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General Information
Symbol
Dmel\pathA.UAS.GFP
Species
D. melanogaster
Name
FlyBase ID
FBal0305311
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulates expression of the long 'A' (471 aa) isoform of path tagged with GFP.

Allele components
Product class / Tool use(s)
Encoded product / tool
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Overexpression of pathA.Scer\UAS.T:Avic\GFP in C1da neurons of otherwise wild-type larvae using Scer\GAL4221 promotes a modest but significant increase in C1da dendrite growth. In contrast, pathA.Scer\UAS.T:Avic\GFP overexpression using Scer\GAL4ppk.PG has no effect on the total dendrite length of C4da neurons.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference

Scer\GAL4ppk.PG-mediated co-expression of pathA.Scer\UAS.T:Avic\GFP and RhebScer\UAS.cPa promote dendritic growth, whereas expression of either alone has no such effect.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

Scer\GAL4Act5C.PI-mediated expression of pathA.Scer\UAS.T:Avic\GFP rescues the dendrite defects in pathdg50 mutants.

A heat-shock induced pulse of expression of pathA.Scer\UAS.T:Avic\GFP (using Scer\GAL4hs.PB) at 24, 48, 72 or 96 hours AEL is sufficient to significantly rescue dendrite growth defects of pathdg50/Df(3L)BSC773 animals.

pathA.Scer\UAS.T:Avic\GFP expression in pathdg50 MARCM clones rescues their C4da dendrite growth defects.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
pathA.Scer\UAS.T:Avic\GFP
pathA.UAS.GFP
Name Synonyms
Secondary FlyBase IDs
    References (1)