FlyBase Allele Report: Dmel\ND-51[HMS01590]

General Information

Symbol

Dmel\ND-51^HMS01590

Species

D. melanogaster

Name

FlyBase ID

FBal0266497

Feature type

allele

Associated gene

Dmel\ND-51

Associated Insertion(s)

Carried in Construct

P{TRiP.HMS01590}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Ni et al., 2011.7.19)

Mutagen

in vitro construct

(Ni et al., 2011.7.19)

Progenitor genotype

Carried in construct

P{TRiP.HMS01590}

Cytology

Description

UAS regulatory sequences drive expression of a short inverted repeat.

(Ni et al., 2011.7.19)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

dsRNA-HMS01590

Also carries

loxP

recombinase target site

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by l(2)gl⁴

(Kurelac et al., 2019)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval fat body | third instar larval stage, with Scer\GAL4^Cg.PA

(Zhou et al., 2019)

eye, with Scer\GAL4^eya.enh1+E+2

(Pletcher et al., 2019)

ganglion mother cell | decreased number | larval stage, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

intermediate neuronal progenitor | decreased number | larval stage, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

larval brain, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

larval brain, with Scer\GAL4^wor.PA

(Verma et al., 2026)

larval muscle cell, with Scer\GAL4^Mhc.F3-580

(Verma et al., 2026)

larval neuroblast, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

larval neuroblast, with Scer\GAL4^wor.PA

(Verma et al., 2026)

larval neuron | decreased number, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

mitochondrial crista, with Scer\GAL4^wor.PA

(Verma et al., 2026)

mitochondrial crista | decreased number | larval stage, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

mitochondrion, with Scer\GAL4^wor.PA

(Verma et al., 2026)

mitochondrion | larval stage, with Scer\GAL4^Mhc.F3-580

(Verma et al., 2026)

mitochondrion | larval stage, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

mitochondrion | third instar larval stage, with Scer\GAL4^Cg.PA

(Zhou et al., 2019)

type II neuroblast | larval stage, with Scer\GAL4^pnt-14-94

(Verma et al., 2026)

Detailed Description

Statement

Reference

Expression under the control of Scer\GAL4^eya.enh1+E+2 results in a glossy eye phenotype.

(Pletcher et al., 2019)

Expressing ND-51^HMS01590 under the control of Scer\GAL4^Cg.PA leads to swollen mitochondria in the third instar larval fat body (as assessed by MitoGFP).

(Zhou et al., 2019)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has decreased occurrence of cell division | larval stage phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has decreased cell number | larval stage phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has decreased cell number | larval stage phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has decreased occurrence of cell division | larval stage phenotype, suppressible | partially by Sod2^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has decreased cell number | larval stage phenotype, suppressible by N^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

NOT Enhancer of

Statement

Reference

ND-51^HMS01590, Scer\GAL4^wor.PA is a non-enhancer of increased occurrence of cell division | larval stage phenotype of Drp1^SD.UASp, Scer\GAL4^wor.PA

(Verma et al., 2026)

Suppressor of

Statement

Reference

ND-51^HMS01590, Scer\GAL4^unspecified is a suppressor | partially of increased cell number phenotype of N^UAS.cMa, Scer\GAL4^unspecified

(Verma et al., 2026)

NOT Suppressor of

Statement

Reference

ND-51^HMS01590, Scer\GAL4^wor.PA is a non-suppressor of increased occurrence of cell division | larval stage phenotype of Drp1^SD.UASp, Scer\GAL4^wor.PA

(Verma et al., 2026)

Other

Statement

Reference

Drp1^SD.UASp, ND-51^HMS01590, Scer\GAL4^wor.PA has increased occurrence of cell division | larval stage phenotype

(Verma et al., 2026)

Phenotype Manifest In

Suppressed by

Statement

Reference

ND-51^HMS01590, Scer\GAL4^Mhc.F3-580 has mitochondrion | larval stage phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^Mhc.F3-580

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^Mhc.F3-580 has larval muscle cell phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^Mhc.F3-580

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has type II neuroblast | larval stage phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has intermediate neuronal progenitor | larval stage | decreased number phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has ganglion mother cell | larval stage | decreased number phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has larval neuron | decreased number phenotype, suppressible | partially by Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^wor.PA has mitochondrion phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^wor.PA

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^wor.PA has mitochondrial crista phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^wor.PA

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^wor.PA has larval neuroblast phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^wor.PA

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has intermediate neuronal progenitor | larval stage | decreased number phenotype, suppressible | partially by Sod2^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has neuron | decreased number phenotype, suppressible by Sod2^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has mitochondrion | larval stage phenotype, suppressible by N^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has larval neuroblast phenotype, suppressible by N^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has intermediate neuronal progenitor | larval stage | decreased number phenotype, suppressible by N^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has ganglion mother cell | larval stage | decreased number phenotype, suppressible by N^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has larval neuron | decreased number phenotype, suppressible | partially by N^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has mitochondrial crista | larval stage | decreased number phenotype, suppressible by Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 has type II neuroblast | larval stage phenotype, suppressible | partially by Sod2^UAS.cMa, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

NOT Enhancer of

Statement

Reference

ND-51^HMS01590, Scer\GAL4^wor.PA is a non-enhancer of larval neuroblast phenotype of Drp1^SD.UASp, Scer\GAL4^wor.PA

(Verma et al., 2026)

Suppressor of

Statement

Reference

ND-51^HMS01590, Scer\GAL4^unspecified is a suppressor | partially of type II neuroblast | increased number phenotype of N^UAS.cMa, Scer\GAL4^unspecified

(Verma et al., 2026)

ND-51^HMS01590, Scer\GAL4^pnt-14-94 is a suppressor of mitochondrial crista | increased number | larval stage phenotype of Drp1^SD.UASp, Scer\GAL4^pnt-14-94

(Verma et al., 2026)

NOT Suppressor of

Statement

Reference

ND-51^HMS01590, Scer\GAL4^wor.PA is a non-suppressor of larval neuroblast phenotype of Drp1^SD.UASp, Scer\GAL4^wor.PA

(Verma et al., 2026)

Other

Statement

Reference

Drp1^SD.UASp, ND-51^HMS01590, Scer\GAL4^wor.PA has larval neuroblast phenotype

(Verma et al., 2026)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

36701

y¹ sc^* v¹ sev²¹; P{TRiP.HMS01590}attP2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

CG9140^HMS01590

ND-51^HMS01590

ND51^HMS01590

Name Synonyms

Secondary FlyBase IDs

References (11)

Report Sections

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