FlyBase Allele Report: Scer\GAL4[A3.eya]

General Information

Symbol

Scer\GAL4^A3.eya

Species

S. cerevisiae

Name

FlyBase ID

FBal0266864

Feature type

allele

Associated gene

Scer\GAL4

Associated Insertion(s)

Carried in Construct

P{eya-GAL4.A3}

Also Known As

eyaA3-GAL4, eya-Gal4, EyaGal4

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Leatherman and DiNardo, 2008)

Progenitor genotype

Carried in construct

P{eya-GAL4.A3}

Cytology

Description

A 5.8 kb genomic fragment flanking the start of the eya-RA cDNA regulates expression of a GAL4 driver.

(Leatherman and DiNardo, 2008)

Allele components

Component

Use(s)

Regulatory region(s)

eya

Encoded product / tool

GAL4

binary expression system - driver

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage | male

cyst progenitor cell

(Leatherman and DiNardo, 2008)

male germline cyst

(Leatherman and DiNardo, 2008)

cyst cell of testis

(Rotkopf et al., 2011)

adult stage | male & spermatogenesis

spermatogonial cyst cell

(Fairchild et al., 2016)

cyst progenitor cell | faint

(Fairchild et al., 2016)

Additional Information

Statement

Reference

ScerGAL4^A3.eya drives strong expression in male somatic cyst cells; expression is stronger than that of ScerGAL4^PpY-55A.PJ.

(Rotkopf et al., 2011)

Drives low level expression in male germline cyst progenitor cells and high levels in cyst cells.

(Leatherman and DiNardo, 2008)

Marker for

Reflects expression of

eya

(Rotkopf et al., 2011)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell cycle | adult stage, with dsx^RNAi.UAS

(Ma et al., 2014)

decreased cell number | spermatogenesis, with Dp^GD4444

(Herrera et al., 2021)

increased cell number | adult stage, with dsx^RNAi.UAS

(Ma et al., 2014)

increased cell number | adult stage | male, with chinmo^UAS.fl

(Flaherty et al., 2010)

increased cell number | male, with E(z)^HMS00066

(Eun et al., 2014)

increased occurrence of cell division | adult stage, with chinmo^UAS.fl

(Flaherty et al., 2010)

lethal, with zfh1^UAS.cPa

(Leatherman and DiNardo, 2008)

male sterile, with Cdc42^NIG.12530R

(Rotkopf et al., 2011)

male sterile, with sns^GD65

(Rotkopf et al., 2011)

male sterile, with Vrp1^KK111261

(Rotkopf et al., 2011)

male sterile, with WASp^KK102768

(Rotkopf et al., 2011)

viable, with Scer\GAL80^ts.αTub84B, zfh1^UAS.cPa

(Leatherman and DiNardo, 2008)

viable, with Sumo^JF02869

(Rinehart et al., 2024)

Phenotype Manifest In

cyst cell of testis, with alien^HM05119

(Qian et al., 2015)

cyst cell of testis, with CSN1b^JF02612

(Qian et al., 2015)

cyst cell of testis | adult stage | ectopic | increased number, with chinmo^UAS.fl

(Flaherty et al., 2010)

cyst progenitor cell | adult stage | ectopic | increased number, with chinmo^UAS.fl

(Flaherty et al., 2010)

cyst progenitor cell | increased number, with E(z)^HMS00066

(Eun et al., 2014)

cyst progenitor cell | increased number, with hop^Tum.UAS

(Leatherman and DiNardo, 2008)

hub cell | decreased number, with Dp^GD4444

(Herrera et al., 2021)

male germline cell | adult stage, with dsx^RNAi.UAS

(Ma et al., 2014)

male germline cell | adult stage | ectopic | increased number, with chinmo^UAS.fl

(Flaherty et al., 2010)

male germline cell | increased number, with Scer\GAL80^ts.αTub84B, upd1^UAS.cZa

(Leatherman and DiNardo, 2008)

male germline cell | increased number, with Scer\GAL80^ts.αTub84B, zfh1^UAS.cPa

(Leatherman and DiNardo, 2008)

male germline stem cell | increased number, with hop^Tum.UAS

(Leatherman and DiNardo, 2008)

seminal vesicle, with Cdc42^NIG.12530R

(Rotkopf et al., 2011)

seminal vesicle, with sns^GD65

(Rotkopf et al., 2011)

seminal vesicle, with Vrp1^KK111261

(Rotkopf et al., 2011)

seminal vesicle, with WASp^KK102768

(Rotkopf et al., 2011)

somatic cell of testis | adult stage, with chinmo^HM04048

(Ma et al., 2014)

somatic cell of testis | adult stage, with dsx^RNAi.UAS

(Ma et al., 2014)

somatic cell of testis | increased number, with Scer\GAL80^ts.αTub84B, upd1^UAS.cZa

(Leatherman and DiNardo, 2008)

somatic cell of testis | increased number, with Scer\GAL80^ts.αTub84B, zfh1^UAS.cPa

(Leatherman and DiNardo, 2008)

spermatid cyst, with Cdc42^NIG.12530R

(Rotkopf et al., 2011)

spermatid cyst, with sns^GD65

(Rotkopf et al., 2011)

spermatid cyst, with Vrp1^KK111261

(Rotkopf et al., 2011)

spermatid cyst, with WASp^KK102768

(Rotkopf et al., 2011)

testis, with alien^HM05119

(Qian et al., 2015)

testis, with CSN1b^JF02612

(Qian et al., 2015)

testis, with CSN3^HMS00242

(Qian et al., 2015)

testis, with CSN4^GL01169

(Qian et al., 2015)

testis, with CSN5^JF03159

(Qian et al., 2015)

testis, with CSN6^HMS02392

(Qian et al., 2015)

testis, with CSN7^HMS00073

(Qian et al., 2015)

testis, with Cul2^HM05237

(Qian et al., 2015)

testis, with hop^Tum.UAS

(Leatherman and DiNardo, 2008)

testis, with Scer\GAL80^ts.αTub84B, upd1^UAS.cZa

(Leatherman and DiNardo, 2008)

testis, with Scer\GAL80^ts.αTub84B, zfh1^UAS.cPa

(Leatherman and DiNardo, 2008)

testis | adult stage, with chinmo^HM04048

(Ma et al., 2014)

testis | adult stage, with dsx^RNAi.UAS

(Ma et al., 2014)

testis | adult stage, with Sumo^JF02869

(Rinehart et al., 2024)

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scer\GAL4^A3.eya

Name Synonyms

Secondary FlyBase IDs

References (14)

Report Sections

Open Close