FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Nf1UAS.CFP
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General Information
Symbol
Dmel\Nf1UAS.CFP
Species
D. melanogaster
Name
FlyBase ID
FBal0287820
Feature type
allele
Associated gene
Dmel\Nf1
Associated Insertion(s)
Carried in Construct
P{UAS-CFP-Nf1.FL}
Key Links
Transgenic product class
wild_type
(Tsai et al., 2012)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tsai et al., 2012)
Mutagen
in vitro construct
(Tsai et al., 2012)
Progenitor genotype
Carried in construct
P{UAS-CFP-Nf1.FL}
Cytology
Description

UAS regulatory sequences drive expression of full-length Nf1 which is tagged with CFP.

(Tsai et al., 2012)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Nf1
Tagged with
CFP
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Scer\GAL4elav.PU/Nf1UAS.CFP is a suppressor of abnormal neuroanatomy | larval stage phenotype of FakK24/FakN30

      (Tsai et al., 2012)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4elav.PU/Nf1UAS.CFP is a suppressor of NMJ bouton | increased number | larval stage phenotype of FakK24/FakN30

      (Tsai et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of Nf1Scer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4elav.PU rescues the neuromuscular junction overgrowth phenotype seen in FakN30/FakK24 larvae.

      (Tsai et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PU/Nf1UAS.CFP rescues Nf1E2

      (Tsai et al., 2012)
      Fails to rescue

      Scer\GAL4C57/Nf1UAS.CFP fails to rescue Nf1E2

      (Tsai et al., 2012)
      Comments

      Expression of Nf1Scer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4C57 fails to rescue the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae.

      Expression of Nf1Scer\UAS.T:Avic\GFP-CFP under the control of Scer\GAL4elav.PU rescues the neuromuscular junction overgrowth phenotype seen in Nf1E2/Nf1E2 larvae. The increase in EJP amplitude is also largely rescued.

      (Tsai et al., 2012)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Nf1Scer\UAS.T:Avic\GFP-CFP
      Nf1UAS.CFP
      Name Synonyms
      Secondary FlyBase IDs
        References (1)