FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\B4UAS.cSa
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General Information
Symbol
Dmel\B4UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Sotillos
FlyBase ID
FBal0083614
Feature type
allele
Associated gene
Dmel\B4
Associated Insertion(s)
Carried in Construct
P{UAS-B4.S}
Also Known As
UAS-B4
Key Links
Transgenic product class
cDNA
(Sotillos et al., 1997)
wild_type
(Sotillos et al., 1997)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Sotillos et al., 1997)
wild_type
(Sotillos et al., 1997)
Mutagen
in vitro construct
(Sotillos et al., 1997)
Progenitor genotype
Carried in construct
P{UAS-B4.S}
Cytology
Description

A 5.6kb BamHI fragment of B4 cDNA is expressed under the control of UASt regulatory sequences.

(Sotillos et al., 1997)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
B4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Adults expressing B4UAS.cSa under the control of Scer\GAL4Fer2.2359 show a decrease in the number of PAM neurons.

      (Miozzo et al., 2022)

      B4Scer\UAS.cSa; Scer\GAL4GMR.PF flies have small eyes.

      (Wittwer et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      B4UAS.cSa is a suppressor of hyperplasia phenotype of InRact.UAS, Scer\GAL4GMR.PF

      (Wittwer et al., 2005)

      B4UAS.cSa is a suppressor of hyperplasia phenotype of InRUAS.cHa, Scer\GAL4GMR.PF

      (Wittwer et al., 2005)

      B4UAS.cSa is a suppressor of lethal | embryonic stage phenotype of InRUAS.cHa, Scer\GAL4en-e16E

      (Wittwer et al., 2005)
      NOT Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      B4UAS.cSa is a suppressor of eye phenotype of InRact.UAS, Scer\GAL4GMR.PF

      (Wittwer et al., 2005)
      NOT Suppressor of
      Statement
      Reference

      B4UAS.cSa is a non-suppressor of eye phenotype of AktUAS.Tag:HA,Tag:MyrPalm(Lck), Scer\GAL4GMR.PF

      (Wittwer et al., 2005)

      B4UAS.cSa is a non-suppressor of eye phenotype of Pi3K92EUAS.Tag:MYC,Tag:PM(hKRAS), Scer\GAL4GMR.PF

      (Wittwer et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The massive overgrowth of eyes caused InRScer\UAS.cHa or InRact.Scer\UAS with Scer\GAL4GMR.PF flies is suppressed by B4Scer\UAS.cSa. However, B4Scer\UAS.cSa fails to suppress similar overgrowth phenotypes due to Pi3K92EScer\UAS.T:Hsap\MYC,T:Hsap\CAAX or Akt1Scer\UAS.T:Ivir\HA1,T:Uuuu\MyrPalm1 with Scer\GAL4GMR.PF.

      (Wittwer et al., 2005)
      Complementation and Rescue Data
      Partially rescues

      B4UAS.cSa/Scer\GAL4C-765 partially rescues B4k01405

      (Sotillos et al., 1997)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      B4Scer\UAS.cSa
      B4UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Sotillos
      (Sotillos et al., 1997)
      Secondary FlyBase IDs
        References (3)