FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Mob4UAS.cSa
Open Close
General Information
Symbol
Dmel\Mob4UAS.cSa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Schulte
FlyBase ID
FBal0246738
Feature type
allele
Associated gene
Dmel\Mob4
Associated Insertion(s)
Carried in Construct
P{UAS-Mob4.S}
Key Links
Transgenic product class
cDNA
(Schulte et al., 2010)
wild_type
(Schulte et al., 2010)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Schulte et al., 2010)
wild_type
(Schulte et al., 2010)
Mutagen
in vitro construct
(Schulte et al., 2010)
Progenitor genotype
Carried in construct
P{UAS-Mob4.S}
Cytology
Description

UAS regulatory sequences drive expression of the Mob4 open reading frame from cDNA LD21194.

(Schulte et al., 2010)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Mob4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4Act.PU/Mob4UAS.cSa rescues Mob4EYΔL3

      (Schulte et al., 2010)
      Partially rescues

      Scer\GAL4elav-C155/Mob4UAS.cSa partially rescues Mob4EYΔL3

      (Schulte et al., 2010)
      Fails to rescue

      Scer\GAL4Mhc.PW/Mob4UAS.cSa fails to rescue Mob4EYΔL3

      (Schulte et al., 2010)
      Comments

      Expression of Mob4Scer\UAS.cSa under the control of Scer\GAL4Act.PU rescues the larval lethality of Mob4EYΔL3 homozygotes; the rescued animals being able to pupate and eclose as adults.

      Expression of Mob4Scer\UAS.cSa under the control of Scer\GAL4elav-C155 partially rescues the larval lethality of Mob4EYΔL3 homozygotes; the rescued animals are able to pupate but do not eclose as adults.

      Expression of Mob4Scer\UAS.cSa under the control of Scer\GAL4elav-C155 partially rescues the supernumerary bouton phenotype observed at the neuromuscular junction in Mob4EYΔL3 mutant larvae.

      Expression of Mob4Scer\UAS.cSa under the control of Scer\GAL4elav-C155 rescues the EPSC phenotype of seen at the neuromuscular junction in Mob4EYΔL3 larvae, but expression of Mob4Scer\UAS.cSa under the control of Scer\GAL4Mhc.PW does not rescue this phenotype.

      Expression of Mob4Scer\UAS.cSa under the control of Scer\GAL4Mhc.PW fails to rescue the larval lethality of Mob4EYΔL3 homozygotes.

      (Schulte et al., 2010)
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Mob4Scer\UAS.cSa
      Mob4UAS.cSa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Schulte
      Secondary FlyBase IDs
        References (2)