FB2026_03 , released September 17, 2026
FB2026_03 , released September 17, 2026
CV Term Report
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General Information
Term lamellocyte ID (Ontology) FBbt:00001687 (Fly Anatomy)
Definition Hemocyte of the larva that is large, flat and regularly shaped and is involved encapsulation as part of the immune response. They contain short and narrow vesicles of rough endoplasmic reticulum, a well developed Golgi apparatus and some free ribosomes. Lamellocytes are not found in embryos and adults, and are rare in healthy larvae, although their differentiation can be induced by parasitoid wasp infection. Lamellocytes are involved in encapsulating and killing parasites. They differentiate both from the lymph gland and from the sessile hemocyte population. They express atilla (Cattenoz et al., 2020).[ FlyBase:FBrf0031012 FlyBase:FBrf0037631 FlyBase:FBrf0134542 FlyBase:FBrf0144807 FlyBase:FBrf0207538 FlyBase:FBrf0212461 FlyBase:FBrf0245988 ]
Comment Lamellocytes have been suggested to differentiate from plasmatocytes (Stofanko et al., 2010).
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Data ClassFieldDirect annotations
Alleles (FBal)PHENOTYPE_MANIFEST_IN
Insertions (FBti)EXPRESSION_STAGE_TISSUE_POSITION
Insertions (FBti)PHENOTYPE_MANIFEST_IN
Constructs (FBtp)PHENOTYPE_MANIFEST_IN
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 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes  Insertions Constructs
 lamellocyte (all annotations which use CV term, excluding "NOT" statements)
     lamellocyte | cell non-autonomous | larval stage | somatic clone | increased number
      --       --       --
     lamellocyte | cell non-autonomous | somatic clone | third instar larval stage
      --       --
     lamellocyte | conditional | larval stage
      --       --       --       --
     lamellocyte | conditional | third instar larval stage
      --       --       --       --
     lamellocyte | decreased number
      --       --       --
     lamellocyte | decreased number | larval stage
      --       --       --
     lamellocyte | decreased number | larval stage | conditional
      --       --       --
     lamellocyte | ectopic
      --       --       --       --
     lamellocyte | heat sensitive
      --       --       --
     lamellocyte | increased number
      --       --       --
     lamellocyte | increased number | larval stage
      --       --       --
     lamellocyte | increased number | larval stage | conditional
      --       --       --
     lamellocyte | increased number | larval stage | somatic clone
      --       --       --       --
     lamellocyte | increased number | third instar larval stage
      --       --       --
     lamellocyte | larval stage
      --       --
     lamellocyte | larval stage | conditional
      --       --       --
     lamellocyte | larval stage | increased number
      --       --       --
     lamellocyte | larval stage | progressive
      --       --
      --
     lamellocyte | second instar larval stage | increased number
      --       --       --       --
     lamellocyte | third instar larval stage
      --       --
     lamellocyte | third instar larval stage | conditional
      --       --       --
Spanning Tree (Parents/Children)
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germ layer derivative
 |__mesodermal derivative______
larval circulatory system      |
 |__embryonic/larval hemocyte__|
hemocyte                       |
 |__embryonic/larval hemocyte__|
                               lamellocyte  249 rec.
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Is a embryonic/larval hemocyte
mesodermal derivative
Develops from prolamellocyte
Part of
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Synonyms
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CL:0000396