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Citation
Satoh, A.K., Tokunaga, F., Ozaki, K. (1997). Rab proteins of Drosophila melanogaster: Novel members of the Rab-protein family.  FEBS Lett. 404(1): 65--69.
FlyBase ID
FBrf0093208
Publication Type
Research paper
Abstract

From a Drosophila head cDNA library, we isolated 9 cDNA clones, each of which encodes a different member of Rab-protein family. Seven of them (DRabs) have more than 80% amino acid identity to the corresponding members of mammalian Rab proteins. The other two proteins (DRabRP3 and 4) show low sequence similarity to any of the known Rab proteins. However, both contain all amino acids conserved in known Rabs. In addition, DRabRP4 has strong GTP-binding activity, when synthesized in E. coli cells. These results indicate that DRabRPs are novel members of the Rab-protein family. Molecular phylogenetic analysis also supported this conclusion.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    FEBS Lett.
    Title
    FEBS Letters
    Publication Year
    1968-
    ISBN/ISSN
    0014-5793
    Data From Reference
    Genes (12)