FlyBase Allele Report: Dmel\mir-ban[UY3207]

General Information

Symbol

Dmel\mir-ban^UY3207

Species

D. melanogaster

Name

FlyBase ID

FBal0152107

Feature type

allele

Associated gene

Dmel\mir-ban

Associated Insertion(s)

P{Mae-UAS.6.11}mir-ban^UY3207

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Raisin et al., 2003)

Progenitor genotype

Associated Insertion(s)

P{Mae-UAS.6.11}mir-ban^UY3207

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{Mae-UAS.6.11}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

decreased body size

(Raisin et al., 2003)

decreased body size (with Df(3L)emc)

(Raisin et al., 2003)

decreased body size (with Df(3L)mir-ban^Δ1)

(Raisin et al., 2003)

decreased body size (with mir-ban^EP3622)

(Raisin et al., 2003)

decreased cell number

(Raisin et al., 2003)

decreased cell number (with Df(3L)mir-ban^Δ1)

(Raisin et al., 2003)

decreased cell number (with mir-ban^EP3622)

(Raisin et al., 2003)

visible, with Scer\GAL4^Bx-MS1096

(Raisin et al., 2003)

visible, with Scer\GAL4^en-e16E

(Raisin et al., 2003)

visible, with Scer\GAL4^GMR.PF

(Raisin et al., 2003)

Phenotype Manifest In

eye, with Scer\GAL4^GMR.PF

(Raisin et al., 2003)

ommatidium, with Scer\GAL4^GMR.PF

(Raisin et al., 2003)

wing

(Raisin et al., 2003)

wing, with Scer\GAL4^Bx-MS1096

(Raisin et al., 2003)

wing, with Scer\GAL4^en-e16E

(Raisin et al., 2003)

wing (with Df(3L)emc)

(Raisin et al., 2003)

wing (with Df(3L)mir-ban^Δ1)

(Raisin et al., 2003)

wing (with mir-ban^EP3622)

(Raisin et al., 2003)

Detailed Description

Statement

Reference

Expression of ban^UY3207 under the control of Scer\GAL4^Bx-MS1096 results in a downward curvature of the wing. Expression of ban^UY3207 under the control of Scer\GAL4^en-e16E results in an overgrowth phenotype in the posterior compartment of the wing. Expression of ban^UY3207 under the control of Scer\GAL4^GMR.PF results in enlargement of overall eye size and an increase in the size of individual ommatidia. The body mass of homozygotes is 90% that of control flies. The wing blade surface area is 94.4% that of controls. Cell size in the wing blade is 99.2% of controls and cell number in the wing blade is 94.5% that of controls. The body mass of ban^UY3207/Df(3L)emc flies is 73% that of control flies. The wing blade surface area is 84.9% that of controls. The body mass of ban^UY3207/Df(3L)ban^Δ1 flies is 82% that of control flies. The wing blade surface area is 90.3% that of controls. Cell size in the wing blade is 100.2% of controls and cell number in the wing blade is 89.9% that of controls. The body mass of ban^EP3622/ban^UY3207 flies is 84% that of control flies. The wing blade surface area is 92.6% that of controls. Cell size in the wing blade is 99.3% of controls and cell number in the wing blade is 92.8% that of controls. Wing disc cells expressing ban^UY3207 under the control of Scer\GAL4^Act5C.PP in clones are not different in size to control wing disc cells. Cell doubling time is reduced by 15% as compared to control clones.

(Raisin et al., 2003)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, mir-ban^UY3207 has visible phenotype, suppressible by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096

(Raisin et al., 2003)

Phenotype Manifest In

Suppressed by

Statement

Reference

Scer\GAL4^Bx-MS1096, mir-ban^UY3207 has wing phenotype, suppressible by Pi3K92E^{D954A.UAS.Tag:MYC}, Scer\GAL4^Bx-MS1096

(Raisin et al., 2003)

Additional Comments

Genetic Interactions

Statement

Reference

The downward curvature of the wing blade caused by expression of ban^UY3207 under the control of Scer\GAL4^Bx-MS1096 is suppressed by co-expression of Pi3K92E^{D954A.Scer\UAS.T:Hsap\MYC}.

(Raisin et al., 2003)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Partially rescues

Scer\GAL4^arm.PS/mir-ban^UY3207 partially rescues Df(3L)emc/+

(Raisin et al., 2003)

Comments

The reduction in body size seen in Df(3L)emc/+ flies is partly rescued by expression of ban^UY3207 under the control of Scer\GAL4^arm.PS.

(Raisin et al., 2003)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

ban^UY3207

mir-ban^UY3207

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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