Open Close
General Information
Symbol
Scer\GAL4Mhc.PW
Species
S. cerevisiae
Name
Myosin heavy chain promoter construct of Winberg
FlyBase ID
FBal0058793
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
Mhc-Gal4, Myosin heavy chain-Gal4, MHC82-gal4, MHC Gal4, MHC, (MHC)-GAL4
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

Mhc promoter regulates expression of a GAL4 driver.

Allele components
Product class / Tool use(s)
Regulatory region(s)
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
Additional Information
Statement
Reference

Drives expression in larval and adult muscle.

Expressed in all muscles.

 
Marker for
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In

indirect flight muscle & mitochondrion, with Hsap\PABPN117ala.UAS

indirect flight muscle & nucleus, with Hsap\PABPN117ala.UAS

indirect flight muscle & nucleus, with Hsap\PABPN1ΔCLD.17ala.UAS

indirect flight muscle & nucleus, with Hsap\PABPN1ΔC-term.17ala.UAS

larval abdominal segment 6 & larval somatic muscle, with Hsap\FOXO1::Hsap\PAX7UAS.cGa

larval somatic muscle & cell, with Hsap\FOXO1::Hsap\PAX7UAS.cGa

Detailed Description
Statement
Reference

Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4Mhc.PW cells in larvae does not affect the speed of peristalsis, compared to controls.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Enhanced by
Statement
Reference
NOT Enhanced by
Statement
Reference
Suppressed by
Statement
Reference

Pink1dsRNA.UAS, Scer\GAL4Mhc.PW has short lived phenotype, suppressible by Keap1EY1/Keap1[+]

Pink1dsRNA.UAS, Scer\GAL4Mhc.PW has short lived phenotype, suppressible by Keap1EY5/Keap1[+]

NOT suppressed by
Statement
Reference

Scer\GAL4Mhc.PW, ThorLL.UAS has long lived phenotype, non-suppressible by foxo21/foxo[+]

Pink1dsRNA.UAS, Scer\GAL4Mhc.PW has visible phenotype, non-suppressible by Keap1EY1/Keap1[+]

Pink1dsRNA.UAS, Scer\GAL4Mhc.PW has visible phenotype, non-suppressible by Keap1EY5/Keap1[+]

Enhancer of
Statement
Reference
NOT Enhancer of
Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference

cluUASp.cSa/Scer\GAL4Mhc.PW is a non-suppressor of visible phenotype of park25

Scer\GAL4Mhc.PW/Hsap\CLUHUASp.cSa is a non-suppressor of visible phenotype of park25

NGD14477/Scer\GAL4Mhc.PW is a non-suppressor of visible | progressive phenotype of Pink1B9

Scer\GAL4Mhc.PW/NGD144 is a non-suppressor of visible | progressive phenotype of Pink1B9

Phenotype Manifest In
Enhanced by
Statement
Reference

Hsap\FOXO1::Hsap\PAX7UAS.cGa, Scer\GAL4Mhc.PW has larval somatic muscle & cell phenotype, enhanceable by Ras85DV12.UAS, Scer\GAL4Mhc.PW

Suppressed by
Statement
Reference
NOT suppressed by
Statement
Reference

Pink1dsRNA.UAS, Scer\GAL4Mhc.PW has wing phenotype, non-suppressible by Keap1EY1/Keap1[+]

Pink1dsRNA.UAS, Scer\GAL4Mhc.PW has wing phenotype, non-suppressible by Keap1EY5/Keap1[+]

Enhancer of
Statement
Reference

Ras85DV12.UAS, Scer\GAL4Mhc.PW is an enhancer of larval somatic muscle & cell phenotype of Hsap\FOXO1::Hsap\PAX7UAS.cGa, Scer\GAL4Mhc.PW

Suppressor of
Statement
Reference
NOT Suppressor of
Statement
Reference

NGD14477/Scer\GAL4Mhc.PW is a non-suppressor of wing | progressive phenotype of Pink1B9

Scer\GAL4Mhc.PW/NGD144 is a non-suppressor of wing | progressive phenotype of Pink1B9

Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Fails to rescue
Comments
Images (0)
Mutant
Wild-type
Stocks (6)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
GAL4Mhc.PW
Scer\GAL4Mhc.PW
Name Synonyms
Myosin heavy chain promoter construct of Winberg
Secondary FlyBase IDs
    References (157)