Homozygous larval instar eye imaginal discs show a number of defects in morphology and glial cell migration; in some cases glial cells are found anterior to the morphogenetic furrow and appear to migrate in a broad stream onto the eye imaginal disc, while in others, only a relatively thin stream of of glial cells overshoot anterior to the morphogenetic furrow. Hemizygous eye discs show defects where a duplication of the morphogenetic furrow and the corresponding field of photoreceptor neurons is seen at 90[o] to the normal eye field.
65% of spinEP822/spink09905 stage 14 egg chambers show persisting nurse cell nuclei, compared to 7% in controls. 24% of egg chambers display a dumpless phenotype where nurse cell cytoplasm has not been transferred to the oocyte.
77% of spink09905 germ line clone stage 14 egg chambers show persisting nurse cell nuclei. 14% of egg chambers display a dumpless phenotype where nurse cell cytoplasm has not been transferred to the oocyte.
Mutation is lethal at the pharate pupal stage. spink09905/+, spin10403/spink09905 and spink09905/Df(2R)Jp4 animals show a significant increase in bouton number at the larval neuromuscular junction (assayed at muscles 6/7 in hemisegment A3) compared to wild type. Quantal content at the neuromuscular junction is decreased by approximately 50% compared to wild type in spin10403/spink09905 animals. Quantal size is unaffected. Only 23% of spin10403/spink09905 animals are adult viable.