FlyBase Allele Report: Dmel\Pi3K92E[D954A.UAS.Tag:MYC]

General Information

Symbol

Dmel\Pi3K92E^{D954A.UAS.Tag:MYC}

Species

D. melanogaster

Name

FlyBase ID

FBal0058398

Feature type

allele

Associated gene

Dmel\Pi3K92E

Associated Insertion(s)

Carried in Construct

P{Dp110^D954A}

Also Known As

UAS-Pi3K^DN, UAS-Dp110^DN, Dp110^D954A, UAS-dp110^D954A, UAS-Dp110DN, UAS-PI3KDN, PI3K^D954A, UAS-Dp110^KD, UAS-PI3K^D954A, Dp110^DN

Key Links

Transgenic product class

missense_variant

(Leevers et al., 1996)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

missense_variant

(Leevers et al., 1996)

Mutagen

in vitro construct

(Leevers et al., 1996)

Progenitor genotype

Carried in construct

P{Dp110^D954A}

Cytology

Description

UASt regulatory sequences drive expression of a Pi3K92E cDNA fragment, with a mutation (D954A) introduced the putative ATP binding site. The open reading frame is tagged at the N-terminal end with Tag:MYC.

(Leevers et al., 1996)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Pi3K92E

Tagged with

Tag:MYC

epitope tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

ameliorates cancer

modeled by dlg1^GD4689, Ras85D^V12.UAS

(Katheder et al., 2017)

exacerbates Parkinson's disease

modeled by DJ-1α^RNAi.UAS

(Yang et al., 2005)

exacerbates Huntington's disease

modeled by Hsap\HTT^{Q138.UAS.mRFP1}

(Hansen et al., 2019)

ameliorates high grade glioma

modeled by Wdr62^UAS.Tag:HA

(Shohayeb et al., 2020)

ameliorates fragile X syndrome

modeled by Fmr1³

(Monyak et al., 2017)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal cell death | embryonic stage, with Scer\GAL4^unspecified

(Scanga et al., 2000)

abnormal cell shape, with Scer\GAL4^Cg.PU

(Molina et al., 2022)

abnormal cell size, with Scer\GAL4^amn-c651

(Caldwell et al., 2005)

abnormal cell size, with Scer\GAL4^ccb-796

(Martin-Pena et al., 2006)

abnormal developmental rate, with Scer\GAL4^amn-c651

(Lin et al., 2011)

abnormal developmental rate, with Scer\GAL4^P0206

(Colombani et al., 2005)

abnormal developmental rate | third instar larval stage, with Scer\GAL4^amn-c651

(Caldwell et al., 2005)

abnormal developmental rate | third instar larval stage, with Scer\GAL4^amn-X8

(Caldwell et al., 2005)

abnormal locomotor behavior, with Scer\GAL4^ccb-796

(Martin-Pena et al., 2006)

abnormal neuroanatomy, with Scer\GAL4^C57

(Mozer and Sandstrom, 2012)

abnormal neuroanatomy, with Scer\GAL4^GH298

(Acebes et al., 2011)

abnormal neuroanatomy, with Scer\GAL4^GH298, Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

abnormal neuroanatomy, with Scer\GAL4^GH298, Scer\GAL80^ChAT.3.3P

(Acebes et al., 2011)

abnormal neuroanatomy, with Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

abnormal neuroanatomy, with Scer\GAL4^{kra-krasavietz}, Scer\GAL80^Mef2.mb247

(Acebes et al., 2011)

abnormal neuroanatomy, with Scer\GAL4^Mef2.247

(Acebes et al., 2011)

abnormal neuroanatomy, with Scer\GAL4^Toll-6-D42

(Mozer and Sandstrom, 2012, Chun-Jen Lin et al., 2011, Martin-Pena et al., 2006)

abnormal neurophysiology, with Scer\GAL4^C57

(Mozer and Sandstrom, 2012)

abnormal neurophysiology, with Scer\GAL4^Toll-6-D42

(Mozer and Sandstrom, 2012)

abnormal size, with Scer\GAL4^Bx-MS1096

(Marygold et al., 2011)

abnormal size, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

abnormal size | cell autonomous, with Scer\GAL4^dpp.blk1

(Resino and Garcia-Bellido, 2004)

abnormal size | cell non-autonomous, with Scer\GAL4^dpp.blk1

(Resino and Garcia-Bellido, 2004)

abnormal size | third instar larval stage, with Scer\GAL4^hh.PU

(Romero-Pozuelo et al., 2017)

abnormal smell perception, with Scer\GAL4^GH298

(Acebes et al., 2011)

abnormal smell perception, with Scer\GAL4^GH298, Scer\GAL80^ChAT.3.3P

(Acebes et al., 2011)

abnormal smell perception, with Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

abnormal smell perception, with Scer\GAL4^{kra-krasavietz}, Scer\GAL80^Mef2.mb247

(Acebes et al., 2011)

abnormal wound healing, with Scer\GAL4^crq.PO

(Wood et al., 2006)

chemical resistant | RU486 conditional, with Scer\GAL4^da.Switch.PT

(Slack et al., 2011)

decreased body size | nutrition conditional, with Scer\GAL4^ppl.PP

(Kamakura, 2011)

decreased cell number, with Scer\GAL4^dpp.blk1

(Resino and Garcia-Bellido, 2004, Goberdhan et al., 1999)

decreased cell number, with Scer\GAL4^GMR.PF

(Kramer et al., 2003)

decreased cell number, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

decreased cell number | third instar larval stage, with Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

decreased cell size, with Scer\GAL4^ap-md544

(Resino and Garcia-Bellido, 2004)

decreased cell size, with Scer\GAL4^Bx-MS1096

(Gao et al., 2000)

decreased cell size, with Scer\GAL4^dpp.blk1

(Resino and Garcia-Bellido, 2004, Goberdhan et al., 1999)

decreased cell size, with Scer\GAL4^GMR.PF

(Kramer et al., 2003)

decreased cell size, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

decreased cell size, with Scer\GAL4^ppl.PP

(Liu et al., 2014)

decreased fecundity | female | RU486 conditional, with Scer\GAL4^da.Switch.PT

(Slack et al., 2011)

decreased occurrence of cell division | adult stage | RU486 conditional, with Scer\GAL4^bun-GSG5961

