FlyBase Allele Report: Dmel\Wdr62[UAS.Tag:HA]

FB2026_02 , released June 18, 2026

FB2026_02 , released June 18, 2026

Allele: Dmel\Wdr62^UAS.Tag:HA

General Information

Symbol

Dmel\Wdr62^UAS.Tag:HA

Species

D. melanogaster

Name

FlyBase ID

FBal0361084

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

P{UAS-Wdr62.HA}

Key Links

Transgenic product class

(Shohayeb et al., 2020)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

(Shohayeb et al., 2020)

Mutagen

in vitro construct

(Shohayeb et al., 2020)

Progenitor genotype

Carried in construct

P{UAS-Wdr62.HA}

Cytology

Description

UAS regulatory sequences drive expression of Wdr62 that is tagged with Tag:HA.

(Shohayeb et al., 2020)

Allele components

Component

Use(s)

Regulatory region(s)

binary expression system - regulatory region

Encoded product / tool

Tagged with

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 1 )

Disease

Evidence

References

model of high grade glioma

CEA

(Shohayeb et al., 2020)

Modifiers Based on Experimental Evidence ( 1 )

Disease

Interaction

References

model of high grade glioma

is ameliorated by Akt^KK100495

(Shohayeb et al., 2020)

is ameliorated by Myc^GD1419

(Shohayeb et al., 2020)

is ameliorated by Pi3K92E^{D954A.UAS.Tag:MYC}

(Shohayeb et al., 2020)

is ameliorated by aurA^KK100143

(Shohayeb et al., 2020)

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

Expression of Wdr62^UAS.Tag:HA under the control of Scer\GAL4^repo.PU leads to an increase in the brain volume, the percentage of glial cells in mitosis, the glial cell size, the glial nucleolus size and the percentage of neuroblasts in mitosis. It also leads to a decrease in the proportion of G1 phase glia but an increase in the number of glial cells in G2/M in third instar larvae.

Expression of Wdr62^UAS.Tag:HA under the control of Scer\GAL4^insc.PU leads to an increase in the brain volume in third instar larvae.

(Shohayeb et al., 2020)

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has increased size | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has increased cell number | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has increased occurrence of cell division | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has abnormal mitotic cell cycle | third instar larval stage phenotype, suppressible | partially by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has increased cell size | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

NOT Enhancer of

Statement

Reference

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-enhancer of decreased size | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-enhancer of decreased cell size | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Suppressor of

Statement

Reference

Wdr62^UAS.Tag:HA/Scer\GAL4^repo.PU is a suppressor of decreased cell number | third instar larval stage phenotype of Scer\GAL4^repo.PU, aurA^KK100143

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA/Scer\GAL4^repo.PU is a suppressor of increased occurrence of cell division | third instar larval stage phenotype of Scer\GAL4^repo.PU, aurA^KK100143

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA/Scer\GAL4^repo.PU is a suppressor | partially of abnormal mitotic cell cycle | third instar larval stage phenotype of Scer\GAL4^repo.PU, aurA^KK100143

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of decreased size | third instar larval stage phenotype of Akt^KK100495, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of decreased cell number | third instar larval stage phenotype of Akt^KK100495, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of decreased cell size | third instar larval stage phenotype of Akt^KK100495, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of decreased size | third instar larval stage phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of decreased cell number | third instar larval stage phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA/Scer\GAL4^repo.PU is a suppressor of decreased size | third instar larval stage phenotype of Scer\GAL4^repo.PU, aurA^KK100143

(Shohayeb et al., 2020)

NOT Suppressor of

Statement

Reference

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-suppressor of decreased size | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-suppressor of decreased cell size | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has larval brain | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has larval glial cell | increased number | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has larval neuroblast | increased number | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

Scer\GAL4^repo.PU, Wdr62^UAS.Tag:HA has nucleolus | third instar larval stage phenotype, suppressible by Scer\GAL4^repo.PU/aurA^KK100143

(Shohayeb et al., 2020)

NOT Enhancer of

Statement

Reference

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-enhancer of larval brain | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-enhancer of nucleolus | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-enhancer of larval neuroblast | third instar larval stage | decreased number phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-enhancer of larval glial cell | third instar larval stage | decreased number phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Suppressor of

Statement

Reference

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of larval brain | third instar larval stage phenotype of Akt^KK100495, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of larval glial cell | third instar larval stage | decreased number phenotype of Akt^KK100495, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of nucleolus | third instar larval stage phenotype of Akt^KK100495, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of larval brain | third instar larval stage phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a suppressor | partially of larval glial cell | third instar larval stage | decreased number phenotype of Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA/Scer\GAL4^repo.PU is a suppressor of larval brain | third instar larval stage phenotype of Scer\GAL4^repo.PU, aurA^KK100143

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA/Scer\GAL4^repo.PU is a suppressor of larval glial cell | third instar larval stage | decreased number phenotype of Scer\GAL4^repo.PU, aurA^KK100143

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA/Scer\GAL4^repo.PU is a suppressor of larval neuroblast | third instar larval stage | decreased number phenotype of Scer\GAL4^repo.PU, aurA^KK100143

(Shohayeb et al., 2020)

NOT Suppressor of

Statement

Reference

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-suppressor of larval brain | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-suppressor of nucleolus | third instar larval stage phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-suppressor of larval neuroblast | third instar larval stage | decreased number phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Wdr62^UAS.Tag:HA, Scer\GAL4^repo.PU is a non-suppressor of larval glial cell | third instar larval stage | decreased number phenotype of Myc^GD1419, Scer\GAL4^repo.PU

(Shohayeb et al., 2020)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Wdr62^UAS.Tag:HA

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections