FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\bratUAS.Tag:FLAG
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General Information
Symbol
Dmel\bratUAS.Tag:FLAG
Species
D. melanogaster
Name
FlyBase ID
FBal0288446
Feature type
allele
Associated gene
Dmel\brat
Associated Insertion(s)
Carried in Construct
P{UAS-FLAG-brat}
Key Links
Transgenic product class
cDNA
(Shi et al., 2013)
wild_type
(Shi et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Shi et al., 2013)
wild_type
(Shi et al., 2013)
Mutagen
in vitro construct
(Shi et al., 2013)
Progenitor genotype
Carried in construct
P{UAS-FLAG-brat}
Cytology
Description

UAS regulatory sequences drive expression of the brat coding sequence (from cDNA clone LD16270) which is tagged with Tag:FLAG.

(Shi et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
brat
Tagged with
Tag:FLAG
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4RapGAP1-OK6/bratUAS.Tag:FLAG partially rescues brat2L-192-9/brat11

      (Shi et al., 2013)

      Scer\GAL4elav.PU/bratUAS.Tag:FLAG partially rescues brat2L-192-9/brat11

      (Shi et al., 2013)
      Fails to rescue

      bratUAS.Tag:FLAG/Scer\GAL4Mhc.PW fails to rescue brat2L-192-9/brat11

      (Shi et al., 2013)
      Comments

      Expression of bratScer\UAS.T:Zzzz\FLAG under the control of either Scer\GAL4elav.PU or Scer\GAL4RapGAP1-OK6 at 18[o]C partially rescues the increase in number of satellite boutons at the neuromuscular junction (NMJ) seen in brat11/brat2L-192-9 larvae. Expression under the control of Scer\GAL4Mhc.PW at 18[o]C does not rescue the NMJ phenotype.

      Expression of bratScer\UAS.T:Zzzz\FLAG under the control of Scer\GAL4elav.PU at 18[o]C partially rescues the endocytotic defects seen at the NMJ of brat11/brat2L-192-9 larvae.

      (Shi et al., 2013)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      bratScer\UAS.T:Zzzz\FLAG
      bratUAS.Tag:FLAG
      Name Synonyms
      Secondary FlyBase IDs
        References (1)