(Biteau et al., 2010)

decreased size | third instar larval stage, with Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

increased body size, with Scer\GAL4^P0206

(Colombani et al., 2005)

increased body size | adult stage, with Scer\GAL4^amn-c651

(Caldwell et al., 2005)

increased body size | pupal stage, with Scer\GAL4^amn-c651

(Caldwell et al., 2005)

increased body size | pupal stage, with Scer\GAL4^amn-X8

(Caldwell et al., 2005)

increased cell number, with Scer\GAL4^ccb-796

(Martin-Pena et al., 2006)

increased cell number, with Scer\GAL4^P0206

(Colombani et al., 2005)

long lived | RU486 conditional, with Scer\GAL4^bun-GSG5961

(Biteau et al., 2010)

long lived | RU486 conditional, with Scer\GAL4^da.Switch.PT

(Slack et al., 2011)

short lived, with Scer\GAL4^NP5130, Scer\GAL80^ts.αTub84B

(Biteau et al., 2010)

viable | RU486 conditional, with Scer\GAL4^da.Switch.PT

(Slack et al., 2011)

visible, with Scer\GAL4^Bx-MS1096

(Coelho et al., 2005, Bohni et al., 1999, Goberdhan et al., 1999)

visible, with Scer\GAL4^dpp.blk1

(Porstmann et al., 2008, Resino and Garcia-Bellido, 2004, Miron et al., 2001, Goberdhan et al., 1999)

visible, with Scer\GAL4^ey.PH

(Scanga et al., 2000)

visible, with Scer\GAL4^GMR.PF

(Junger et al., 2003)

visible | embryonic stage, with Scer\GAL4^unspecified

(Scanga et al., 2000)

Phenotype Manifest In

adult gut, with Scer\GAL4^NP5130, Scer\GAL80^ts.αTub84B

(Biteau et al., 2010)

adult gut | RU486 conditional, with Scer\GAL4^bun-GSG5961

(Biteau et al., 2010)

adult mushroom body, with Scer\GAL4^{kra-krasavietz}, Scer\GAL80^ple.PK

(Acebes et al., 2011)

adult mushroom body, with Scer\GAL4^Tab2-201Y

(Acebes et al., 2012)

antennal lobe, with Scer\GAL4^GH298

(Acebes et al., 2011)

antennal lobe, with Scer\GAL4^GH298, Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

antennal lobe, with Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

antennal lobe glomerulus DM2, with Scer\GAL4^GH298, Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2012)

antennal lobe glomerulus DM2, with Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2012)

axon, with Scer\GAL4^Toll-6-D42

(Chun-Jen Lin et al., 2011)

bouton, with Scer\GAL4^C57

(Mozer and Sandstrom, 2012)

bouton, with Scer\GAL4^Toll-6-D42

(Mozer and Sandstrom, 2012)

chaeta, with Scer\GAL4^ap-md544

(Resino and Garcia-Bellido, 2004)

embryonic/first instar larval cuticle, with Scer\GAL4^unspecified

(Scanga et al., 2000)

embryonic/larval salivary gland, with Scer\GAL4^ppl.PP

(Liu et al., 2014)

eye, with Scer\GAL4^Bx-MS1096

(Bohni et al., 1999)

eye, with Scer\GAL4^ey.PH

(Scanga et al., 2000)

eye, with Scer\GAL4^GMR.PF

(Junger et al., 2003, Leevers et al., 1996)

eye, with Scer\GAL4^P0206

(Colombani et al., 2005)

first posterior wing cell, with Scer\GAL4^dpp.blk1

(Miron et al., 2001)

first posterior wing cell, with Scer\GAL4^ptc-559.1

(Cho et al., 2001)

germ band, with Scer\GAL4^Kr.PM

(Herranz et al., 2006)

hemocyte, with Scer\GAL4^Cg.PU

(Molina et al., 2022)

imaginal disc & cell, with Scer\GAL4^Act5C.PP

(Weinkove et al., 1999)

interneuron, with Scer\GAL4^GH298

(Acebes et al., 2011)

interneuron, with Scer\GAL4^GH298, Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

interneuron, with Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

interneuron, with Scer\GAL4^Mef2.247

(Acebes et al., 2011)

larval brain | third instar larval stage, with Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

larval glial cell | decreased number | third instar larval stage, with Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

mesonotum, with Scer\GAL4^ap-md544

(Resino and Garcia-Bellido, 2004)

mesonotum | pupal stage | somatic clone, with Scer\GAL4^FRT.Act5C

(Levayer et al., 2015)

motor neuron, with Scer\GAL4^Toll-6-D42

(Chun-Jen Lin et al., 2011)

neuron | increased number, with Scer\GAL4^ccb-796

(Martin-Pena et al., 2006)

ommatidium, with Scer\GAL4^GMR.PF

(Leevers et al., 1996)

prothoracic gland, with Scer\GAL4^amn-c651

(Lin et al., 2011, Caldwell et al., 2005)

synapse

(Chun-Jen Lin et al., 2011)

synapse, with Scer\GAL4^C57

(Mozer and Sandstrom, 2012)

synapse, with Scer\GAL4^GH298

(Acebes et al., 2011)

synapse, with Scer\GAL4^GH298, Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

synapse, with Scer\GAL4^{kra-krasavietz}

(Acebes et al., 2011)

synapse, with Scer\GAL4^Mef2.247

(Acebes et al., 2011)

synapse, with Scer\GAL4^Toll-6-D42

(Mozer and Sandstrom, 2012, Martin-Pena et al., 2006)

wing, with Scer\GAL4^Bx-MS1096

(Marygold et al., 2011, Coelho et al., 2005, Coelho et al., 2005, Gao et al., 2000, Bohni et al., 1999, Goberdhan et al., 1999)

wing, with Scer\GAL4^dpp.blk1

(Porstmann et al., 2008, Goberdhan et al., 1999, Leevers et al., 1996)

wing, with Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

wing, with Scer\GAL4^P0206

(Colombani et al., 2005)

wing & cell, with Scer\GAL4^dpp.blk1

(Goberdhan et al., 1999)

wing disc posterior compartment, with Scer\GAL4^en-e16E

(Teleman and Cohen, 2000, Weinkove et al., 1999)

wing disc posterior compartment | third instar larval stage, with Scer\GAL4^hh.PU

(Romero-Pozuelo et al., 2017)

Detailed Description

Statement

Reference

Expression of Pi3K92E^{D954A.UAS.Tag:MYC} under the control of Scer\GAL4^repo.PU leads to a decrease in the brain volume in third instar larvae.

(Shohayeb et al., 2020)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^hh.PU results in decreased size of the posterior compartment in third instar larval wing discs.

(Romero-Pozuelo et al., 2017)

There is an increase in the frequency of clone splitting in the Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}-expressing 'loser' cells when cell competition is induced in the pupal notum through generation of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}-expressing clones in wild type tissues compared with wild type clones in wild type tissue. The 'loser' clones show reduced compactness over time. The maximum speed of relaxation of junctions after laser nanoablation is reduced in loser-loser and loser-winner junctions compared with winner-winner junctions.

(Levayer et al., 2015)

Knockdown of Pi3K92E through the expression of dominant-negative Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^ppl.PP, leads to small cell size (approximately 50% the size of wild-type) and an ectopic lipid storage phenotype in the salivary gland.

(Liu et al., 2014)

Expression of Pi3K92E^{Scer\UAS.T:Hsap\MYC} in the mushroom bodies under the control of Scer\GAL4^Tab2-201Y causes a decrease in the size of the mushroom body lobes and calyces, compared with controls. These synaptic changes do not have a detectable consequence on odour central adaptation.

Expression of Pi3K92E^{Scer\UAS.T:Hsap\MYC} in the projection neurons, under the control of Scer\GAL4^GH146 or Scer\GAL4^{exba-krasavietz}, does not affect central or cross adaptation to EB, IAA and benzaldehyde odours.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in both the eLNs and iLNs, under the control of both Scer\GAL4^GH298 and Scer\GAL4^{exba-krasavietz} results in normal adaption to EB, IAA and benzaldehyde, indicating that olfactory central adaption depends on the eLN/iLN activity ratio.

Coincident odorant-specific DM2 glomerular size change induced by exposure to EB is not detected when Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} is expressed under the control of Scer\GAL4^{exba-krasavietz}. Under the control of both Scer\GAL4^{exba-krasavietz} and Scer\GAL4^GH298, central adaptation is restored, and likewise, the size of DM2 enlarges significantly (+24%) while that of the V glomerulus remains unaffected.

(Acebes et al., 2012)

Subperineurial expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Gli-rL82 in a wild-type genetic background has only a minor effect on larval peripheral nerves.

(Dahlgaard et al., 2012)

Overexpression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in motor neurons, under the control of Scer\GAL4^D42, results in decreased synaptic growth and increased neuronal excitability.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in larval muscle, using Scer\GAL4^C57, results in a decrease in bouton number (by approximately 20%) and muscle size.

In Scer\GAL4^C57>Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} larvae, muscle capacitance is reduced compared to wild-type, consistent with reduced muscle size. The amplitudes of EJCs from Scer\GAL4^C57>Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} are significantly increased, although the frequency, mean amplitude, and distribution of mEJCs are normal.

(Mozer and Sandstrom, 2012)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in 30-32 neurons of the antennal lobe under the control of Scer\GAL4^GH298 reduces neuronal branching. There are no significant changes in cell number in these mutants. The antennal lobe displays reduced activity when exposed to benzaldehyde or isoamylacetate in mutants compared to controls. This reduction is more pronounced in the medial rather than the lateral region of the antennal lobe, for either odorant stimulation. Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} expressing Scer\GAL4^GH298 neurons do not exhibit a preferential branching in the medial antennal lobe; therefore this activity difference may indicate a functional specialization within the branching arbor of the Scer\GAL4^GH298 set of neurons.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in 30-32 neurons of the antennal lobe under the control of Scer\GAL4^GH298 leads to odorant perception changes. Response to benzaldehyde, ethyl hexanoate, ethyl butyrate, and propionic acid shifts towards repulsion. The strength of repulsive reaction is proportional to the odorant concentration.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in 30-32 neurons of the antennal lobe under the control of Scer\GAL4^GH298 in a Scer\GAL80^Cha.3.3P background where Scer\GAL4^GH298-driven expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} is repressed in cha-positive neurons leads to odorant perception changes that are the same as when Scer\GAL80^Cha.3.3P is not present.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in 6-8 neurons of the antennal lobe under the control of Scer\GAL4^{exba-krasavietz} reduces neuronal branching. There are no significant changes in cell number in these mutants.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in 6-8 neurons of the antennal lobe under the control of Scer\GAL4^{exba-krasavietz} leads to odorant perception changes. Response to benzaldehyde, ethyl hexanoate, ethyl butyrate, and propionic acid shifts towards attraction. The strength of attractive reaction is proportional to the odorant concentration. A Scer\GAL80^Cha.3.3P background completely abolishes this attraction. Inhibition of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} expression until the first day of adult life (through the presence of Scer\GAL80^ts.αTub84B) does not alter odorant perception changes compared to flies with chronic Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} expression.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in Scer\GAL4^{exba-krasavietz} and Scer\GAL4^GH298 expressing neurons results in synapse reduction in both sets of neurons and wild-type odorant perception, independent of stimulus.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in Scer\GAL4^{exba-krasavietz} neurons where the mushroom body component of the krasavietz domain is silenced through the presence of Scer\GAL80^Mef2.PT still leads to the increase of olfactory indexes when tested for 1-Hexanol.

Upregulation of Pi3K92E through expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Mef2.247 causes a substantial reduction of neural branching in its MB domain. However, odorant perception is not affected in these mutants.

Silencing of krasavietz mushroom body neurons through expression of Scer\GAL80^ple.PK in Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}/Scer\GAL4^{exba-krasavietz} mutants does not prevent the change in olfactory perception that is characteristic of Scer\GAL4^{exba-krasavietz}-related neurons.

(Acebes et al., 2011)

Blocking Pi3K92E activity in motor neurons by expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in motor neurons under the control of Scer\GAL4^D42 decreases synapse number about two-fold.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in motor neurons under the control of Scer\GAL4^D42 decreases motor axon diameter.

(Chun-Jen Lin et al., 2011)

In contrast to wild-type, transgenic flies expressing Scer\GAL4^ppl.PP>Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} and reared on medium supplemented with Apis mellifera royal jelly do not show increased body size. However, similarly to wild-type flies in response to royal jelly, they display shortened developmental time compared with flies reared on control medium.

(Kamakura, 2011)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^amn-c651 results in a reduction in the size of the prothoracic gland in larvae compared with controls at the equivalent time point of 5 days after egg deposition. These animals show only a moderate developmental delay and pupate, eclosing as larger than normal flies. The defects in developmental rate and adult size are suppressed by feeding 20-hydroxyecdysone to larvae.

(Lin et al., 2011)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} using Scer\GAL4^Bx-MS1096 results in an abnormally small wing.

(Marygold et al., 2011)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} using Scer\GAL4^nub-AC-62 results in abnormally small wings in which cell size and cell number are decreased.

(Resnik-Docampo and de Celis, 2011)

Expression of InR^{K1409A.Scer\UAS} under the control of Scer\GAL4^da.Switch.PT, induced by RU486, increases median lifespan by 7% and maximum lifespan by 5%.

Ubiquitous adult-specific induction of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.Switch.PT decreases female fecundity.

Flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.Switch.PT all survive for significantly longer on food supplemented with 20mM paraquat compared to controls.

Flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.Switch.PT survive for longer in the presence of DTT, compared to controls.

(Slack et al., 2011)

Compared with controls, the age-related dysplasia of the intestinal epithelium is strongly reduced in flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^esg-NP5130 and Scer\GAL80^ts.αTub84B.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^esg-NP5130 and Scer\GAL80^ts.αTub84B results in significant lifespan shortening compared with controls.

Compared with controls, female flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^bun-GSG5961 show a moderate, but significant, reduction in intestinal cell proliferation at old age. These flies are significantly longer lived when exposed to RU486 than isogenic siblings exposed to mock treatment.

(Biteau et al., 2010)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^dpp.blk1 results in a 20-30% decrease in the size of the Scer\GAL4^dpp.blk1-expressing wing compartment.

(Porstmann et al., 2008)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in the amnioserosa cells, driven by Scer\GAL4^Kr.PM, results in the failure of embryos to retract the germ band.

(Herranz et al., 2006)

Larval expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^D42 exhibit a reduction in synapse number compared to wild-type.

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4⁷⁹⁶ does not cause a reduction in synaptic volume. However, there is both a reduction in cell size and an increase in cell number. Supernumerary neurons contribute to an almost normal synaptic domain that compensates for the smaller cell size.

Animals overexpressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in ellipsoid body neurons under the control of Scer\GAL4⁷⁹⁶ are inactive for longer periods and, consequently, walk shorter distances than their sibling controls. The number of full walks is also lower in Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} animals, while walking speed is unaffected.

(Martin-Pena et al., 2006)

Hemocytes expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} (under the control of Scer\GAL4^crq.PO) exhibit normal distribution at all stages of development, and appear morphologically indistinguishable from their wild-type counterparts. Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}-expressing hemocytes migrate along the ventral midline in a pattern identical to that seen in wild-type embryos, demonstrating velocity, directionality, and polarity equal to wild-type cells.

Laser-ablated Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}-expressing embryos (under the control of Scer\GAL4^crq.PO) fail to chemotax toward the wound site and the wound remains largely undetected by the hemocytes up to 1 hour after laser ablation. The same result is obtained when beads are implanted in the embryo. There is no significant different in hemocyte number between Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}-expressing embryos and wild-type.

(Wood et al., 2006)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^amn-c651, results in pupae and adults that are larger than wild-type controls. The wing epidermis of these flies is increased, suggesting that most of this increased size results from increased cell size rather than cell number. Expression of this transgene under the control of Scer\GAL4^amn-X8 causes an increase in pupal length. Flies that express one copy of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}, under the control of one copy of either Scer\GAL4^amn-c651 or Scer\GAL4^amn-X8, pupariate about 36 hours after wild-type controls, which results mostly from a prolonged third instar stage. Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^amn-c651 causes a reduction of prothoracic gland cell size.

(Caldwell et al., 2005)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^Bx-MS1096, reduces wing size.

(Coelho et al., 2005)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Bx-MS1096 results in small adult wings. This phenotype is not affected by null mutations in Pi3K92E.

(Coelho et al., 2005)

When Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} is driven by Scer\GAL4^P0206, animals exhibit increased growth: adults have 17% greater weight on average. This increase was attributable to an increase in cell number in the wing and eye. The timing of embryonic and larval development in these mutants is comparable to controls. The duration of pupal development is advanced by less than four hours. A 1 to 3 hour delay is seen in the time Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} (without driver) mutants enter pupal development.

(Colombani et al., 2005)

Scer\GAL4^GMR.long>Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} mutants show no defects in opsin regulation.

(Mikeladze-Dvali et al., 2005)

When fed ad libitum, third instar larvae expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^NPFR1.6.6 display hyperactive feeding on solid food, similar to control third instar larvae deprived of food for 40 minutes.

(Wu et al., 2005)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}, under the control of Scer\GAL4^GMR.PF has no effect on eye morphology.

(Yang et al., 2005)

Inhibition of PI3K signaling in dopaminergic neurons by means of overexpression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} (through Scer\GAL4^ple.PF) results in an elevation in the levels of reactive oxygen species (ROS).

(Yang, 2005)

Hemocytes in Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}; Scer\GAL4^srp.Hemo late embryos do not exhibit abnormal aggregation.

(Bruckner et al., 2004)

Cells in sector C of the wing expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^dpp.blk1 are 12.6% smaller than control cells. The average area of the mutant sector is reduced by 18.7% compared to controls and the average number of cells in the mutant sector is reduced by 13.3%. In addition to the autonomous reduction in the area of the sector expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^dpp.blk1 (sector C), a non-autonomous reduction of all other wing sectors is seen. In the B sector of mosaic wings the reduction in area is 20%, while the global reduction in area of the wing is 7%. Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^ap-md544 results in a clear decrease in size and number of chaetae compared to controls. In the acrostical region there is an increase in density of microchaetae compared to wild type, which is due to both reduced cell size and fewer cells between the microchaetae than normal (4.16 in mutant tissue compared to 5.34 in wild type).

(Resino and Garcia-Bellido, 2004)

When expression is driven by Scer\GAL4^Lsp2.PH, relatively late in the larval fat body, no effect on autophagic activity of fat droplet aggregation is detectable.

(Rusten et al., 2004)

When expression is driven by Scer\GAL4^GMR.PF eye size is reduced.

(Junger et al., 2003)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PI does not lead to increased larval wandering. Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF results in the formation of relatively normal eyes with fewer and smaller cells.

(Kramer et al., 2003)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Act5C.PP in clones of cells does not promote cell growth or DNA endoreplication. Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Adh.PF, Scer\GAL4^en-e16E or Scer\GAL4^Act5C.PP has no effect on viability under starvation conditions.

(Britton et al., 2002)

The border cells in the ovaries of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}; Scer\GAL4^slbo.2.6 animals form normal numbers and sizes of cellular extensions, and migrate normally.

(Fulga and Rorth, 2002)

When Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} is driven by Scer\GAL4^ptc-559.1 results in a reduction in the distance between the L3 and L4 veins in the wing.

(Cho et al., 2001)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^slbo.2.6 has no effect on border cell migration.

(Duchek and Rorth, 2001)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^dpp.blk1 results in reduction in size of the region encompassed by wing veins 3 and 4, the anterior crossvein and the wing margin.

(Miron et al., 2001)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} driven by Scer\GAL4^Bx-MS1096 results in an decreased wing size.

(Gao et al., 2000)

Expression of high levels of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} in embryos results in ectopic apoptosis and extensive loss of cuticle.

Ectopic expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} driven by Scer\GAL4^ey.PH results in eyes that are smaller in size than that of wild-type controls due to a dramatic decrease in cell number.

(Scanga et al., 2000)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^en-e16E results in a decrease in size of the posterior compartment of the wing disc.

(Teleman and Cohen, 2000)

The targeted expression of the dominant negative Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} by Scer\GAL4^Bx-MS1096 in the developing eye or wing causes a reduction in cell size in the eye, and in both cell size and number in the wing.

(Bohni et al., 1999)

When expression is driven by Scer\GAL4^dpp.blk1 the area between wing veins LIII and LIV is significantly reduced due to a decrease in both cell number and cell size. When expression is driven by Scer\GAL4^Bx-MS1096 the whole wing is significantly reduced in size.

(Goberdhan et al., 1999)

When expression is driven in imaginal disc cells by Scer\GAL4^Act5C.PP the size of the cells is slightly decreased (as measured by FSC (forward scatter)). Overexpression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} is sufficient to reduce the rate of increase of cell number. When expression is driven by Scer\GAL4^en-e16E, the size of the posterior compartment of the wing disc is significantly reduced. There is no comparable effect on the anterior compartment.

(Weinkove et al., 1999)

Scer\GAL4^dpp.blk1 mediated expression caused reduction of the wing margin due to a decrease in cell size. Scer\GAL4^GMR.PF mediated expression causes small and flat eyes.

(Leevers et al., 1996)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi^E90/ebi[+]

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi[+]/ebi^CC3

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi[+]/ebi^CCS-8

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi[+]/ebi^E4

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi^Δ1/ebi[+]

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi[+]/ebi^W418X

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi[+]/ebi^k16213

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi[+]/ebi^WKS-24

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by ebi[+]/ebi^P7

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by E-2g[+]/ebi^2g1

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has abnormal size phenotype, enhanceable by E-2g[+]/ebi^2g2

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 has abnormal size phenotype, enhanceable by hppy^UAS.cMa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 has decreased cell number phenotype, enhanceable by hppy^UAS.cMa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 has decreased cell size phenotype, enhanceable by hppy^UAS.cMa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by chico^flp147E

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by lep^3c5/lep[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by lep^3c6/lep[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by ncm[+]/ncm^2a1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by ncm^2a2/ncm[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by ncm[+]/ncm^SH0931

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by oho23B[+]/RpS21⁰³⁵⁷⁵

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by prp8[+]/Prp8^2e1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Prp8^2e2/prp8[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-2g[+]/ebi^2g1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-2g[+]/ebi^2g2

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by pix^3c3/pix[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by pix^3c2/pix[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)A209/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)C246/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)G4e^LH24i^R/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)HA85/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)HF396/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)JA26/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)JA27/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)KA14/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)KA7/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)N-8/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)N105/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)N19/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)dm75e19/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Df(1)sd72b/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-2c[+]/E-2c^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-2fa[+]/E-2fa²

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-2fb³/E-2fb[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-3c1[+]/E-3c1¹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-3c4[+]/E-3c4⁴

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by E-3c7⁷/E-3c7[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by InR³³⁹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpL38[+]/RpL38^2b1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpL38[+]/RpL38^2b2

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpL5^2d1/RpL5[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpL5^2d2/RpL5[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpLP1[+]/RpLP1^beo

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpS13¹/RpS13[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpS17⁶/RpS17[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpS26⁰⁴⁵⁵³/RpS26[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpS26^KG00230/RpS26[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpS3[+]/RpS3¹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpS3A[+]/RpS3A^57g

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by RpS5a[+]/RpS5a¹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Tor[+]/mTor^ΔP

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, enhanceable by Tor[+]/mTor^2L19

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF has visible phenotype, enhanceable by Hsap\FOXO3^UAS.cFa, Scer\GAL4^GMR.PF

(Junger et al., 2003)

NOT Enhanced by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by Akt1[+]/Akt^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by Pi3K21B^unspecified/Pi3K21B[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by Pten^unspecified/Pten[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by Rheb^unspecified/Rheb[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by Tsc1[+]/Tsc1^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by eIF3h^k09003/eIF-3p40[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by eIF4E1⁰⁷²³⁸/eIF-4E[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by eIF-4a[+]/eIF4A^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-enhanceable by foxo[+]/foxo^unspecified

(Coelho et al., 2005)

Suppressed by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU has decreased size | third instar larval stage phenotype, suppressible | partially by Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU has decreased cell number | third instar larval stage phenotype, suppressible | partially by Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ppl.PP has decreased cell size phenotype, suppressible | partially by Cds^EY08412, Scer\GAL4^ppl.PP

(Liu et al., 2014)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^{kra-krasavietz} has abnormal smell perception phenotype, suppressible by Scer\GAL80^ChAT.3.3P

(Acebes et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^da.Switch.PT has long lived | RU486 conditional phenotype, suppressible by foxo^Δ94

