FB2026_03 , released September 17, 2026
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
mir-let7, ab
FlyBase ID
FBig0000104213
Interaction Network
Interactions Browser links
mir-let7 network
ab network
Reported Interactions
FBrf0187121-1.miR-mRNA.LUC
Reference
Burgler and Macdonald, 2005
Description
physical association
Assay
Collection
Source/Stage
Cell line used
S2-DGRC
Participants
Corresponds to
Reported as
Role
Note
mir-let7 

let-7

bait
ab 

ab

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

luciferase reporter assay

(Burgler and Macdonald, 2005)

Source was S2 cell line; bait produced from transfected construct; prey produced from transfected reporter construct.

(Burgler and Macdonald, 2005)
FBrf0220235-1.miR-mRNA.IHC
Reference
Kucherenko et al., 2012
Description
physical association
Assay
Collection
Source/Stage
embryonic/larval mushroom body / third instar larval stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
mir-let7 

let-7

bait
ab 

Abrupt

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Overexpression of let-7 reduces ab protein levels.

(Kucherenko et al., 2012)

Source was larval brain of transgenic fly line; bait produced from transgenic construct; prey produced from endogenous gene.

(Kucherenko et al., 2012)
External Crossreferences and Linkouts ( 0 )
References (2)