FB2026_02 , released June 18, 2026
Allele: Dmel\Abp1UAS.cKa
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General Information
Symbol
Dmel\Abp1UAS.cKa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct of Koch
FlyBase ID
FBal0284220
Feature type
allele
Associated gene
Dmel\Abp1
Associated Insertion(s)
Carried in Construct
P{UAS-Abp1.K}
Key Links
Transgenic product class
wild_type
(Koch et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Koch et al., 2012)
Mutagen
in vitro construct
(Koch et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-Abp1.K}
Cytology
Description

UAS regulatory sequences drive expression of Abp1.

(Koch et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Abp1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4VGlut1-OK371/Abp1UAS.cKa rescues Df(3L)Exel6119/Abp1KO

      (Koch et al., 2014)
      Partially rescues

      Abp1UAS.cKa/Scer\GAL4C57 partially rescues Df(3L)Exel6119/Abp1KO

      (Koch et al., 2014)

      Scer\GAL4sca.PU/Abp1UAS.cKa partially rescues Df(3L)Exel6119/Abp1KO

      (Koch et al., 2012)
      Comments

      The reduction in the number of type Ib boutons which is seen at the neuromuscular junction (NMJ) in Abp1KO/Df(3L)Exel6119 third instar larvae is rescued by expression of Abp1Scer\UAS.cKa under the control of Scer\GAL4VGlut-OK371 (in motorneurons), but not under the control of Scer\GAL4C57 (in muscles). The reduction in the number of axonal branch points per NMJ which is seen in Abp1KO/Df(3L)Exel6119 third instar larvae is rescued by expression of Abp1Scer\UAS.cKa under the control of either Scer\GAL4VGlut-OK371 or Scer\GAL4C57.

      (Koch et al., 2014)

      The extra longitudinal ridge phenotype seen in macrochaetae of Abp1KO/Df(3L)Exel6119 flies is partially rescued by expression of Abp1Scer\UAS.cKa under the control of Scer\GAL4sca.PU.

      (Koch et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Abp1Scer\UAS.cKa
      Abp1UAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct of Koch
      Secondary FlyBase IDs
        References (2)