FlyBase Allele Report: Dmel\DCAF12[Δ51]

FB2026_01 , released March 12, 2026

FB2026_01 , released March 12, 2026

Allele: Dmel\DCAF12^Δ51

General Information

Symbol

Dmel\DCAF12^Δ51

Species

D. melanogaster

Name

FlyBase ID

FBal0408388

Feature type

allele

Associated gene

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - molecular evidence

Mutagen

CRISPR/Cas9

Nature of the Allele

Allele class

amorphic allele - molecular evidence

(Patrón et al., 2019)

Mutagen

(Patrón et al., 2019)

Progenitor genotype

Cytology

Description

2008bp deletion that removes the entire DCAF12 coding region.

(Patrón et al., 2019)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval neuromuscular junction | larval stage

(Patrón et al., 2019)

(Patrón et al., 2019)

neuromuscular junction (with DCAF12^B332)

(Patrón et al., 2019)

neuromuscular junction (with DCAF12^B417)

(Patrón et al., 2019)

(Patrón et al., 2019)

Detailed Description

Statement

Reference

External Data

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

DCAF12^Δ51/Df(3R)Exel7312, Scer\GAL4^Toll-6-D42, VGlut1^UAS.cDa has abnormal neurophysiology phenotype

(Patrón et al., 2019)

DCAF12^Δ51, GluRIIA^SP16 has abnormal neurophysiology phenotype

(Patrón et al., 2019)

DCAF12^B332/DCAF12^Δ51, GluRIIA^SP16 has abnormal neurophysiology | larval stage phenotype

(Patrón et al., 2019)

DCAF12^B332/DCAF12^Δ51, GluRIIA^SP16 has increased mortality during development phenotype

(Patrón et al., 2019)

DCAF12^Δ51, DCAF12^UAS.cPa, GluRIIA^SP16, Scer\GAL4^nSyb.PU has abnormal neurophysiology phenotype

(Patrón et al., 2019)

Phenotype Manifest In

Other

Statement

Reference

DCAF12^Δ51/Df(3R)Exel7312, Scer\GAL4^Toll-6-D42, VGlut1^UAS.cDa has neuromuscular junction phenotype

(Patrón et al., 2019)

DCAF12^Δ51, GluRIIA^SP16 has neuromuscular junction phenotype

(Patrón et al., 2019)

DCAF12^B332/DCAF12^Δ51, GluRIIA^SP16 has embryonic/larval neuromuscular junction | larval stage phenotype

(Patrón et al., 2019)

DCAF12^Δ51, DCAF12^UAS.cPa, GluRIIA^SP16, Scer\GAL4^nSyb.PU has neuromuscular junction phenotype

(Patrón et al., 2019)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Rescued by

DCAF12^Δ51 is rescued by Scer\GAL4^nSyb.PU/DCAF12^UAS.cPa

(Patrón et al., 2019)

Partially rescued by

DCAF12^Δ51 is partially rescued by Scer\GAL4^nSyb.PU/DCAF12^ΔNLS.UAS

(Patrón et al., 2019)

Not rescued by

DCAF12^Δ51 is not rescued by DCAF12^UAS.cPa/Scer\GAL4^C57

(Patrón et al., 2019)

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

DCAF12^Δ51

Δ51

(Patrón et al., 2019)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections