FB2026_02 , released June 18, 2026
FB2026_02 , released June 18, 2026
Aberration: Dmel\Df(2R)bw5
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General Information
Symbol
Df(2R)bw5
Species
D. melanogaster
Name
Deficiency (2R) brown
FlyBase ID
FBab0002071
Feature type
chromosomal_deletion
Also Known As
Df(2R)bw5
Computed Breakpoints include

59E1;[>59F6]

Features within 59E1--59F6
Sequence coordinates
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
spontaneous
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Gellon et al., 1997, Song et al., 1997, Harbecke and Lengyel, 1995, Pauli et al., 1995, Dreesen et al., 1988)
Breakpoints

59E1-59E2;59F1

(Dreesen et al., 1988)

59D10-59E1;59E4-59F1

(Gellon et al., 1997, Song et al., 1997, Fryxell and Wood, 1995, Harbecke and Lengyel, 1995, Pauli et al., 1995)
Causes alleles
bw5
(Henikoff et al., 1995)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 << bw << egl << bk2

Genetic mapping information
Comments
Comments on Cytology

Left limit of break 1 from polytene analysis (FBrf0048677) Right limit of break 1 from polytene analysis (FBrf0080317) Left limit of break 2 from inclusion of egl (FBrf0083926)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
apt
(Takasu-Ishikawa et al., 2001, Gellon et al., 1997)
bw
(Dreesen et al., 1988)
Dcp-1
(Song et al., 1997)
egl
(Fitzpatrick et al., 1995)
Partially deleted / disrupted
Molecular Data
Completely deleted
AIMP3
(Marygold et al., 2007)
Partially deleted
Genes NOT Deleted / Disrupted
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (0)
    If no genes are listed here, it may be because the affected region is very large. The JBrowse insert above may show an error for the same reason, and other FlyBase tools such as CytoSearch may also fail for large regions. You can contact FlyBase for more help.
    In these cases, there will be no "Export to Hitlist" button to the left.
    Phenotypic Data
    In combination with other aberrations

    Lethal in combination with Df(2R)bw-W4, Df(2R)bw-W3a or Df(2R)bw-W3b.

    (Watanabe et al., 2009)

    No effect on In(1)wm4h position-effect variegation.

    (Wustmann et al., 1989)
    NOT in combination with other aberrations

    Homozygotes have electrophysiological defects, head defects and the ventral nerve cord fails to contract.

    (Takasu-Ishikawa et al., 2001)

    Heterozygotes with Byron exhibit about 2% eye pigmentation.

    (Henikoff et al., 1995)

    Heterozygosity for this deletion has no effect on the mutant ovarian phenotype of ovoD2.

    (Pauli et al., 1995)
    Stocks (2)
    Notes on Origin
    Discoverer

    Mohr, 28th Nov. 1931.

     
    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    The Df(2R)bw5 chromosome may act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{wvar}KR3-2", a stable "brown-red" variant of the P{3'WP-2,wvar}2Lt insertion), but the eye colour phenotype in the presence of Df(2R)bw5 overlaps the eye colour phenotype in a wild-type background so it cannot be unequivocally demonstrated that the deficiency chromosome uncovers a suppressor of telomeric silencing.

    (Mason et al., 2004)
    Synonyms and Secondary IDs (3)
    References (28)