FlyBase Allele Report: Dmel\Chchd2[S81L.UAS]

UASt regulatory sequences drive expression of Chchd2 that carries a S81L amino acid substitution. This change is equivalent to a S59L change in the orthologous human CHCHD10 gene, a pathogenic variant.

(Baek et al., 2021)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Chchd2

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

point_mutation

X:17,150,028..17,150,028 [+]

Nucleotide change:

C17150028T

Amino acid change:

S81L | Chchd2-PA; S33L | Chchd2-PB

Reported amino acid change:

S81L

Comment:

Analogous S59L mutation in human CHCHD10 implicated in frontotemporal dementia and/or amyotrophic lateral sclerosis 2; mutation carried on in vitro construct; site of nucleotide substitution in fly gene inferred by FlyBase curator based on reported amino acid change.

(Baek et al., 2021)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of frontotemporal dementia and/or amyotrophic lateral sclerosis 2

CEA

(Baek et al., 2021)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of frontotemporal dementia and/or amyotrophic lateral sclerosis 2

is exacerbated by Marf^KK105681

(Baek et al., 2021)

is ameliorated by Marf^UAS.cUa

(Baek et al., 2021)

is exacerbated by Miro^JF02775

(Baek et al., 2021)

is exacerbated by Mitofilin^GD4642

(Baek et al., 2021)

is exacerbated by Mitofilin^KK107998

(Baek et al., 2021)

is ameliorated by Mitofilin^{T507A.T561A.UAS.Tag:MYC}

(Baek et al., 2021)

is ameliorated by Pink1^GD11336

(Baek et al., 2021)

is ameliorated by Pink1^HMC04160

(Baek et al., 2021)

is ameliorated by Pink1^KK101205

(Baek et al., 2021)

is exacerbated by Atg1^GL00047

(Baek et al., 2021)

is exacerbated by TER94^GD9777

(Baek et al., 2021)

is exacerbated by Atg1^HMS02750

(Baek et al., 2021)

is ameliorated by park^GD5543

(Baek et al., 2021)

is exacerbated by Atg1^JF02273

(Baek et al., 2021)

is ameliorated by park^HMS01800

(Baek et al., 2021)

is exacerbated by Atg1^UAS.cSa

(Baek et al., 2021)

is ameliorated by park^KK107919

(Baek et al., 2021)

is exacerbated by Drp1^GD10456

(Baek et al., 2021)

is exacerbated by Drp1^HMC03230

(Baek et al., 2021)

is exacerbated by Drp1^JF02762

(Baek et al., 2021)

is ameliorated by Drp1^UAS.cDa

(Baek et al., 2021)

is ameliorated by Hsap\CHCHD10^UAS.cBa

(Baek et al., 2021)

is exacerbated by Hsap\PINK1^{G309D.UAS.Tag:FLAG}

(Baek et al., 2021)

is exacerbated by Marf^GD11094

(Baek et al., 2021)

is exacerbated by Marf^HMC03883

(Baek et al., 2021)

is exacerbated by Marf^JF01650

(Baek et al., 2021)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

This allele represents a human variant implicated in disease.

(Baek et al., 2021)

CHCHD10:p.Ser59Leu

(FlyBase curators, 2019-)

Variants Synonym(s)

Associated human disease model(s)

frontotemporal dementia and/or amyotrophic lateral sclerosis 2

External database links

ClinVar: 140745

Comments concerning this variant

Phenotypic Data

Phenotypic Class

abnormal eye color | adult stage | progressive, with Scer\GAL4^GMR.PU

(Baek et al., 2021)

abnormal flight, with Scer\GAL4^Mhc.PW

(Baek et al., 2021)

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^VGlut1-OK371

(Baek et al., 2021)

fertile, with Scer\GAL4^VGlut1-OK371

(Baek et al., 2021)

viable, with Scer\GAL4^VGlut1-OK371

(Baek et al., 2021)

visible | adult stage, with Scer\GAL4^GMR.PU

(Baek et al., 2021)

visible | adult stage, with Scer\GAL4^Mhc.PW

(Baek et al., 2021)

visible | adult stage | progressive, with Scer\GAL4^GMR.PU

(Baek et al., 2021)

Phenotype Manifest In

embryonic/larval neuromuscular junction | third instar larval stage, with Scer\GAL4^VGlut1-OK371

(Baek et al., 2021)

eye, with Scer\GAL4^GMR.PU

(Baek et al., 2021)

indirect flight muscle cell | adult stage, with Scer\GAL4^Mhc.PW

(Baek et al., 2021)

mitochondrion | adult stage, with Scer\GAL4^Mhc.PW

(Baek et al., 2021)

NMJ bouton | decreased number | third instar larval stage, with Scer\GAL4^VGlut1-OK371

(Baek et al., 2021)

sarcomere | adult stage, with Scer\GAL4^Mhc.PW

(Baek et al., 2021)

wing, with Scer\GAL4^Mhc.PW

(Baek et al., 2021)

Detailed Description

Statement

Reference

The expression from one copy of Chchd2^S81L.UAS under the control of Scer\GAL4^GMR.PU induces eye degeneration, with a rough eye and depigmentation as the flies aged. Expression from two copies of Chchd2^S81L.UAS leads to more severe eye phenotypes, which are present from eclosion.

The expression from two copies of Chchd2^S81L.UAS under the control of Scer\GAL4^VGlut-OK371 leads to fewer boutons and branches at the third instar larval neuromuscular junction.

The expression from one copy of Chchd2^S81L.UAS under the control of Scer\GAL4^Mhc.PW induces a 'held-up' wing phenotype, decreased flight ability and sarcomeric defects in adult indirect flight muscles. The expression from two copies of Chchd2^S81L.UAS leads to 45-days-old adults showing indirect flight muscle defects, with mitochondria fragmentation.

