Dcp1, caspase, caspase-1
Gene model reviewed during 5.52
There is only one protein coding transcript and one polypeptide associated with this gene
323 (aa); 22 <&> 13 (kD observed)
Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed by a 22 kDa (p22) and a 13 kDa (p13) subunit.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Dcp-1 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Dcp-1 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: Dcp-1 CG5370
Dcp-1 is a positive regulator of starvation-induced autophagic flux during oogenesis.
Dcp-1 controls autophagic flux by a mechanism involving the regulation of the mitochondrial network and maintenance of ATP levels.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.