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General Information
Symbol
Dmel\ebiE90
Species
D. melanogaster
Name
FlyBase ID
FBal0096972
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Nature of the Allele
Mutations Mapped to the Genome
 
Type
Location
Additional Notes
References
point mutation
Nucleotide change:

G417060A

Amino acid change:

C510Y | ebi-PA

Associated Sequence Data
DNA sequence
Protein sequence
 
 
Progenitor genotype
Cytology
Nature of the lesion
Statement
Reference

Amino acid replacement: C510Y. Nucleotide substitution: the TGC codon encoding C510 is changed to TAC.

Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

ebiP7/ebiE90 escaper flies are more sensitive to paraquat treatment than controls.

No or very few ebiE90 clones survive to late third instar stage when induced at 48 hours after egg deposition (AED), and survival is not improved by inducing clones in a Minute/+ background. Clones induced at 72 hours AED do survive, but are very small.

ebiP7/ebiE90 flies are viable and show phenotypes similar to weak loss of function Egfr alleles including partial female sterility resulting from partially ventralized eggs, wing vein defects, short bristles and rough eyes.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Suppressed by
Statement
Reference
Enhancer of
Statement
Reference
Phenotype Manifest In
Enhancer of
Statement
Reference

ebiE90/ebi[+] is an enhancer of wing vein phenotype of Scer\GAL4Bx-MS1096, aosUAS.cMa

ebiE90/ebi[+] is an enhancer of wing margin phenotype of sdETX4

ebiE90/ebi[+] is an enhancer of ommatidium phenotype of SosJC2, sev6

ebiE90/ebi[+] is an enhancer of photoreceptor cell R7 phenotype of SosJC2, sev6

ebiE90/ebi[+] is an enhancer of ommatidium phenotype of SosJC2/Sos[+], sev6

ebiE90/ebi[+] is an enhancer of photoreceptor cell R7 phenotype of SosJC2/Sos[+], sev6

ebiE90 is an enhancer of eye phenotype of rux3

Suppressor of
Statement
Reference

ebiE90 is a suppressor of sex comb phenotype of Pc1

ebiE90 is a suppressor of metathoracic leg phenotype of Pc1

ebiE90 is a suppressor of mesothoracic leg phenotype of Pc1

ebiE90 is a suppressor of eye phenotype of Egfr::tort4021E.hs.sev

NOT Suppressor of
Statement
Reference

ebiE90 is a non-suppressor of eye phenotype of sev::tor13D.hs.sev

Additional Comments
Genetic Interactions
Statement
Reference

Heterozygosity for ebiE90 enhances the small wing phenotype induced by Scer\GAL4Bx-MS1096-mediated expression of Pi3K92ED954A.Scer\UAS.T:Hsap\MYC.

Heterozygosity for ebiE90 enhances the small wing and wing vein loss phenotypes induced by Scer\GAL4Bx-MS1096-mediated expression of aosScer\UAS.cMa.

Heterozygosity for ebiE90 enhances the notched wing margin phenotype seen in sdETX4 hemizygous males.

In sev6 hemizygotes that are also heterozygous for SosJC2, 14.7% of ommatidia contain R7 cells. This phenotype is dominantly enhanced by ebiE90.

Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Rescued by
Comments

ebi+t7.5 rescues the homozygous lethality of ebiE90.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
Comments
Comments

Strong allele.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Name Synonyms
Secondary FlyBase IDs
    References (5)