FB2026_02 , released June 18, 2026
Allele: Scer\GAL4GMR35B12
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General Information
Symbol
Scer\GAL4GMR35B12
Species
S. cerevisiae
Name
FlyBase ID
FBal0251810
Feature type
allele
Associated gene
Scer\GAL4
Associated Insertion(s)
Carried in Construct
P{GMR35B12-GAL4}
Also Known As
R35B12-Gal4, R35B12, GMR35B12-GAL4
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Pfeiffer et al., 2011.2.9)
Progenitor genotype
Carried in construct
P{GMR35B12-GAL4}
Cytology
Description

A 3073 base pair fragment from the flanking non-coding or intronic region of Abd-B is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Allele components
Component
Use(s)
Regulatory region(s)
GMR35B12
Encoded product / tool
GAL4
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Inhibition (using shi1.UAS at 32[o]C) of Scer\GAL4GMR35B12 cells in adults does not affect startle-induced climbing behavior, compared to controls.

      Thermogenetic activation (using TrpA1UAS.(B).cKa at 32[o]C) of Scer\GAL4GMR35B12 cells in adults significantly reduces startle-induced climbing behavior, compared to controls; thermogenetic activation of the combined set of Scer\GAL4GMR35B12 and Scer\GAL4Mef2.247 cells in adults slightly, but significantly, reduces startle-induced climbing behavior, compared to controls, but this phenotype is significantly less severe than activation of Scer\GAL4GMR35B12 cells alone.

      (Sun et al., 2018)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Scer\GAL4GMR35B12
      Name Synonyms
      Secondary FlyBase IDs
        References (16)