BTB/POZ domain transcription factor - helps specify distinct birth order-dependent cell fates in an extended neuronal lineage - regulates the time at which neuroblasts undergo Prospero-dependent cell-cycle exit or Reaper/Hid/Grim-dependent apoptosis
Please see the JBrowse view of Dmel\chinmo for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Stop-codon suppression supported by data in FBrf0216884.
Gene model reviewed during 5.41
Stop-codon suppression (UAG) postulated (FBrf0210979, FlyBase analysis); supported by conservation of the extended ORF across Drosophila species (FBrf0202906).
Gene model reviewed during 5.45
Tissue-specific extension of 3' UTRs observed during later stages (FBrf0218523, FBrf0219848); all variants may not be annotated
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\chinmo using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
Comment: maternally deposited
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as procephalic ectoderm primordium
Comment: reported as dorsal/lateral sensory complexes
chinmo protein is present in all of the cells of the wing disc epithelium (including the wing pouch and notum) in early third instar larval development and is down-regulated around mid L3. chinmo protein is still present at 20 hours after the L2/L3 molt but is completely absent after 30 hours. chinmo down-regulation correlates with br activation in the wing disc throughout L3. A particular isoform of br was identified as being expressed from 30 hours forward. chinmo silencing requires that larvae pass the critical weight, which normall occurs 8-12 hours after the Lw/L3 molt.
chinmo protein is localized to the nuclei of mushroom body neurons at mid-third larval instar.
JBrowse - Visual display of RNA-Seq signals
View Dmel\chinmo in JBrowse



2-3
2-2.9
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
chinmo is required autonomously to maintain the male identity of adult somatic cyst stem cells in the testis.
DNA-protein interactions: genome-wide binding profile assayed for chinmo protein in 0-12 hr embryos; see mE1_TFBS_chinmo collection report.
chinmo is required in only one of the six fates of the Scer\GAL4OK107-positive central complex neurons.
Loss of chinmo causes various types of early-born neurons to adopt distinct late-born mushroom body neurons' projection patterns but exerts no effects on pupal-born mushroom body neurons.
Source for merge of: chinmo l(2)04111 CG31666
Source for merge of: CG10871 CG17156
Source for merge of: CG10871 CG17649
Annotations CG10871, CG17156 and CG17649 merged as CG31666 in release 3 of the genome annotation.
Source for merge of CG10871 CG17156 was a shared cDNA ( date:010720 ).