(Baek et al., 2021)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Marf^GD11094, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Drp1^JF02762, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Drp1^GD10456, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by TER94^GD9777, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Marf^JF01650, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Mitofilin^GD4642, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Mitofilin^KK107998, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Marf^HMC03883, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Marf^KK105681, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, enhanceable by Drp1^HMC03230, Scer\GAL4^GMR.PU

(Baek et al., 2021)

NOT Enhanced by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by ari-1^JF03352, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by Mitofilin^UAS.Tag:MYC, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by ND-42^UAS.Tag:HA, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by mud^GL00629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by ref(2)P^HMS00551, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by mib2^HMJ21843, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by Tango11², Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by ref(2)P^HMS00938, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by mib1^JF02629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by mud^HMS01458, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by key^GL00088, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by key^HMC04952, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by mud^JF02911, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by sicily^mCherry, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by sicily^UAS.cZa, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-enhanceable by BNIP3^HMJ02058, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Suppressed by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible by Hsap\CHCHD10^UAS.cBa, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible | partially by Pink1^GD11336, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible | partially by park^GD5543, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible by Pink1^HMC04160, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible by Pink1^KK101205, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible | partially by park^KK107919, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible | partially by park^HMS01800, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^Mhc.PW has visible | adult stage phenotype, suppressible | partially by Pink1^GD11336, Scer\GAL4^Mhc.PW

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^Mhc.PW has abnormal flight phenotype, suppressible | partially by Pink1^GD11336, Scer\GAL4^Mhc.PW

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, suppressible | partially by Mitofilin^{T507A.T561A.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Baek et al., 2021)

NOT suppressed by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by ari-1^JF03352, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by Mitofilin^UAS.Tag:MYC, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by key^GL00088, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by key^HMC04952, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by mud^JF02911, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by sicily^mCherry, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by sicily^UAS.cZa, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by BNIP3^HMJ02058, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by ND-42^UAS.Tag:HA, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by mud^GL00629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by ref(2)P^HMS00551, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by mib2^HMJ21843, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by Tango11², Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by ref(2)P^HMS00938, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by mib1^JF02629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has visible | adult stage | progressive phenotype, non-suppressible by mud^HMS01458, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Other

Statement

Reference

Chchd2^S81L.UAS, Drp1^UAS.cDa, Scer\GAL4^GMR.PU has lethal phenotype

(Baek et al., 2021)

Atg1^UAS.cSa, Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has lethal phenotype

(Baek et al., 2021)

Phenotype Manifest In

Enhanced by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Marf^GD11094, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Drp1^JF02762, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Drp1^GD10456, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by TER94^GD9777, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Mitofilin^GD4642, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Mitofilin^KK107998, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Marf^JF01650, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Marf^HMC03883, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Marf^KK105681, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, enhanceable by Drp1^HMC03230, Scer\GAL4^GMR.PU

(Baek et al., 2021)

NOT Enhanced by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by ari-1^JF03352, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Mitofilin^UAS.Tag:MYC, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by ND-42^UAS.Tag:HA, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by mud^GL00629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by ref(2)P^HMS00551, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by mib2^HMJ21843, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by Tango11², Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by ref(2)P^HMS00938, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by mib1^JF02629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by mud^HMS01458, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by key^GL00088, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by key^HMC04952, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by mud^JF02911, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by sicily^mCherry, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by sicily^UAS.cZa, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-enhanceable by BNIP3^HMJ02058, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Suppressed by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Hsap\CHCHD10^UAS.cBa, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Pink1^GD11336, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by park^GD5543, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Pink1^HMC04160, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible by Pink1^KK101205, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by park^KK107919, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by park^HMS01800, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^Mhc.PW has indirect flight muscle cell | adult stage phenotype, suppressible | partially by Pink1^GD11336, Scer\GAL4^Mhc.PW

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^Mhc.PW has mitochondrion | adult stage phenotype, suppressible | partially by Pink1^GD11336, Scer\GAL4^Mhc.PW

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^Mhc.PW has wing phenotype, suppressible | partially by Pink1^GD11336, Scer\GAL4^Mhc.PW

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, suppressible | partially by Mitofilin^{T507A.T561A.UAS.Tag:MYC}, Scer\GAL4^GMR.PU

(Baek et al., 2021)

NOT suppressed by

Statement

Reference

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by ari-1^JF03352, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Mitofilin^UAS.Tag:MYC, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by key^GL00088, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by mib2^HMJ21843, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by ref(2)P^HMS00938, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by Tango11², Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by key^HMC04952, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by mud^GL00629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by mib1^JF02629, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by mud^HMS01458, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by mud^JF02911, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by ND-42^UAS.Tag:HA, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by ref(2)P^HMS00551, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by sicily^mCherry, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by sicily^UAS.cZa, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Chchd2^S81L.UAS, Scer\GAL4^GMR.PU has eye phenotype, non-suppressible by BNIP3^HMJ02058, Scer\GAL4^GMR.PU

(Baek et al., 2021)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

Chchd2^S81L.UAS is rescued by Chchd2^UAS.cBa/Scer\GAL4^GMR.PU

(Baek et al., 2021)

Partially rescued by

Chchd2^S81L.UAS is partially rescued by Scer\GAL4^Mhc.PW/Chchd2^UAS.cBa

(Baek et al., 2021)

Not rescued by

Chchd2^S81L.UAS is not rescued by Chchd2^null

(Baek et al., 2021)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Chchd2^S81L.UAS

Name Synonyms

Secondary FlyBase IDs

References (2)

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