FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
Allele: Dmel\Dcp-102132
Open Close
General Information
Symbol
Dmel\Dcp-102132
Species
D. melanogaster
Name
FlyBase ID
FBal0007995
Feature type
allele
Associated gene
Dmel\Dcp-1
Associated Insertion(s)
P{PZ}Dcp-102132
Carried in Construct
Also Known As
dcp-12132
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(McCall et al., 2003, Spradling et al., 1999, BDGP Project Members, 1994-1999)
Progenitor genotype
Associated Insertion(s)
P{PZ}Dcp-102132
Cytology
Description

Contains a 40bp partial P element insertion in the coding region of Dcp-1 and an in-frame stop codon within the 40bp insertion.

(Nandi et al., 2014)

P{PZ}Dcp-102132 disrupts both Dcp-1 and pita.

(McCall, 2004)

The P{PZ}Dcp-102132 insertion affects both Dcp-1 and pita, which have overlapping transcription units.

(Laundrie et al., 2003)

P{PZ} is inserted into the first exon of Dcp-1.

(Song et al., 1997)
Allele components
Component
Use(s)
Inserted element
P{PZ}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Dcp-102132 mutant fat bodies display robustly induced autophagy in fed larvae, higher than in wild-type. The level of autophagy is increased upon starvation.

      (Nandi et al., 2014)

      Mutant embryos show no abnormalities in the pattern of cell death.

      (Song et al., 1997)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer

      A. Spradling.

      Comments
      Comments

      Complements: chrwk06908. Complements: aptk15608. Complements: l(2)s4830s4830.

      (BDGP Project Members, 1994-1999)

      P{PZ}Dcp-102132 disrupts both Dcp-1 and pita. Several phenotypes that were originally attributed to loss of Dcp-1 in the P{PZ}Dcp-102132 line, including melanotic tumors, small imaginal discs, and dumpless egg chambers, have since been shown to be due to disruption of pita (see FBrf0167648).

      (McCall, 2004)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      11179
      (Moskalev, 2004)
      Dcp-102132
      PZ02132
      (McCall et al., 2003, Laundrie and McCall, 2002)
      dcp-12132
      (McCall and Steller, 1998, Song et al., 1997)
      l(2)02132
      (Song et al., 1997)
      Name Synonyms
      Secondary FlyBase IDs
        References (13)