FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Aberration: Dmel\Df(3L)BSC12
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General Information
Symbol
Df(3L)BSC12
Species
D. melanogaster
Name
FlyBase ID
FBab0029722
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 69F6--70A2
Genomic Maps
Sequence coordinates
3L:13,044,488..13,044,488 (Df(3L)BSC12:bk1)
(Cook, 2016.2.8)
3L:13,227,765..13,227,765 (Df(3L)BSC12:bk2)
(Cook, 2016.2.8)
Member of large scale dataset(s)
Dfs_BSC_set1

A set of ~50 targeted deficiencies created by exploiting hybrid element insertion (HEI) and resolution; designed to fill gaps in deletion coverage.

(Parks et al., 2004)
Nature of Aberration
Cytological Order
Progenitor
P{PZ}Syx1301470
(Parks et al., 2004, Deal and Cook, 2002.1.22)
P{EP}capsEP3557
(Parks et al., 2004, Deal and Cook, 2002.1.22)
Mutagen
Delta2-3 transposase
(Deal and Cook, 2002.1.22)
mitotic recombination
(Deal and Cook, 2002.1.22)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Parks et al., 2004, Deal and Cook, 2002.1.22)
Breakpoints

69F6-70A1;70A1-70A2

(Parks et al., 2004, Deal and Cook, 2002.1.22)
Causes alleles
Carries alleles
e1
(Deal and Cook, 2002.1.22)
rhove-1
(Deal and Cook, 2002.1.22)
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

The 3L:13044488 release 6 coordinate of the left breakpoint is an estimate. It corresponds to the insertion site of P{PZ}Syx1301470. As FBrf0175003 explains, deletions generated by P transposase in the presence of trans-heterozygous P elements are expected to extend from the end of one P insertion to the vicinity of the other P insertion. The absence of miniwhite from the Df(3L)BSC12 chromosome suggests that the deletion extends from the right end of the P{PZ}Syx1301470 insertion to the vicinity of P{EP}capsEP3557. Heterozygotes for Df(3L)BSC12 do not show Minute phenotypes, so the haploinsufficient RpS4 gene lies to the left of this breakpoint.

(Cook, 2016.2.8)

The 3L:13227765 release 6 coordinate of the right breakpoint is an estimate. It corresponds to the insertion site of P{EP}capsEP3557. As FBrf0175003 explains, deletions generated by P transposase in the presence of trans-heterozygous P elements are expected to extend from the end of one P insertion to the vicinity of the other P insertion. The absence of miniwhite from the Df(3L)BSC12 chromosome suggests that the deletion extends from the right end of the P{PZ}Syx1301470 insertion to the vicinity of P{EP}capsEP3557.

(Cook, 2016.2.8)
Comments on Cytology

The 70A1,2 doublet appears attenuated, but not absent. The 70A4,5 doublet and 69F5 are present, but the 69F6, 69F7 and 70A3 bands are not visible.

(Deal and Cook, 2002.1.22)
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
trn
(Deal and Cook, 2002.1.22)
Partially deleted / disrupted
Molecular Data
Completely deleted
Partially deleted
Genes NOT Deleted / Disrupted
Complementation Data
 
Poc1
(Blachon et al., 2009)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (21)
Phenotypic Data
In combination with other aberrations
NOT in combination with other aberrations

The salivary gland distal tip does not initiate turning and migration in embryos homozygous for Df(3L)BSC12 by stage 14.

(Jattani et al., 2009)
Stocks (2)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 

The miniwhite markers from P{lacW} and P{EP}EP1090 were deleted or disrupted based on the w- eye color of flies carrying the deletion chromosome in the presence of w1.

(Deal and Cook, 2002.1.22)
Synonyms and Secondary IDs (1)
References (18)