FlyBase Allele Report: Dmel\chinmo[RNAi.UAS.cCa]

General Information

Symbol

Dmel\chinmo^RNAi.UAS.cCa

Species

D. melanogaster

Name

FlyBase ID

FBal0369020

Feature type

allele

Associated gene

Dmel\chinmo

Associated Insertion(s)

Carried in Construct

PBac{UAS-chinmo.RNAi.C}

Also Known As

P{w+, UAS-chinmo<up>RNAi 148</up>}

Key Links

Transgenic product class

RNAi_reagent

(Chawla et al., 2016)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Chawla et al., 2016)

Mutagen

in vitro construct

(Chawla et al., 2016)

Progenitor genotype

Carried in construct

PBac{UAS-chinmo.RNAi.C}

Cytology

Description

UAS regulatory sequences drive expression of a short hairpin RNA (TGTGGGCTTTG AATACTACGC) targeting chinmo.

(Chawla et al., 2016)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

chinmo

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

long lived | RU486 conditional, with Scer\GAL4^Switch1.106

(Pandey et al., 2021)

Phenotype Manifest In

adult fat body | RU486 conditional, with Scer\GAL4^Switch1.106

(Pandey et al., 2021)

lipid droplet | adult stage | RU486 conditional, with Scer\GAL4^Switch1.106

(Pandey et al., 2021)

Detailed Description

Statement

Reference

The expression of chinmo^{dsRNA.UAS.cCa} under the control of Scer\GAL4^Switch1.106 leads to extended lifespan and enlarged lipid droplets in the adult fat body, either under ad libitum diet or under dietary restrictions.

(Pandey et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

chinmo^RNAi.UAS.cCa/Scer\GAL4^let7C is a suppressor of abnormal neuroanatomy | adult stage | progressive phenotype of Df(2L)let-7-C^GKI/lncRNA:let7C^KO2, lncRNA:let7C^Δmir-125

(Chawla et al., 2016)

chinmo^RNAi.UAS.cCa/Scer\GAL4^let7C is a suppressor | partially of abnormal locomotor behavior | adult stage | progressive phenotype of Df(2L)let-7-C^GKI/lncRNA:let7C^KO2, lncRNA:let7C^Δmir-125

(Chawla et al., 2016)

Phenotype Manifest In

Suppressor of

Statement

Reference

chinmo^RNAi.UAS.cCa/Scer\GAL4^let7C is a suppressor | partially of lipid droplet | adult stage phenotype of mir-125^Δ.cSa

(Pandey et al., 2021)

chinmo^RNAi.UAS.cCa/Scer\GAL4^let7C is a suppressor | partially of adult fat body | adult stage phenotype of mir-125^Δ.cSa

(Pandey et al., 2021)

chinmo^RNAi.UAS.cCa/Scer\GAL4^let7C is a suppressor of adult brain phenotype of Df(2L)let-7-C^GKI/lncRNA:let7C^KO2, lncRNA:let7C^Δmir-125

(Chawla et al., 2016)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

chinmo^RNAi.UAS.cCa

chinmo^{dsRNA.UAS.cCa}

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

Open Close