FB2022_03, released June 9, 2022

Aberration: Dmel\Df(2L)A178

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General Information
Symbol
Df(2L)A178
Species
D. melanogaster
Name
Deficiency (2L) Aaron
FlyBase ID
FBab0001397
Feature type
chromosomal_deletion
Computed Breakpoints include

35B2;35B3

Features within 35B2--35B3
Sequence coordinates
2L:14,497,086..14,499,160 [+] (Df(2L)A178:bk1)
(Chia et al., 1985)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
Mutagen
X ray
(McNabb et al., 1996, Fossett et al., 1994)
Class of aberration (relative to wild type)
chromosomal_deletion
(FlyBase, 2007)
Class of aberration (relative to progenitor)
chromosomal_deletion
(McNabb et al., 1996, Roote et al., 1996, Gubb et al., 1990, Gubb et al., 1986, Chia et al., 1985, Gubb et al., 1985, Ashburner et al., 1983, Ashburner et al., 1982)
Breakpoints

35B2;35B3

(Gubb et al., 1985, Ashburner et al., 1983, Ashburner et al., 1982)

[];[]

(Roote et al., 1996, Gubb et al., 1990, Chia et al., 1985)

35B1-35B2;35B1-35B2

(McNabb et al., 1996, Gubb et al., 1986)
Causes alleles
nocA178
(Cheah et al., 1994)
Carries alleles
Transposon Insertions
Formalized genetic data

bk1 hits noc << Adh << bk2 << mol

Genetic mapping information
Comments

Lesion within noc.

(Cheah et al., 1994)
Comments on Cytology

Cytologically invisible deletion.

(Roote et al., 1996, Gubb et al., 1990, Chia et al., 1985)

Cytologically complex.

(Ashburner et al., 1982)

Left limit of break 1 from polytene analysis (FBrf0038047) Right limit of break 1 from inclusion of Adh (FBrf0038047) Limits of break 2 from polytene analysis (FBrf0038047)

Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Genes NOT Deleted / Disrupted
Complementation Data
 
Ance
(Fossett et al., 1994, Ashburner et al., 1982)
Ankrd49
(Ashburner et al., 1982)
Arpc1
(Ashburner et al., 1982)
b
(Ashburner et al., 1982)
Ca-α1D
(Fossett et al., 1994)
CIAPIN1
(Ashburner et al., 1982, Ashburner et al., 1982)
ck
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Cul3
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
CycE
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
DCTN5-p25
(Ashburner et al., 1982)
elA
(Davis et al., 1997, Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
elB
(Davis et al., 1997, Roote et al., 1996, Fossett et al., 1994)
esg
(Fossett et al., 1994)
kuz
(Fossett et al., 1994)
l(2)34Db
(Fossett et al., 1994, Ashburner et al., 1982)
l(2)34Fc
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
l(2)34Fd
(Roote et al., 1996, Ashburner et al., 1982)
l(2)35De
(Fossett et al., 1994)
lace
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
mol
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
mRpL4
(Fossett et al., 1994)
ms(2)34Fe
(Roote et al., 1996)
NimA
(Ashburner et al., 1982)
NimC3
(Fossett et al., 1994, Ashburner et al., 1982)
Pburs
(Davis et al., 1997, Roote et al., 1996, Ashburner et al., 1982, Ashburner et al., 1982)
Pgant35A
(Roote et al., 1996, Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
PolD3
(Ashburner et al., 1982, Ashburner et al., 1982)
PolG1
(Ashburner et al., 1982)
PolG2
(Ashburner et al., 1982)
Polr2C
(Fossett et al., 1994, Ashburner et al., 1982)
rk
(Fossett et al., 1994, Ashburner et al., 1982)
Rnmt
(Ashburner et al., 1982)
sna
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Sos
(Ashburner et al., 1982)
stc
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Su(H)
(Ashburner et al., 1982)
TfIIS
(Fossett et al., 1994)
THG
(Ashburner et al., 1982)
Uxt
(Fossett et al., 1994)
wb
(Fossett et al., 1994, Ashburner et al., 1982)
wek
(Fossett et al., 1994)
wor
(Fossett et al., 1994, Ashburner et al., 1982, Ashburner et al., 1982)
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location
    Phenotypic Data
    In combination with other aberrations

    Weakly suppresses the zeste phenotype in a z1 w11E4; Tp(1;2)TE35B homologue.

    (Gubb et al., 1990)
    NOT in combination with other aberrations

    Chromosome acts as a weak trans-suppressor of a physical interaction between tandemly duplicated copies of w+, an interaction that is required for the suppression of genes by z1.

    (Gubb et al., 1990)

    Semilethal with noc. Males and females homozygous viable and fertile with strong noc and osp phenotypes

    Stocks (2)
    Notes on Origin
    Discoverer

    Aaron.

     

    selected as ADH null on 1-penten-3-ol. Induced with, but genetically separable from T(2;3)CA3.

    Balancer / Genotype Variants of the Aberration
     
    Separable Components
     
    Other Comments
     

    Reported to delete Adhr in error; see FBrf0141768 for correction.

    (Roote et al., 1996)

    nLA178 chromosome carries an independent translocation, T(2;3)CA3, that can be removed by exchange.

    (Ashburner et al., 1982)
    Synonyms and Secondary IDs (4)
    Reported As
    Symbol Synonym
    A178
    (Fossett et al., 1994)
    Df(2L)A178
    Df(2L)A178178
    Name Synonyms
    Deficiency (2L) Aaron
    Secondary FlyBase IDs
      References (17)