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General Information
Name
Negative Regulators of Toll-NF-κB Signaling Pathway
Species
D. melanogaster
Symbol
TL-NFN
FlyBase ID
FBgg0001053
Date last reviewed
2020-01-06
Number of members
10
Description
Description

In Drosophila, the canonical Toll signaling pathway is initiated by the binding of a spatzle ligand to Toll (Tl) or a Toll-like receptor leading to the nuclear localization of the NF-κB (dl or Dif) transcription factor. Negative regulators of Toll-NF-κB Signaling lead to the increased cytosolic retention of the NF-κB proteins dl or Dif and/or repression of target gene transcription. (Adapted from FBrf0091014 and FBrf0223077).

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Members (10)
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Synonyms and Secondary IDs
Synonym(s)
TL-NFN
Negative Regulators of Toll-NF-KappaB Signaling Pathway
Negative Regulators of Toll-NF-κB Signaling Pathway
Secondary FlyBase ID(s)
References (18)