(Slack et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^da.Switch.PT has long lived phenotype, suppressible | partially by Scer\GAL4^da.Switch.PT

(Slack et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, suppressible by Df(1)BA1/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, suppressible by ap[+]/ap^2a1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, suppressible by ap^2a2/ap[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, suppressible | partially by Df(2R)nap1/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ey.PH has visible phenotype, suppressible by Akt^hs.PS, Scer\GAL4^ey.PH

(Scanga et al., 2000)

NOT suppressed by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^{kra-krasavietz} has abnormal smell perception phenotype, non-suppressible by Scer\GAL80^ts.αTub84B

(Acebes et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^da.Switch.PT has viable | RU486 conditional phenotype, non-suppressible by foxo^Δ94

(Slack et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^da.Switch.PT has decreased fecundity | female | RU486 conditional phenotype, non-suppressible by foxo^Δ94

(Slack et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by Akt1[+]/Akt^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by Pten^unspecified/Pten[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by Rheb^unspecified/Rheb[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by Tsc1[+]/Tsc1^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by eIF3h^k09003/eIF-3p40[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by eIF4E1⁰⁷²³⁸/eIF-4E[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by eIF-4a[+]/eIF4A^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by foxo[+]/foxo^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has visible phenotype, non-suppressible by Pi3K21B^unspecified/Pi3K21B[+]

(Coelho et al., 2005)

Enhancer of

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 is an enhancer of abnormal size phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell number phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 is an enhancer of decreased cell size phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of increased cell death phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^GMR.PF

(Yang et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL is an enhancer of increased cell death phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, foxo^UAS.cFa

(Junger et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, foxo^EP35-147

(Junger et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Mmus\Foxo1^UAS.cKa, Scer\GAL4^GMR.PF

(Kramer et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Scer\GAL4^GMR.PF, foxo^UAS.cKa

(Kramer et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of visible phenotype of Mmus\Foxo1^AA.UAS, Scer\GAL4^GMR.PF

(Kramer et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ey.PH is an enhancer of abnormal size | adult stage phenotype of Pten^UAS.cHa, Scer\GAL4^ey.PH

(Huang et al., 1999)

Suppressor of

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^hh.PU is a suppressor | partially of increased cell death | third instar larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^hh.PU, rl^GD4697

(Murcia et al., 2019)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^{Act5C.CoinFLP-FRT} is a suppressor | partially | somatic clone of neoplasia | somatic clone | cell non-autonomous | third instar larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^{Act5C.CoinFLP-FRT}, dlg1^GD4689

(Katheder et al., 2017)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^{Act5C.CoinFLP-FRT} is a suppressor | partially | somatic clone of abnormal size | somatic clone | cell non-autonomous | third instar larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^{Act5C.CoinFLP-FRT}, dlg1^GD4689

(Katheder et al., 2017)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ppk.PG is a suppressor | partially of abnormal neuroanatomy | pupal stage phenotype of Cul1^GD9650, Scer\GAL4^ppk.PG

(Wong et al., 2013)

Pi3K92E^{D954A.UAS.Tag:MYC}/Scer\GAL4^Gli-rL82 is a suppressor of abnormal neuroanatomy | third instar larval stage phenotype of egh^62d18

(Dahlgaard et al., 2012)

Pi3K92E^{D954A.UAS.Tag:MYC}/Scer\GAL4^amn-c651 is a suppressor of visible phenotype of CycE^JP

(Lin et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of visible phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY3207

(Raisin et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of visible phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY1678

(Raisin et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of visible phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY789

(Raisin et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of visible phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY1079

(Raisin et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}/Scer\GAL4^Bx-MS1096 is a suppressor of increased cell size | somatic clone phenotype of Pten^dj189

(Gao et al., 2000)

NOT Suppressor of

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}/Scer\GAL4^arm.PU is a non-suppressor of decreased fecundity | female phenotype of Ptp61F^Δ

(Buszard et al., 2013)

Pi3K92E^{D954A.UAS.Tag:MYC}/Scer\GAL4^da.Switch.PT is a non-suppressor of viable | RU486 conditional phenotype of foxo^Δ94

(Slack et al., 2011)

Phenotype Manifest In

Enhanced by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-2g[+]/ebi^2g1

(Marygold et al., 2011, Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-2g[+]/ebi^2g2

(Marygold et al., 2011, Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi^E90/ebi[+]

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi[+]/ebi^CC3

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi[+]/ebi^CCS-8

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi[+]/ebi^E4

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi^Δ1/ebi[+]

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi[+]/ebi^W418X

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi[+]/ebi^k16213

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi[+]/ebi^WKS-24

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ebi[+]/ebi^P7

(Marygold et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 has wing phenotype, enhanceable by hppy^UAS.cMa, Scer\GAL4^nub-AC-62

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by pix^3c3/pix[+]

(Coelho et al., 2005, Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by pix^3c2/pix[+]

(Coelho et al., 2005, Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Tor[+]/mTor^2L19

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by chico^flp147E

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by lep^3c5/lep[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by lep^3c6/lep[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ncm^2a2/ncm[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by ncm[+]/ncm^SH0931

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by oho23B[+]/RpS21⁰³⁵⁷⁵

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by prp8[+]/Prp8^2e1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Prp8^2e2/prp8[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)A209/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)C246/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)G4e^LH24i^R/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)HA85/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)HF396/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)JA26/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)JA27/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)KA14/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)KA7/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)N-8/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)N105/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)N19/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)dm75e19/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Df(1)sd72b/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-2c[+]/E-2c^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-2fa[+]/E-2fa²

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-2fb³/E-2fb[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-3c1[+]/E-3c1¹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-3c4[+]/E-3c4⁴

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by E-3c7⁷/E-3c7[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by InR³³⁹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpL38[+]/RpL38^2b1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpL38[+]/RpL38^2b2

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpL5^2d1/RpL5[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpL5^2d2/RpL5[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpLP1[+]/RpLP1^beo

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpS13¹/RpS13[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpS17⁶/RpS17[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpS26⁰⁴⁵⁵³/RpS26[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpS26^KG00230/RpS26[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpS3[+]/RpS3¹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpS3A[+]/RpS3A^57g

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by RpS5a[+]/RpS5a¹

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, enhanceable by Tor[+]/mTor^ΔP

