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| Term | binary expression system - driver | ID (Ontology) | FBcv:0005059 (FlyBase CV) | |||||||||||||||||
| Definition | Transactivator ('driver') that is encoded by a transgenic locus or modified endogenous locus and which forms part of a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.[ FlyBase:FBrf0216478 ] | |||||||||||||||||||
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experimental tool descriptor |__binary expression system component |__binary expression system - driver 57 rec. |__binary expression system - conditional driver 16 rec. |__binary expression system - light-regulated driver 3 rec. |__binary expression system - small molecule-regulated driver 13 rec. |
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| Is a | binary expression system component | ||
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