FB2026_01 , released March 12, 2026
FB2026_01 , released March 12, 2026
CV Term Report
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General Information
Term programmed cell death ID (Ontology) GO:0012501 (Gene Ontology)
Definition A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
Comment
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  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      16
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 programmed cell death (all annotations which use CV term, excluding "NOT" statements)      16
     involved_in | programmed cell death      16
Spanning Tree (Parents/Children)
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  cellular process
   |__cell death
       |__programmed cell death  388 rec.
           |__apoptotic process 303 rec.
           |   |__anoikis(+)
           |   |__apoptotic mitochondrial changes(+) 12 rec.
           |   |__apoptotic process in bone marrow cell(+)
           |   |__apoptotic process in response to mitochondrial fragmentation
           |   |__apoptotic process involved in development(+) 25 rec.
           |   |__apoptotic signaling pathway(+) 58 rec.
           |   |__endothelial cell apoptotic process(+)
           |   |__epithelial cell apoptotic process(+)
           |   |__execution phase of apoptosis(+) 31 rec.
           |   |__fat cell apoptotic process(+)
           |   |__fibroblast apoptotic process(+)
           |   |__glial cell apoptotic process(+) 3 rec.
           |   |__hepatoblast apoptotic process
           |   |__inflammatory cell apoptotic process(+)
           |   |__leukocyte apoptotic process(+)
           |   |__melanocyte apoptotic process
           |   |__mesenchymal cell apoptotic process(+)
           |   |__muscle cell apoptotic process(+)
           |   |__myeloid cell apoptotic process(+)
           |   |__myofibroblast cell apoptotic process(+)
           |   |__neuron apoptotic process(+) 36 rec.
           |   |__regulation of apoptotic process(+) 219 rec.
           |   |__retinal cell apoptotic process(+) 2 rec.
           |__autolysis
           |__autophagic cell death 26 rec.
           |   |__regulation of autophagic cell death(+)
           |__cornification
           |   |__regulation of cornification(+)
           |__cuproptosis
           |__ferroptosis
           |   |__regulation of ferroptosis(+)
           |__granzyme-mediated programmed cell death signaling pathway
           |   |__granzyme-mediated apoptotic signaling pathway
           |__mitochondrial outer membrane permeabilization involved in programmed cell death 2 rec.
           |   |__positive regulation of mitochondrial membrane permeability involved in apoptotic process(+) 2 rec.
           |__programmed cell death in response to reactive oxygen species
           |   |__hydrogen peroxide-mediated programmed cell death(+)
           |   |__singlet oxygen-mediated programmed cell death
           |__programmed cell death in response to retinoic acid
           |__programmed cell death involved in cell development 80 rec.
           |   |__antipodal cell degeneration
           |   |__central B cell deletion(+)
           |   |__ectopic germ cell programmed cell death 12 rec.
           |   |__larval midgut cell programmed cell death 25 rec.
           |   |__nurse cell apoptotic process(+) 18 rec.
           |   |__retinal cell programmed cell death(+) 28 rec.
           |   |__synergid death
           |__programmed necrotic cell death 5 rec.
           |   |__necroptotic process(+)
           |   |__programmed necrotic cell death in response to starvation
           |   |__regulation of mitochondrial membrane permeability involved in programmed necrotic cell death 1 rec.
           |   |__regulation of programmed necrotic cell death(+) 3 rec.
           |__pyroptotic cell death
           |   |__cytotoxic T cell pyroptotic cell death
           |__regulation of programmed cell death 260 rec.
           |   |__negative regulation of programmed cell death(+) 139 rec.
           |   |__positive regulation of programmed cell death(+) 92 rec.
           |   |__regulation of apoptotic process(+) 219 rec.
           |   |__regulation of autophagic cell death(+)
           |   |__regulation of cornification(+)
           |   |__regulation of ferroptosis(+)
           |   |__regulation of hydrogen peroxide-mediated programmed cell death(+)
           |   |__regulation of plant-type hypersensitive response(+)
           |   |__regulation of programmed necrotic cell death(+) 3 rec.
           |   |__regulation of retinal cell programmed cell death(+) 14 rec.
           |__symbiont-induced defense-related programmed cell death
               |__plant-type hypersensitive response(+)
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Synonyms
  • "caspase-independent apoptosis" RELATED
    "caspase-independent cell death" NARROW
    "non-apoptotic programmed cell death" NARROW
    "nonapoptotic programmed cell death" NARROW
    "PCD" RELATED
    "RCD" RELATED
    "regulated cell death" BROAD
Secondary IDs
hide External Crossreferences & Linkouts
Reactome:R-HSA-5357801 "Programmed Cell Death"
Wikipedia:Programmed_cell_death