FB2026_02 , released June 18, 2026
Allele: Dmel\ebiΔ1
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General Information
Symbol
Dmel\ebiΔ1
Species
D. melanogaster
Name
FlyBase ID
FBal0265167
Feature type
allele
Associated gene
Dmel\ebi
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description

    ebiΔ1 is an 8bp deletion within the 10bp sequence GCGTAGGAGC

    (Marygold S.J., 2013.9.6)

    The mutant chromosome retained a 'GC' dinucleotide in this position, so it is not possible to distinguish between:

    (Marygold S.J., 2013.9.6)

    - del of first 8bp: GCGTAGGA

    (Marygold S.J., 2013.9.6)

    - del last 8bp: GTAGGAGC

    (Marygold S.J., 2013.9.6)

    - del of middle 8bp: CGTAGGAG

    (Marygold S.J., 2013.9.6)

    8 bp deletion, resulting in frame-shift from codon 294 and the introduction of a STOP codon at position 334 (prior to the WD repeat-encoding region).

    (Marygold et al., 2011)
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    delins
    2L:416,335..416,342 [+]
    Comment:

    8 bp deletion within the 10 bp sequence GCGTAGGAGC, resulting in frame-shift from codon 294 and the introduction of a STOP codon at position 334. The mutant chromosome retained a GC dinucleotide at the site, making it impossible to tell exactly which bases were deleted.

    Inserted_sequence:

    GC

    (Marygold S.J., 2013.9.6, Marygold et al., 2011)
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        ebiP7/ebiΔ1 wings are 84% the size of control wings. Wing cell size is unaffected - the wing size reduction is the result of fewer cells. Gross defects in wing patterning are not apparent. There is no significant decrease in the size of other organs or the whole organism.

        (Marygold et al., 2011)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Enhancer of
        Statement
        Reference

        ebiΔ1/ebi[+] is an enhancer of abnormal size phenotype of Pi3K92ED954A.UAS.Tag:MYC, Scer\GAL4Bx-MS1096

        (Marygold et al., 2011)

        ebiΔ1/ebi[+] is an enhancer of abnormal size phenotype of Scer\GAL4Bx-MS1096, aosUAS.cMa

        (Marygold et al., 2011)
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        ebiΔ1/ebi[+] is an enhancer of wing phenotype of Pi3K92ED954A.UAS.Tag:MYC, Scer\GAL4Bx-MS1096

        (Marygold et al., 2011)

        ebiΔ1/ebi[+] is an enhancer of wing vein phenotype of Scer\GAL4Bx-MS1096, aosUAS.cMa

        (Marygold et al., 2011)

        ebiΔ1/ebi[+] is an enhancer of wing margin phenotype of sdETX4

        (Marygold et al., 2011)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        Heterozygosity for ebiΔ1 enhances the small wing phenotype induced by Scer\GAL4Bx-MS1096-mediated expression of Pi3K92ED954A.Scer\UAS.T:Hsap\MYC.

        Heterozygosity for ebiΔ1 enhances the small wing and wing vein loss phenotypes induced by Scer\GAL4Bx-MS1096-mediated expression of aosScer\UAS.cMa.

        Heterozygosity for ebiΔ1 enhances the notched wing margin phenotype seen in sdETX4 hemizygous males.

        (Marygold et al., 2011)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer
        Comments
        Comments

        ebiΔ1 is similar, but not identical, to the ebiCC4 mutation described in FBrf0131258. ebiΔ1 was obtained from P. Heitzler, who is an author of FBrf0131258, raising the possibility that ebiΔ1 and ebiCC4 are in fact the same allele, but that different labs produced conflicting sequencing results/analysis.

        (Marygold et al., 2011)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (2)
        Reported As
        Symbol Synonym
        ebidelta1
        (Marygold et al., 2011)
        ebiΔ1
        (Marygold et al., 2011)
        Name Synonyms
        Secondary FlyBase IDs
          References (2)