FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term male germline stem cell ID (Ontology) FBbt:00004929 (Fly Anatomy)
Definition Male germline cell and stem cell from which all other male germline cells develop. Male germline stem cells are part of the germinal proliferation center of the testis. They are arranged around a central hub made up of densely packed hub cells (apical cells), to which they are attached via adherens junctions.[ FlyBase:FBrf0064778 FlyBase:FBrf0190226 ]
Also Known As "male GSC"
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Annotations
Records annotated with this term OR any of its CHILD TERMS

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Direct annotations: records annotated with this exact term (child terms are NOT included)
Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Insertions (FBti)EXPRESSION_STAGE_TISSUE_POSITION
Insertions (FBti)PHENOTYPE_MANIFEST_IN
Constructs (FBtp)PHENOTYPE_MANIFEST_IN
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Insertions Constructs
 male germline stem cell (all annotations which use CV term, excluding "NOT" statements)
     male germline stem cell | absent
      --       --
     male germline stem cell | absent | adult stage
      --       --
     male germline stem cell | absent | heat sensitive
      --       --       --
     male germline stem cell | adult stage
      --
     male germline stem cell | adult stage | decreased number
      --       --
     male germline stem cell | adult stage | germline clone
      --
      --
     male germline stem cell | adult stage | germline clone | progressive
      --
      --
     male germline stem cell | adult stage | heat sensitive
      --       --
     male germline stem cell | adult stage | progressive
      --
      --
     male germline stem cell | adult stage | somatic clone
      --
      --
     male germline stem cell | calorie restriction conditional
      --       --       --
     male germline stem cell | cell autonomous | germline clone
      --
      --
     male germline stem cell | cell non-autonomous | decreased number
      --       --
     male germline stem cell | decreased number
      --
     male germline stem cell | decreased number | germline clone
      --       --       --
     male germline stem cell | decreased number | larval stage
      --       --       --
     male germline stem cell | decreased number | somatic clone
      --       --       --
     male germline stem cell | ectopic
      --
      --
     male germline stem cell | ectopic | increased number
      --       --
     male germline stem cell | germline clone
      --
      --
     male germline stem cell | heat sensitive
      --
     male germline stem cell | increased number
      --       --
     male germline stem cell | larval stage
      --       --       --
     male germline stem cell | progressive
      --
     male germline stem cell | second instar larval stage
      --
      --
     male germline stem cell | somatic clone
      --
     male germline stem cell | somatic clone | spermatogenesis
      --       --       --
     male germline stem cell | spermatogenesis
      --       --
     male germline stem cell | third instar larval stage
      --
Spanning Tree (Parents/Children)
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Vocabulary search
germline cell
 |__germline stem cell_____________
 |__male germline cell_____________|
testis                             |
 |__germinal proliferation center__|
multi-tissue structure             |
 |__germinal proliferation center__|
stem cell                          |
 |__germline stem cell_____________|
male-specific anatomical entity    |
 |__germinal proliferation center__|
 |__male germline cell_____________|
                                   male germline stem cell  448 rec.
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Is a germline stem cell
male germline cell
Part of germinal proliferation center
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CL:0000016