FlyBase Allele Report: Dmel\TBPH[NIG.10327R]

General Information

Symbol

Dmel\TBPH^NIG.10327R

Species

D. melanogaster

Name

FlyBase ID

FBal0270425

Feature type

allele

Associated gene

Dmel\TBPH

Associated Insertion(s)

Carried in Construct

P{NIG.10327R}

Key Links

Genomic Maps

JBrowse

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

RNAi_reagent

(Japanese National Institute of Genetics, 2012.5.21)

Mutagen

in vitro construct

(Japanese National Institute of Genetics, 2012.5.21)

Progenitor genotype

Carried in construct

P{NIG.10327R}

Cytology

Description

UASt regulatory sequences drive expression of a 500bp inverted repeat.

(Japanese National Institute of Genetics, 2012.5.21)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

dsRNA-10327R

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates myotonic dystrophy type 1

modeled by Zzzz\CTG^i480.UAS.cGa

(Llamusi et al., 2013)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of TBPH^NIG.10327R under the control of Scer\GAL4^elav-C155 has no effect on bouton size.

(Deivasigamani et al., 2014)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/TBPH^NIG.10327R is a suppressor of abnormal neuroanatomy phenotype of Scer\GAL4^elav-C155, Vap33^P58S.cRa.UAS

(Deivasigamani et al., 2014)

Scer\GAL4^sca.PU/TBPH^NIG.10327R is a suppressor of visible phenotype of Scer\GAL4^sca.PU, Vap33^UAS.cRa

(Deivasigamani et al., 2014)

Phenotype Manifest In

Enhancer of

Statement

Reference

TBPH^NIG.10327R/Scer\GAL4^GMR.PU is an enhancer of eye phenotype of Scer\GAL4^GMR.PU, mbl^C.UAS

(Llamusi et al., 2013)

Scer\GAL4^hs.2sev/TBPH^NIG.10327R is an enhancer of eye phenotype of Scer\GAL4^hs.2sev, mbl^C.UAS

(Llamusi et al., 2013)

Suppressor of

Statement

Reference

Scer\GAL4^elav-C155/TBPH^NIG.10327R is a suppressor of terminal bouton phenotype of Scer\GAL4^elav-C155, Vap33^P58S.cRa.UAS

(Deivasigamani et al., 2014)

Scer\GAL4^sca.PU/TBPH^NIG.10327R is a suppressor of macrochaeta phenotype of Scer\GAL4^sca.PU, Vap33^UAS.cRa

(Deivasigamani et al., 2014)

TBPH^NIG.10327R/Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\CTG^i480.UAS.cGa

(Llamusi et al., 2013)

Scer\GAL4^vg.PU/TBPH^NIG.10327R is a suppressor of wing phenotype of Scer\GAL4^vg.PU, Zzzz\CTG^i480.UAS.cGa

(Llamusi et al., 2013)

Scer\GAL4^Mhc.PW/TBPH^NIG.10327R is a suppressor of indirect flight muscle cell phenotype of Scer\GAL4^Mhc.PW, Zzzz\CTG^i480.UAS.cGa

(Llamusi et al., 2013)

Additional Comments

Genetic Interactions

Statement

Reference

Expression of TBPH^NIG.10327R suppresses the loss of bristle phenotype seen when Vap-33A^Scer\UAS.cRa is expressed under the control of Scer\GAL4^sca.PU.

Expression of TBPH^NIG.10327R suppresses the enlarged bouton phenotype seen when Vap-33A^{P58S.cRa.Scer\UAS} is expressed under the control of Scer\GAL4^elav-C155.

(Deivasigamani et al., 2014)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

TBPH^NIG.10327R

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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