al., 2018)

abnormal sensory perception, with Piezo^NIG.8486R

(Gou et al., 2014)

abnormal stress response | larval stage, with axed^HMJ22228

(Ji et al., 2022)

abnormal thermotaxis, with TrpA1^GD2375

(Neely et al., 2011)

paralytic | third instar larval stage | heat sensitive, with shi^1.UAS

(Song et al., 2007)

Phenotype Manifest In

axon | larval stage, with axed^HMJ22228

(Ji et al., 2022)

dendrite, with AGO1^HMC03509

(Lee et al., 2015)

dendrite, with trc^KK109419

(Lee et al., 2015)

dendrite | third instar larval stage, with PlexB^GD3150

(Meltzer et al., 2016)

dendrite | third instar larval stage, with PlexB^GD14473

(Meltzer et al., 2016)

dendritic arborizing neuron | somatic clone, with kn^UAS.cMa

(Ye et al., 2011)

dendritic arborizing neuron | third instar larval stage, with ab^{UAS.Tag:Dam,Tag:MYC}

(Hattori et al., 2013)

dendritic arborizing neuron | third instar larval stage, with kn^{UAS.Tag:Dam,Tag:MYC}

(Hattori et al., 2013)

dendritic tree | third instar larval stage, with ab^{UAS.Tag:Dam,Tag:MYC}

(Hattori et al., 2013)

dendritic tree | third instar larval stage, with kn^{UAS.Tag:Dam,Tag:MYC}

(Hattori et al., 2013)

dendritic tree | third instar larval stage, with Ret^{TKΔ.UAS.Tag:V5}

(Hoyer et al., 2018)

dendritic tree | third instar larval stage, with Ret^UAS.Tag:V5

(Hoyer et al., 2018)

larval dorsal multidendritic neuron ddaC, with axed^HMJ22228

(Ji et al., 2022)

larval dorsal multidendritic neuron ddaC, with mys^GD15002

(Han et al., 2012)

larval multidendritic class IV neuron, with AGO1^HMC03509

(Lee et al., 2015)

larval multidendritic class IV neuron, with Ret^JF01968

(Soba et al., 2015)

larval multidendritic class IV neuron, with Ret^KK107206

(Soba et al., 2015)

larval multidendritic class IV neuron, with trc^KK109419

(Lee et al., 2015)

larval multidendritic class IV neuron | third instar larval stage, with PlexB^GD3150

(Meltzer et al., 2016)

larval multidendritic class IV neuron | third instar larval stage, with PlexB^GD14473

(Meltzer et al., 2016)

larval multidendritic class IV neuron | third instar larval stage, with Ret^{TKΔ.UAS.Tag:V5}

(Hoyer et al., 2018)

larval multidendritic class IV neuron | third instar larval stage, with Ret^UAS.Tag:V5

(Hoyer et al., 2018)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

AGO1^HMC03509, Scer\GAL4^21-7 has abnormal neuroanatomy phenotype, non-enhanceable by trc^KK109419, Scer\GAL4^21-7

(Lee et al., 2015)

Scer\GAL4^21-7, trc^KK109419 has abnormal neuroanatomy phenotype, non-enhanceable by AGO1^HMC03509, Scer\GAL4^21-7

(Lee et al., 2015)

Suppressed by

Statement

Reference

Scer\GAL4^21-7, kn^UAS.cMa has abnormal neuroanatomy | somatic clone phenotype, suppressible by dar1³⁰¹⁰

(Ye et al., 2011)

NOT Enhancer of

Statement

Reference

Scer\GAL4^21-7/ATP8A^UAS.Tag:FLAG is a non-enhancer of decreased size | larval stage phenotype of Nmnat^U6:3.gRNA, Spyo\Cas9^ppk.PP

(Ji et al., 2022)

trc^KK109419, Scer\GAL4^21-7 is a non-enhancer of abnormal neuroanatomy phenotype of AGO1^HMC03509, Scer\GAL4^21-7

(Lee et al., 2015)

AGO1^HMC03509, Scer\GAL4^21-7 is a non-enhancer of abnormal neuroanatomy phenotype of Scer\GAL4^21-7, trc^KK109419

(Lee et al., 2015)

Suppressor of

Statement

Reference

Scer\GAL4^21-7/ATP8A^UAS.Tag:FLAG is a suppressor | partially of abnormal neuroanatomy | larval stage phenotype of Nmnat^U6:3.gRNA, Spyo\Cas9^ppk.PP

(Ji et al., 2022)

