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General Information
Symbol
Dmel\SmoxJF02320
Species
D. melanogaster
Name
FlyBase ID
FBal0220688
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Allele class
Nature of the Allele
Allele class
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Carried in construct
Cytology
Nature of the lesion
Statement
Reference

UAS regulatory sequences drive expression of an inverted repeat.

Allele components
Product class / Tool use(s)
Encoded product / tool
Associated Sequence Features
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Scer\GAL4αTub84B.Switch.PK SmoxJF02320 adults, fed with RU486 to activate expression, show extended lifespan compared to controls.

Scer\GAL4Mhc.PW SmoxJF02320 adults, but not Scer\GAL4Switch1.106 SmoxJF02320 adults, show extended lifespan compared to controls.

Scer\GAL4Mhc.PW-mediated expression of SmoxJF02320 retards the normal decline in flight activity seen in aging flies, and delays the normal increase in protein aggregates and the normal decrease in lysosomes/autophagic vacuoles within muscle.

Scer\GAL4Mhc.PW-mediated expression of SmoxJF02320 does not affect female fecundity.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
SmoxJF02320
Name Synonyms
Secondary FlyBase IDs
    References (4)