FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\ND-42UAS.Tag:HA
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General Information
Symbol
Dmel\ND-42UAS.Tag:HA
Species
D. melanogaster
Name
FlyBase ID
FBal0284125
Feature type
allele
Associated gene
Dmel\ND-42
Associated Insertion(s)
Carried in Construct
PBac{UAS-ND-42-HA}
Also Known As
UAS-ND42-HA
Key Links
Transgenic product class
cDNA
(Zhang et al., 2013)
wild_type
(Zhang et al., 2013)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Zhang et al., 2013)
wild_type
(Zhang et al., 2013)
Mutagen
in vitro construct
(Zhang et al., 2013)
Progenitor genotype
Carried in construct
PBac{UAS-ND-42-HA}
Cytology
Description

UAS regulatory sequences drive expression of the ND-42 coding sequence (derived from the LD29280 cDNA clone), which is tagged with a Tag:HA epitope.

(Zhang et al., 2013)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
ND-42
Tagged with
Tag:HA
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      DOES NOT ameliorate  Parkinson's disease
      modeled by park25
      (Pogson et al., 2014)
      ameliorates  Parkinson's disease
      modeled by Pink1B9
      (Pogson et al., 2014)
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of ND-42Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.PU has no effect on climbing or flight behavior.

      (Pogson et al., 2014)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      NOT Enhancer of
      Suppressor of
      NOT Suppressor of
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      ND-42UAS.Tag:HA, Scer\GAL4GMR.PU is a non-enhancer of eye phenotype of Chchd2S81L.UAS, Scer\GAL4GMR.PU

      (Baek et al., 2021)
      NOT Suppressor of
      Statement
      Reference

      ND-42UAS.Tag:HA, Scer\GAL4GMR.PU is a non-suppressor of eye phenotype of Chchd2S81L.UAS, Scer\GAL4GMR.PU

      (Baek et al., 2021)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Ubiquitous expression of ND-42Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.PU restores climbing and flight ability in Pink1B9 mutant flies.

      Ubiquitous expression of ND-42Scer\UAS.T:Ivir\HA1 under the control of Scer\GAL4da.PU does not rescue the climbing and flight defects seen in park25 mutant flies.

      (Pogson et al., 2014)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      ND-42Scer\UAS.T:Ivir\HA1
      ND-42UAS.Tag:HA
      ND42Scer\UAS.T:Ivir\HA1
      Name Synonyms
      Secondary FlyBase IDs
        References (3)