NOT Suppressor of

Statement

Reference

Scer\GAL4^21-7/ATP8A^UAS.Tag:FLAG is a non-suppressor of decreased size | larval stage phenotype of Nmnat^U6:3.gRNA, Spyo\Cas9^ppk.PP

(Ji et al., 2022)

kn^UAS.cMa/Scer\GAL4^21-7 is a non-suppressor of abnormal neuroanatomy phenotype of dar1³⁰¹⁰

(Ye et al., 2011)

Phenotype Manifest In

NOT Enhanced by

Statement

Reference

Scer\GAL4^21-7, trc^KK109419 has larval multidendritic class IV neuron phenotype, non-enhanceable by AGO1^HMC03509, Scer\GAL4^21-7

(Lee et al., 2015)

Scer\GAL4^21-7, trc^KK109419 has dendrite phenotype, non-enhanceable by AGO1^HMC03509, Scer\GAL4^21-7

(Lee et al., 2015)

AGO1^HMC03509, Scer\GAL4^21-7 has larval multidendritic class IV neuron phenotype, non-enhanceable by trc^KK109419, Scer\GAL4^21-7

(Lee et al., 2015)

AGO1^HMC03509, Scer\GAL4^21-7 has dendrite phenotype, non-enhanceable by trc^KK109419, Scer\GAL4^21-7

(Lee et al., 2015)

Suppressed by

Statement

Reference

Scer\GAL4^21-7, kn^UAS.cMa has dendritic arborizing neuron | somatic clone phenotype, suppressible by dar1³⁰¹⁰

(Ye et al., 2011)

NOT Enhancer of

Statement

Reference

AGO1^HMC03509, Scer\GAL4^21-7 is a non-enhancer of larval multidendritic class IV neuron phenotype of Scer\GAL4^21-7, trc^KK109419

(Lee et al., 2015)

AGO1^HMC03509, Scer\GAL4^21-7 is a non-enhancer of dendrite phenotype of Scer\GAL4^21-7, trc^KK109419

(Lee et al., 2015)

trc^KK109419, Scer\GAL4^21-7 is a non-enhancer of larval multidendritic class IV neuron phenotype of AGO1^HMC03509, Scer\GAL4^21-7

(Lee et al., 2015)

trc^KK109419, Scer\GAL4^21-7 is a non-enhancer of dendrite phenotype of AGO1^HMC03509, Scer\GAL4^21-7

(Lee et al., 2015)

Suppressor of

Statement

Reference

Scer\GAL4^21-7/ATP8A^UAS.Tag:FLAG is a suppressor | partially of dendrite | larval stage phenotype of Nmnat^U6:3.gRNA, Spyo\Cas9^ppk.PP

(Ji et al., 2022)

Scer\GAL4^21-7/ATP8A^UAS.Tag:FLAG is a suppressor | partially of larval dorsal multidendritic neuron ddaC phenotype of Nmnat^U6:3.gRNA, Spyo\Cas9^ppk.PP

(Ji et al., 2022)

NOT Suppressor of

Statement

Reference

kn^UAS.cMa/Scer\GAL4^21-7 is a non-suppressor of dendritic arborizing neuron phenotype of dar1³⁰¹⁰

(Ye et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescues

Scer\GAL4^21-7/path^A.UAS.GFP rescues path^dg50/Df(3L)BSC773

(Lin et al., 2015)

Scer\GAL4^21-7/Nmnat^WR.UAS.PD rescues Nmnat^Δ4790-2

(Wen et al., 2011)

Scer\GAL4^21-7/nompC^L.UAS rescues nompC¹/nompC³

(Cheng et al., 2010)

Comments

Images (0)

Mutant

Wild-type

Stocks (2)

Bloomington

603618

w¹¹¹⁸; P{GAL4}21-7/SM6a

81892

w^*; P{GAL4}21-7, P{UAS-CD4-tdGFP}8M2/CyO, P{Wee-P.ph0}2; P{UAS-RedStinger}6, PBac{U6-GFP.gRNA.ACDG}VK00027/TM6B, Tb¹

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

GAL4^21-7

(Bhattacharjee et al., 2023, Clark et al., 2018, Hattori et al., 2013)

GAL4²¹⁷

(Bhattacharjee et al., 2023, Bhattacharjee et al., 2022)

Gal4^21-7

(Xu et al., 2024, Ji et al., 2022, Meltzer et al., 2017, Meltzer et al., 2016, Iyer et al., 2013)

Scer\GAL4^21-7

Name Synonyms

Secondary FlyBase IDs

References (43)

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