FlyBase Aberration Report: Dmel\Df(2R)twi

General Information

Symbol

Df(2R)twi

Species

D. melanogaster

Name

Deficiency (2R) twist

FlyBase ID

FBab0002232

Feature type

chromosomal_deletion

Also Known As

Df(2R)twi^S60, Df(2R)S60, twi^S60, Df(1)S60

Computed Breakpoints include

59C3-59C4;59D1-59D2

Features within 59C3--59D2

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

X ray

(Simpson, 1983)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

Breakpoints

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

bk1 << twi << bk2

Genetic mapping information

Comments

Breakpoint(s) molecularly mapped

(Thisse et al., 1987)

Comments on Cytology

All limits from polytene analysis (citation unavailable)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

twi

(Ip et al., 1994, Jaglarz and Howard, 1994, Leptin, 1991, Leiss et al., 1988)

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

ord

(Moore, 1997)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location (0)

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Related Comments

Phenotypic Data

In combination with other aberrations

Inferred to overlap with: Df(2R)WI3117.

(Moore, 1997)

NOT in combination with other aberrations

In twi, sna double mutant embryos the primordial germ cells exit the gut primordium relatively normally and migrate dorsally towards the surface of the pocket which would normally appose the mesoderm.

(Jaglarz and Howard, 1994)

Patches of wild type cells injected into a twi,sna double mutant embryos undergo typical ventral shape changes, nuclear movements and apical constrictions, as long as they are in a region that would normally be occupied by prospective mesoderm.

(Leptin and Roth, 1994)

Embryos mutant for both sna and twi do not form an anterior midgut or a stomodeum.

(Reuter and Leptin, 1994)

Defective in gonad assembly when in double mutant combination with sna.

(Warrior, 1994)

Homozygous females lay dorsalised eggs.

(Leiss et al., 1988)

Stocks (2)

Bloomington

6147

Df(2R)twi, Adc^b-1 pr¹ cn¹ bw¹/CyO

Kyoto

108647

Df(2R)twi, Adc^b-1 pr¹ cn¹ bw¹/CyO

Notes on Origin

Discoverer

P. Simpson.

(Simpson, 1983)

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

Synonyms and Secondary IDs (10)

Reported As

Symbol Synonym

Df(1)S60

(Leptin and Roth, 1994, Reuter and Leptin, 1994)

Df(1)twi-S60

(Lindsley and Zimm, 1992)

Df(2R)S60

(Seher et al., 2007, San Martin and Bate, 2001, Casal and Leptin, 1996, Warrior, 1994, Leptin, 1991, Leiss et al., 1988)

Df(2R)twi

(Galindo et al., 2014, Seher et al., 2007)

Df(2R)twi-S60

(Moore, 1997)

Df(2R)twi^S60

(Melendez et al., 1995, Costa et al., 1994, Arora and Nusslein-Volhard, 1992, Leptin et al., 1992, Leptin and Grunewald, 1990, Thisse et al., 1988, Thisse et al., 1987, Simpson, 1983)

twi^S60

(Jazwinska et al., 1999, Hortsch et al., 1998, Goubeaud et al., 1996, Ip et al., 1994, Rao et al., 1991)

twi^s60

twist^Df560

(Großhans and Wieschaus, 2000)

Name Synonyms

Deficiency (2R) twist

Secondary FlyBase IDs

FBal0035888

References (28)

Report Sections

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