FlyBase Allele Report: Dmel\TrpA1[lexAop.cBa]

General Information

Symbol

Dmel\TrpA1^lexAop.cBa

Species

D. melanogaster

Name

Escherichia coli lexAop construct a of Burke

FlyBase ID

FBal0283999

Feature type

allele

Associated gene

Dmel\TrpA1

Associated Insertion(s)

Carried in Construct

P{lexAop-TrpA1.B}

Also Known As

LexAop-TRPA1, LexAop-dTrpA1

Key Links

Transgenic product class

wild_type

(Burke et al., 2012)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Burke et al., 2012)

Mutagen

in vitro construct

(Burke et al., 2012)

Progenitor genotype

Carried in construct

P{lexAop-TrpA1.B}

Cytology

Description

lexAop regulatory sequences drive expression of TrpA1.

(Burke et al., 2012)

Allele components

Component

Use(s)

Regulatory region(s)

lexAop

binary expression system - regulatory region

Encoded product / tool

TrpA1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of TrpA1^{Ecol\lexAop.cBa} under the control of Ecol\lexA^{Tdc2.T:Hsim\VP16} at 31[o]C contingent with odour presentation is sufficient to form robust appetitive olfactory memory in hungry flies.

(Burke et al., 2012)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT Enhanced by

Statement

Reference

Ecol\lexA^{GAD.ple.Tag:NLS(SV40-largeT)}, TrpA1^lexAop.cBa has abnormal locomotor behavior | adult stage | heat sensitive phenotype, non-enhanceable by Scer\GAL4^238Y/Dop1R2^GD703

(Sun et al., 2018)

Suppressed by

Statement

Reference

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Scer\GAL4^Myo31DF.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Cat^UAS.cAa/Scer\GAL4^mex1.PU

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Cat^UAS.cAa/Scer\GAL4^Myo31DF.PU

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible | partially by Cat^UAS.cAa/Scer\GAL4^elav.PU

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible | partially by Scer\GAL4^elav.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible | partially by Scer\GAL4^elav.PU/Sod2^UAS.cMa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has increased cell death | adult stage phenotype, suppressible by Scer\GAL4^mex1.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has abnormal stress response | adult stage phenotype, suppressible by Scer\GAL4^mex1.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has increased cell death | adult stage phenotype, suppressible by Scer\GAL4^Myo31DF.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has abnormal stress response | adult stage phenotype, suppressible by Scer\GAL4^Myo31DF.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR68A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Cat^UAS.cAa/Scer\GAL4^Myo31DF.PU

(Vaccaro et al., 2020)

Ecol\lexA^GMR68A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Scer\GAL4^Myo31DF.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR68A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Scer\GAL4^Myo31DF.PU/Sod2^UAS.cMa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Scer\GAL4^mex1.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Scer\GAL4^mex1.PU/Sod2^UAS.cMa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has short lived phenotype, suppressible by Scer\GAL4^Myo31DF.PU/Sod2^UAS.cMa

(Vaccaro et al., 2020)

Ecol\lexA^{GAD.ple.Tag:NLS(SV40-largeT)}, TrpA1^lexAop.cBa has abnormal locomotor behavior | adult stage | heat sensitive phenotype, suppressible by Scer\GAL4^238Y/Dop1R1^HMC05200

(Sun et al., 2018)

Ecol\lexA^{GAD.ple.Tag:NLS(SV40-largeT)}, TrpA1^lexAop.cBa has abnormal locomotor behavior | adult stage | heat sensitive phenotype, suppressible | partially by Scer\GAL4^GMR35B12/Dop1R1^HMC05200

(Sun et al., 2018)

Ecol\lexA^{GAD.ple.Tag:NLS(SV40-largeT)}, TrpA1^lexAop.cBa has abnormal locomotor behavior | adult stage | heat sensitive phenotype, suppressible | partially by Scer\GAL4^GMR16A06/Dop1R1^HMC05200

(Sun et al., 2018)

NOT suppressed by

Statement

Reference

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has decreased sleep | adult stage | heat sensitive phenotype, non-suppressible by Cat^UAS.cAa/Scer\GAL4^elav.PU

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has decreased sleep | adult stage | heat sensitive phenotype, non-suppressible by Scer\GAL4^elav.PU/Sod1^UAS.cWa

(Vaccaro et al., 2020)

Ecol\lexA^GMR50A07, TrpA1^lexAop.cBa has decreased sleep | adult stage | heat sensitive phenotype, non-suppressible by Scer\GAL4^elav.PU/Sod2^UAS.cMa

(Vaccaro et al., 2020)

Ecol\lexA^{GAD.ple.Tag:NLS(SV40-largeT)}, TrpA1^lexAop.cBa has abnormal locomotor behavior | adult stage | heat sensitive phenotype, non-suppressible by Scer\GAL4^238Y/Dop1R2^GD703

(Sun et al., 2018)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Expression of TrpA1^{Ecol\lexAop.cBa} under the control of Ecol\lexA^{Tdc2.T:Hsim\VP16} at 31[o]C contingent with odour presentation does not induce appetitive olfactory memory in hungry flies if the flies are also carrying Scer\GAL4^c061, Scer\GAL80^Mef2.PT and Octβ2R^KK109808 (to knock down Octβ2R expression in the MB-MP1 neurons).

(Burke et al., 2012)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

TrpA1^{Ecol\lexAop.cBa}

TrpA1^lexAop.cBa

Name Synonyms

Escherichia coli lexAop construct a of Burke

Secondary FlyBase IDs

References (12)

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