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF has eye phenotype, enhanceable by Hsap\FOXO3^UAS.cFa, Scer\GAL4^GMR.PF

(Junger et al., 2003)

NOT Enhanced by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by Akt1[+]/Akt^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by Pi3K21B^unspecified/Pi3K21B[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by Pten^unspecified/Pten[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by Rheb^unspecified/Rheb[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by Tsc1[+]/Tsc1^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by eIF3h^k09003/eIF-3p40[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by eIF4E1⁰⁷²³⁸/eIF-4E[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by eIF-4a[+]/eIF4A^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-enhanceable by foxo[+]/foxo^unspecified

(Coelho et al., 2005)

Suppressed by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU has larval brain | third instar larval stage phenotype, suppressible | partially by Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU has larval glial cell | third instar larval stage | decreased number phenotype, suppressible | partially by Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ppl.PP has embryonic/larval salivary gland phenotype, suppressible by Cds^EY08412, Scer\GAL4^ppl.PP

(Liu et al., 2014)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible by Df(1)BA1/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible by ap[+]/ap^2a1

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible by ap^2a2/ap[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible | partially by Df(2R)nap1/+

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF, foxo^GS9928 has ommatidium phenotype, suppressible by Akt^UAS.cSa, Scer\GAL4^GMR.PF

(Goberdhan et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ptc-559.1 has first posterior wing cell phenotype, suppressible by Pdk1^EP3553, Scer\GAL4^ptc-559.1

(Cho et al., 2001)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ey.PH has eye phenotype, suppressible by Akt^hs.PS, Scer\GAL4^ey.PH

(Scanga et al., 2000)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible | partially by Pten¹

(Goberdhan et al., 1999)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, suppressible | partially by Df(2L)flp170B

(Goberdhan et al., 1999)

NOT suppressed by

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by Pi3K21B^unspecified/Pi3K21B[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by Pten^unspecified/Pten[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by Rheb^unspecified/Rheb[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by Tsc1[+]/Tsc1^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by eIF3h^k09003/eIF-3p40[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by eIF4E1⁰⁷²³⁸/eIF-4E[+]

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by eIF-4a[+]/eIF4A^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by foxo[+]/foxo^unspecified

(Coelho et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing phenotype, non-suppressible by Akt1[+]/Akt^unspecified

(Coelho et al., 2005)

Enhancer of

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^nub-AC-62 is an enhancer of wing phenotype of Scer\GAL4^nub-AC-62, hppy^UAS.cMa

(Resnik-Docampo and de Celis, 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, foxo^GS9928

(Goberdhan et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Ddc.PL is an enhancer of dopaminergic neuron phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^Ddc.PL

(Yang et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of eye photoreceptor cell phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^GMR.PF

(Yang et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^GMR.PF

(Yang et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of ommatidium phenotype of DJ-1α^RNAi.UAS, Scer\GAL4^GMR.PF

(Yang et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, foxo^UAS.cFa

(Junger et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, foxo^UAS.cFa

(Junger et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, foxo^EP35-147

(Junger et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of ommatidium phenotype of Scer\GAL4^GMR.PF, foxo^EP35-147

(Junger et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Mmus\Foxo1^UAS.cKa, Scer\GAL4^GMR.PF

(Kramer et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Scer\GAL4^GMR.PF, foxo^UAS.cKa

(Kramer et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is an enhancer of eye phenotype of Mmus\Foxo1^AA.UAS, Scer\GAL4^GMR.PF

(Kramer et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is an enhancer of wing phenotype of Pten^UAS.cGb, Scer\GAL4^Bx-MS1096

(Gao et al., 2000)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ey.PH is an enhancer of eye phenotype of Pten^UAS.cHa, Scer\GAL4^ey.PH

(Huang et al., 1999)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ey.PH is an enhancer of ommatidium phenotype of Pten^UAS.cHa, Scer\GAL4^ey.PH

(Huang et al., 1999)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ey.PH is an enhancer of eye disc phenotype of Pten^UAS.cHa, Scer\GAL4^ey.PH

(Huang et al., 1999)

Suppressor of

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^hh.PU is a suppressor | partially of wing disc | third instar larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^hh.PU, rl^GD4697

(Murcia et al., 2019)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^ppk.PG is a suppressor | partially of larval dorsal multidendritic neuron ddaC | pupal stage phenotype of Cul1^GD9650, Scer\GAL4^ppk.PG

(Wong et al., 2013)

Pi3K92E^{D954A.UAS.Tag:MYC}/Scer\GAL4^Gli-rL82 is a suppressor of larval peripheral nervous system | third instar larval stage phenotype of egh^62d18

(Dahlgaard et al., 2012)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Toll-6-D42 is a suppressor of bouton phenotype of CaMKII^T287D.UAS, Scer\GAL4^Toll-6-D42

(Chun-Jen Lin et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}/Scer\GAL4^amn-c651 is a suppressor of eye phenotype of CycE^JP

(Lin et al., 2011)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of wing phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY3207

(Raisin et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of wing phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY1678

(Raisin et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of wing phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY789

(Raisin et al., 2003)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 is a suppressor of wing phenotype of Scer\GAL4^Bx-MS1096, mir-ban^UY1079

(Raisin et al., 2003)

NOT Suppressor of

Statement

Reference

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^{Act5C.CoinFLP-FRT} is a non-suppressor | cell non-autonomous | somatic clone of autophagosome | somatic clone | cell non-autonomous | third instar larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^{Act5C.CoinFLP-FRT}, dlg1^GD4689

(Katheder et al., 2017)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^{Act5C.CoinFLP-FRT} is a non-suppressor | cell non-autonomous | somatic clone of eye-antennal disc | somatic clone | cell non-autonomous | third instar larval stage phenotype of Ras85D^V12.UAS, Scer\GAL4^{Act5C.CoinFLP-FRT}, dlg1^GD4689

(Katheder et al., 2017)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is a non-suppressor of eye photoreceptor cell phenotype of Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF

(Yang et al., 2005)

Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^GMR.PF is a non-suppressor of eye phenotype of Hsap\MAPT^V337M.UAS, Scer\GAL4^GMR.PF

(Yang et al., 2005)

Other

Statement

Reference

E-2c^unspecified, Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096 has wing vein phenotype

(Coelho et al., 2005)

Additional Comments

Genetic Interactions

Statement

Reference

Third instar larval eye-antennal imaginal disc clones co-expressing dlg1^GD4689 and Ras85D^V12.Scer\UAS under the control of Scer\GAL4^{Act5C.CoinFLP-FRT}, in combination with Dicer-2 for efficient RNAi, form invasive tumors and induce autophagosomes (assessed by a Atg8a fluorescence reporter) in a cell non-autonomous manner in neighboring disc tissue, which are suppressed and not suppressed, respectively, by the additional clonal co-expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}.

