FlyBase Allele Report: Dmel\B4[k01405]

General Information

Symbol

Dmel\B4^k01405

Species

D. melanogaster

Name

FlyBase ID

FBal0083613

Feature type

allele

Associated gene

Dmel\B4

Associated Insertion(s)

P{lacW}kuz^k01405

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Roch et al., 1998, Sotillos et al., 1997)

Progenitor genotype

Associated Insertion(s)

P{lacW}kuz^k01405

Cytology

Description

Insertion of a P{lacW} element 892bp upstream of the 5' end of the cDNA.

(Sotillos et al., 1997)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

2L:13,550,212..13,550,212 [-]

(Ashburner et al., 1999, Roch et al., 1998, Sotillos et al., 1997)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of P-stage | recessive

(Sotillos et al., 1997)

lethal - all die before end of pupal stage | recessive

(Roch et al., 1998)

some die during pharate adult stage | recessive

(Sotillos et al., 1997)

some die during pupal stage | recessive

(Roch et al., 1998)

visible | recessive

(Roch et al., 1998)

Phenotype Manifest In

imaginal disc

(Roch et al., 1998)

wing

(Roch et al., 1998)

wing vein

(Roch et al., 1998)

Detailed Description

Statement

Reference

Mutants exhibit visible disc abnormalities: discs are small. Clones induced in wild type discs are abnormal: cell differentiation is affected, clones in the wing cause N-like phenotypes, vein thickening and scalloping, the effect is fully autonomous.

(Roch et al., 1998)

The low viability of B4^k01405 homozygotes is partially rescued by B4^Scer\UAS.cSa expressed under the control of Scer\GAL4^C-765.

(Sotillos et al., 1997)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescued by

B4^k01405 is partially rescued by B4^UAS.cSa/Scer\GAL4^C-765

(Sotillos et al., 1997)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

14/5

(Roch et al., 1998)

B4^k01405

k01405

(Ashburner et al., 1999)

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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