(Katheder et al., 2017)

Overexpression of CdsA^EY08412 partially, but significantly, rescues the small cell size phenotype found in flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} (when both are expressed in the salivary gland and fat body, under the control of Scer\GAL4^ppl.PP). Moreover, the salivary gland ectopic lipid storage phenotype found in Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}-expressing flies can be fully suppressed by CdsA^EY08412 overexpression.

(Liu et al., 2014)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^arm.PU fails to rescue the reduced fecundity of Ptp61F^Δ females.

(Buszard et al., 2013)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} dramatically suppresses the dendrite pruning defects seen in ddaC neurons expressing lin19^GD9650 under the control of Scer\GAL4^ppk.PG at 16 hours after pupariation. No difference is seen in white prepupae.

(Wong et al., 2013)

Subperineurial expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Gli-rL82 strongly suppresses the egh^62d18 nerve phenotype.

(Dahlgaard et al., 2012)

In larvae co-expressing CaMKII^{T287D.Scer\UAS} and Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^D42, the CaMKII^{T287D.Scer\UAS}-dependent increase in bouton number is completely suppressed and is decreased to a value indistinguishable from that conferred by expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} alone.

(Chun-Jen Lin et al., 2011)

Expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^amn-c651 suppresses the CycE^JP small eye phenotype.

(Lin et al., 2011)

Heterozygosity for ebi^2g2, ebi^E90, ebi^CC3, ebi^2g1, ebi^CCS-8, ebi^E4, ebi^Δ1, ebi^W418X, ebi^k16213, ebi^WKS-24 or ebi^P7 enhances the small wing phenotype induced by Scer\GAL4^Bx-MS1096-mediated expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}.

(Marygold et al., 2011)

Co-expression of hppy^Scer\UAS.cMa and Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} using Scer\GAL4^nub-AC-62 results in a strong synergistic phenotype of reduced wing size and reduced cell size and number.

(Resnik-Docampo and de Celis, 2011)

A foxo^Δ94 mutant background suppresses the extension in lifespan seen upon RU486-induced expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.Switch.PT.

Adult onset ubiquitous expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of the RU486-inducible Scer\GAL4^da.Switch.PT has no effect on the viability of foxo^Δ94 flies.

A foxo^Δ94 mutant background does not affect the decrease in egg-laying found upon adult-specific ubiquitous expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.Switch.PT.

foxo^Δ94 mutant flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.Switch.PT all survive for longer on food supplemented with 20mM paraquat compared to controls (but shorter compared to expression in a wild-type background).

A foxo^Δ94 background suppresses the DTT resistance seen in flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.Switch.PT.

foxo^Δ94 mutant flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^da.G32 all survive for longer on food supplemented with 20mM paraquat compared to controls (but shorter compared to expression in a wild-type background).

(Slack et al., 2011)

The small wing phenotype of Scer\GAL4^Bx-MS1096>Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} flies is enhanced by pix^3c2/+ and pix^3c3/+.

(Coelho et al., 2005)

Flies expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^Bx-MS1096 and carrying E-2c^unspecified have ectopic wing vein tissue.

(Coelho et al., 2005)

The ommatidial loss phenotype of foxo^GS9928 mutants is strongly enhanced by co-expressing Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF.

(Goberdhan et al., 2005)

Coexpression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} with DJ-1α^{dsRNA.Scer\UAS}, under the control of Scer\GAL4^GMR.PF enhances the DJ-1α^{dsRNA.Scer\UAS}-induced eye phenotype.

(Yang et al., 2005)

Co-expression of foxo^Scer\UAS.cKa and Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF almost completely obliterates the eyes.

(Kramer et al., 2003)

The downward curvature of the wing blade caused by expression of ban^UY3207, ban^UY1678, ban^UY789 or ban^UY1079 under the control of Scer\GAL4^Bx-MS1096 is suppressed by co-expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}.

(Raisin et al., 2003)

Ectopic expression of Akt1^hs.PS suppresses the small eye phenotype resulting from the expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} driven by Scer\GAL4^ey.PH.

(Scanga et al., 2000)

The reduction in wing size seen when Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} is driven by Scer\GAL4^Bx-MS1096 is partially suppressed by Pten¹ or Df(2L)flp170B.

(Goberdhan et al., 1999)

Enhances the eye phenotype caused by Pten^Scer\UAS.cHa, when co-expressed using Scer\GAL4^ey.PH.

(Huang et al., 1999)

Xenogenetic Interactions

Statement

Reference

Coexpression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} with Hsap\MAPT^{V337M.Scer\UAS}, under the control of Scer\GAL4^GMR.PF has no effect on the Hsap\MAPT^{V337M.Scer\UAS}-induced toxicity in the eye.

(Yang et al., 2005)

Co-expression of Mmus\Foxo1^AA.Scer\UAS and Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC} under the control of Scer\GAL4^GMR.PF almost completely obliterates the eyes.

(Kramer et al., 2003)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

25918

y¹ w^*; P{Dp110^D954A}2

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (9)

Reported As

Symbol Synonym

Dp110^D954A

(Azuma et al., 2021, Resino and Garcia-Bellido, 2004, Raisin et al., 2003, Miron et al., 2001, Bohni et al., 1999)

Dp110^DN

(Romero-Pozuelo et al., 2017, Huang et al., 1999)

PI3K^D954A

(Caldwell et al., 2005)

PI3K^DN

(Marygold et al., 2004)

Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}

Pi3K92E^{D954A.UAS.T:Myc}

Pi3K92E^{D954A.UAS.Tag:MYC}

Pi3K92E[D954A]

(Lavery and Stern, 2006)

UAS-Dp110DN

(Junger et al., 2003)

Name Synonyms

Secondary FlyBase IDs

References (79)

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